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Dr Edward Parkin

Senior Lecturer in Biomedicine

  1. Chapter
  2. Published

    Alpha-Secretase and Alzheimer's disease

    Parkin, E., 2008, Recent advances in the biology of secretases, key proteases in Alzheimer's disease. Araki, W. (ed.). Research Signpost, p. 183-211 29 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  3. Published

    The role of proteolysis in Alzheimer's disease.

    Hooper, N. M., Trew, A. J., Parkin, E. T. & Turner, A. J., 2000, Cellular peptidases in immune functions and diseases. Langner, J. & Ansorge, S. (eds.). Plenum, p. 379-390 12 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  4. Published

    Distribution of presenilins and amyloid precursor protein in detergent-insoluble membrane domains.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 1999, Alzheimer's disease : methods and protocols. Walker, J. M. (ed.). Humana Press, p. 345-360 16 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  5. Published

    Distribution of presenilins and amyloid precursor protein in detergent-insoluble membrane microdomains

    Parkin, E., Turner, A. & Hooper, N., 1999, Alzheimer's disease: methods and protocols. Hooper, N. M. (ed.). Humana Press, p. 345-360 16 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  6. Published

    Glycosylation and glycosylphosphatidylinositol membrane anchors

    Turner, A., Parkin, E. & Hooper, N., 1996, Regulatory protein modification: techniques and protocols. Hemmings, H. C. (ed.). Humana Press, Vol. 30. p. 395-427 33 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  7. Other
  8. Published

    The Alzheimer's amyloid precursor protein a-secretase and the angiotensin converting enzyme secretase exhibit closely related enzyme activities.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 2000.

    Research output: Contribution to conference - Without ISBN/ISSN Other

  9. Journal article
  10. E-pub ahead of print

    Protective effect of PDE4B subtype-specific inhibition in an App knock-in mouse model for Alzheimer's disease

    Armstrong, P., Güngör, H., Anongjanya, P., Tweedy, C., Parkin, E., Johnston, J., Carr, I. M., Dawson, N. & Clapcote, S. J., 23/03/2024, (E-pub ahead of print) In: Neuropsychopharmacology.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    BACE1 Overexpression Reduces SH-SY5Y Cell Viability Through a Mechanism Distinct from Amyloid-β Peptide Accumulation: Beta Prime-Mediated Competitive Depletion of sAβPPα

    Owens, L., Bracewell, J., Benedetto, A., Dawson, N., Gaffney, C. & Parkin, E., 5/04/2022, In: Journal of Alzheimer's Disease. 86, 3, p. 1201-1220 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    The Amyloid Precursor Protein Plays Differential Roles in the UVA Resistance and Proliferation of Human Retinal Pigment Epithelial Cells

    Sultan, F. & Parkin, E., 30/03/2022, In: Protein and Peptide Letters. 29, 4, p. 313-327 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    The orphan drug dichloroacetate reduces amyloid beta-peptide production whilst promoting non-amyloidogenic proteolysis of the amyloid precursor protein

    Parkin, E. T., Hammond, J. E., Owens, L. & Hodges, M. D., 13/01/2022, In: PLoS ONE. 17, 1, 21 p., e0255715.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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