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Research

Dr Edward Parkin

Senior Lecturer in Biomedicine

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  1. 2005
  2. Published

    Tumor Necrosis Factor- Convertase (ADAM17) Mediates Regulated Ectodomain Shedding of the Severe-acute Respiratory Syndrome-Coronavirus (SARS-CoV) Receptor, Angiotensin-converting Enzyme-2 (ACE2).

    Lambert, D. W., Yarski, M., Warner, F. J., Thornhill, P., Parkin, E. T., Smith, A. I., Hooper, N. M. & Turner, A. J., 26/08/2005, In: Journal of Biological Chemistry. 280, 34, p. 30113-30119 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Herpes simplex virus interferes with amyloid precursor protein processing.

    Shipley, S. J., Parkin, E. T., Itzhaki, R. F. & Dobson, C. B., 18/08/2005, In: BMC Microbiology. 5, p. 48

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. 2004
  5. Published

    The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein.

    Allinson, T. M. J., Parkin, E. T., Condon, T. P., Schwager, S. L. U., Sturrock, E. D., Turner, A. J. & Hooper, N. M., 06/2004, In: European Journal of Biochemistry. 271, 12, p. 2539-2547 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Dual Mechanisms for Shedding of the Cellular Prion Protein.

    Parkin, E. T., Watt, N. T., Turner, A. J. & Hooper, N. M., 19/03/2004, In: Journal of Biological Chemistry. 279, 12, p. 11170-11178 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Secretase-mediated cell surface shedding of the angiotensin-converting enzyme.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 2004, In: Protein and Peptide Letters. 11, p. 423-432 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. 2003
  9. Published

    ADAMs family members as amyloid precursor protein -secretases.

    Allinson, T. M. J., Parkin, E. T., Turner, A. J. & Hooper, N. M., 1/11/2003, In: Journal of Neuroscience Research. 74, 3, p. 342-352 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    The ectodomain shedding of angiotensin-converting enzyme is independent of its localisation in lipid rafts.

    Parkin, E. T., Tan, F., Skidgel, R. A., Turner, A. J. & Hooper, N. M., 1/08/2003, In: Journal of Cell Science. 116, 15, p. 3079-3087 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. 2002
  12. Published

    Structure-Activity Relationship of Hydroxamate-Based Inhibitors on the Secretases that Cleave the Amyloid Precursor Protein, Angiotensin Converting Enzyme, CD23, and Pro-Tumor Necrosis Factor.

    Parkin, E. T., Trew, A., Christie, G., Faller, A., Mayer, R., Turner, A. J. & Hooper, N. M., 16/04/2002, In: Biochemistry. 41, 15, p. 4972-4981 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    Inactivation of a tachykinin-related peptide: identification of four neuropeptide-degrading enzymes in neuronal membranes of insects from four different orders.

    Isaac, R. E., Parkin, E. T., Keen, J. N., Nässel, D. R., Siviter, R. J. & Shirras, A. D., 04/2002, In: Peptides. 23, 4, p. 725-733 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. 2001
  15. Published

    Differential effects of glycosphingolipids on the detergent-insolubility of the glycosylphosphatidylinositol-anchored membrane dipeptidase.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 15/08/2001, In: Biochemical Journal. 358, 1, p. 209-216 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    A Point Mutation in the Juxtamembrane Stalk of Human Angiotensin I-converting Enzyme Invokes the Action of a Distinct Secretase.

    Alfalah, M., Parkin, E. T., Jacob, R., Sturrock, E. D., Mentele, R., Turner, A. J., Hooper, N. M. & Naim, H. Y., 15/06/2001, In: Journal of Biological Chemistry. 276, 24, p. 21105-21109 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. 2000
  18. Published

    The Alzheimer's amyloid precursor protein a-secretase and the angiotensin converting enzyme secretase exhibit closely related enzyme activities.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 2000.

    Research output: Contribution to conference - Without ISBN/ISSN › Other

  19. Published

    The role of proteolysis in Alzheimer's disease.

    Hooper, N. M., Trew, A. J., Parkin, E. T. & Turner, A. J., 2000, Cellular peptidases in immune functions and diseases. Langner, J. & Ansorge, S. (eds.). Plenum, p. 379-390 12 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  20. 1999
  21. Published

    Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 15/11/1999, In: Biochemical Journal. 344, 1, p. 23-30 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. Published

    Caveolae-like membranes and the amyloid precursor protein : a critical reassessment.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 06/1999, In: Journal of Neurochemistry. 72, Supple, p. S71

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    Characterization of Detergent-Insoluble Complexes Containing the Familial Alzheimer's Disease-Associated Presenilins.

    Parkin, E. T., Hussain, I., Karran, E. H., Turner, A. J. & Hooper, N. M., 04/1999, In: Journal of Neurochemistry. 72, 4, p. 1534-1543 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    Modulation of phosphatidylcholine biosynthesis in celery by exogenous fatty acids.

    Parkin, E. T. & Rolphe, C. E., 15/01/1999, In: Phytochemistry. 50, 1, p. 47-51 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    Caveolae-like membranes and the amyloid precursor protein : a critical reassessment.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 1999, In: British Neuroscience Association Abstracts. 15, p. 59

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  26. Published

    Distribution of presenilins and amyloid precursor protein in detergent-insoluble membrane domains.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 1999, Alzheimer's disease : methods and protocols. Walker, J. M. (ed.). Humana Press, p. 345-360 16 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  27. Published

    Distribution of presenilins and amyloid precursor protein in detergent-insoluble membrane microdomains

    Parkin, E., Turner, A. & Hooper, N., 1999, Alzheimer's disease: methods and protocols. Hooper, N. M. (ed.). Humana Press, p. 345-360 16 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  28. 1998
  29. Published

    Cell proliferation and CTP: cholinephosphate cytidyhltraitsferase activity in higher plahts

    Parkin, E. T. & Rolph, C. E., 1/08/1998, In: Biochemical Society Transactions. 26, 3, p. S219

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  30. Published

    Detergent solubility and processing of the familial Alzheimer's disease-related presenilin proteins

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 1/08/1998, In: Biochemical Society Transactions. 26, 3, p. S241

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  31. 1997
  32. Published

    The amyloid precursor protein is not enriched in caveolae-like, detergent-insoluble membrane microdomains

    Parkin, E., Hussain, I., Turner, A. J. & Hooper, N. M., 11/1997, In: Journal of Neurochemistry. 69, 5, p. 2179-2188 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  33. 1996
  34. Published

    A role for calcium and annexins in the formation of caveolae

    Parkin, E., Turner, A. J. & Hooper, N. M., 08/1996, In: Biochemical Society Transactions. 24, 3, p. 444S 1 p.

    Research output: Contribution to Journal/Magazine › Journal article

  35. Published

    Glycosylation and glycosylphosphatidylinositol membrane anchors

    Turner, A., Parkin, E. & Hooper, N., 1996, Regulatory protein modification: techniques and protocols. Hemmings, H. C. (ed.). Humana Press, Vol. 30. p. 395-427 33 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

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