Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage.

Andrews, E., Palecek, J., Sergeant, J., Taylor, E., Lehmann, A. & Watts, F., 01/2005, In: Molecular and Cellular Biology. 25, 1, p. 185-196 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The cancer-free phenotype in trichothiodystrophy is unrelated to its repair defect

Berneburg, M., Clingen, P. H., Harcourt, S. A., Lowe, J. E., Taylor, E. M., Green, M. H., Krutmann, J., Arlett, C. F. & Lehmann, A. R., 15/01/2000, In: Cancer Research. 60, 2, p. 431-438 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

PrimPol bypasses UV photoproducts during chromosomal DNA replication

Bianchi, J., Rudd, S. G., Jozwiakowski, S. K., Bailey, L. J., Soura, V., Taylor, E., Stevanovic, I., Green, A. J., Stracker, T. H., Lindsay, H. & Doherty, A. J., 21/11/2013, In: Molecular Cell. 52, 4, p. 566-573 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Two individuals with features of both xeroderma pigmentosum and trichothiodystrophy highlight the complexity of the clinical outcomes of mutations in the XPD gene.

Broughton, B. C., Berneburg, M., Fawcett, H., Taylor, E. M., Arlett, C. F., Nardo, T., Stefanini, M., Menefee, E., Price, V. H., Queille, S., Sarasin, A., Bohnert, E., Krutmann, J., Davidson, R., Kraemer, K. H. & Lehmann, A. R., 10/2001, In: Human Molecular Genetics. 10, 22, p. 2539-2547 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

1st MRC Human Genetics Symposium: maintenance of genomic stability

Carr, A. M. & Taylor, E. M., 26/11/1998, In: BBA - Reviews on Cancer. 1378, 3, p. R55-R58 4 p.

Research output: Contribution to Journal/Magazine › Journal article

Atm-dependent interactions of a mammalian chk1 homolog with meiotic chromosomes.

Flaggs, G., Plug, A. W., Dunks, K. M., Mundt, K. E., Ford, J. C., Quiggle, M. R., Taylor, E. M., Westphal, C. H., Ashley, T., Hoekstra, M. F. & Carr, A. M., 1/12/1997, In: Current Biology. 7, 12, p. 977-986 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Molecular basis for PrimPol recruitment to replication forks by RPA

Guilliam, T. A., Brissett, N. C., Ehlinger, A., Keen, B. A., Kolesar, P., Taylor, E. M., Bailey, L., Lindsay, H. D., Chazin, W. J. & Doherty, A. J., 23/05/2017, In: Nature Communications. 8, 14 p., 15222.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The genetics of the repair of 5-azacytidine-mediated DNA damage in the fission yeast Schizosaccharomyces pombe.

Hegde, V., McFarlane, R. J., Taylor, E. M. & Price, C., 06/1996, In: Molecular and General Genetics. 251, 4, p. 483-492 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Cip29 is phosphorylated following activation of the DNA damage response in Xenopus egg extracts

Holden, J., Taylor, E. M. & Lindsay, H. D., 17/07/2017, In: PLoS ONE. 12, 7, 20 p., e0181131.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities

Ju, L., Wing, J., Taylor, E., Brandt, R., Slijepcevic, P., Horsch, M., Rathkolb, B., Racz, I., Becker, L., Hans, W., Adler, T., Beckers, J., Rozman, J., Klingenspor, M., Wolf, E., Zimmer, A., Klopstock, T., Busch, D., Gailus-Durner, V. & Fuchs, H. & 3 others, Hrabe de Angelis, M., van der Horst, G. & Lehmann, A., 1/05/2013, In: DNA Repair. 12, 5, p. 356-366 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes.

Keegan, K. S., Holtzman, D. A., Plug, A. W., Christenson, E. R., Brainerd, E. E., Flaggs, G., Bentley, N. J., Taylor, E. M., Meyn, M. S., Moss, S. B., Carr, A. M., Ashley, T. & Hoekstra, M. F., 1/10/1996, In: Genes and Development. 10, 19, p. 2423-2437 15 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Crucial role of the NSE1 RING domain in Smc5/6 stability and FANCM-independent fork progression

Lorite, N. P., Apostolova, S., Guasch-Vallés, M., Pryer, A., Unzueta, F., Freire, R., Solé-Soler, R., Pedraza, N., Dolcet, X., Garí, E., Agell, N., Taylor, E. M., Colomina, N. & Torres-Rosell, J., 31/12/2024, In: Cellular and Molecular Life Sciences : CMLS. 81, 1, 251.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Composition and architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) complex.

Sergeant, J., Taylor, E., Palecek, J., Fousteri, M., Andrews, E., Sweeney, S., Shinagawa, H. & Watts, F., 01/2005, In: Molecular and Cellular Biology. 25, 1, p. 172-184 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis.

Taylor, E. M., Cecillon, S. M., Bonis, A., Chapman, J. R., Povirk, L. F. & Lindsay, H. D., 01/2010, In: Nucleic Acids Research. 38, 2, p. 441-454 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Identification of the proteins, including MAGE-G1, that make up the human SMC5-6 protein complex.

Taylor, E. M., Copsey, A., Hudson, J., Vidot, S. & Lehmann, A., 15/02/2008, In: Molecular and Cellular Biology. 28, 4, p. 1197-1206 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex

Taylor, E. M., Moghraby, J. S., Lees, J. H., Smit, B., Moens, P. B. & Lehmann, A. R., 06/2001, In: Molecular Biology of the Cell. 12, 6, p. 1583-1594 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Xeroderma pigmentosum and trichothiodystrophy are associated with different mutations in the XPD (ERCC2) repair/transcription gene.

Taylor, E. M., Broughton, B. C., Botta, E., Stefanini, M., Sarasin, A., Jaspers, N. G., Fawcett, H., Harcourt, S. A., Arlett, C. F. & Lehmann, A. R., 6/08/1997, In: Proceedings of the National Academy of Sciences of the United States of America. 94, 16, p. 8658-8663 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

5-Azacytidine treatment of the fission yeast leads to cytotoxicity and cell cycle arrest.

Taylor, E. M., McFarlane, R. J. & Price, C., 11/1996, In: Molecular and General Genetics. 253, 1-2, p. 128-137 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Conservation of eukaryotic DNA repair mechanisms.

Taylor, E. M. & Lehmann, A. R., 1998, In: International Journal of Radiation Biology. 74, 3, p. 277-286 10 p.

Research output: Contribution to Journal/Magazine › Literature review

Depletion of Uhrf1 inhibits chromosomal DNA replication in Xenopus egg extracts

Taylor, E., Bonsu-Dartnall, N., Price, J. & Lindsay, H., 2013, In: Nucleic Acids Research. 41, 16, p. 7725-7737 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

DNA replication stress and cancer: cause or cure?

Taylor, E. M. & Lindsay, H. D., 01/2016, In: Future Oncology. 12, 2, p. 221-237 17 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review