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Research

Dr Federico Rojas Martinez

Lecturer in Infection Biology

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  1. 2022
  2. Published

    Extracellular release of two peptidases dominates generation of the trypanosome quorum-sensing signal

    Tettey, M. D., Rojas, F. & Matthews, K. R., 9/06/2022, In: Nature Communications. 13, 1, 14 p., 3322.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. 2021
  4. Published

    Single-cell transcriptomic analysis of bloodstream Trypanosoma brucei reconstructs cell cycle progression and developmental quorum sensing.

    Briggs, EM., Rojas, F., McCulloch, R., Matthews, KR. & Otto, TD., 6/09/2021, In: Nature Communications. 12, 15 p., 5268.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    Basement membrane proteins as a substrate for efficient Trypanosoma brucei differentiation in vitro

    Rojas, F., Cayla, M. & Matthews, KR., 28/04/2021, In: PLoS Neglected Tropical Diseases. 15, 4, 11 p., e0009284.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. 2019
  7. Published

    Quorum sensing in African trypanosomes.

    Rojas Martinez, F. & Matthews, K. R., 31/12/2019, In: Current Opinion in Microbiology. 52, p. 124-129 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Positional dynamics and glycosomal recruitment of developmental regulators during trypanosome differentiation

    Szö Ő Rbalazs, B., Simon, D. V., Rojas, F., Young, J., Robinson, D. R., Krüger, T., Engstler, M. & Matthews, K. R., 1/07/2019, In: MBio. 10, 4, e00875-19.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    African trypanosomes.

    Cayla, M., Rojas Martinez, F., Silvester, E., Venter, F. & Matthews, K. R., 29/04/2019, In: Parasites & vectors. 12, 1, 8 p., 190.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Positional dynamics and glycosomal recruitment of developmental regulators during trypanosome differentiation

    Rojas Martinez, F., 10/04/2019

    Research output: Other contribution

  11. Published

    Oligopeptide Signaling through TbGPR89 Drives Trypanosome Quorum Sensing.

    Rojas Martinez, F., Silvester, E., Young, J., Milne, R., Tettey, M. D., Houston, D. R., Walkinshaw, M. D., Perez-Pi, I., Auer, M., Denton, H., Smith, T. K., Thompson, J. & Matthews, K. R., 10/01/2019, In: Cell. 176, 1-2, p. 306-317.e16 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. 2017
  13. Published

    Stress-Induced Protein S-Glutathionylation and S-Trypanothionylation in African Trypanosomes - A Quantitative Redox Proteome and Thiol Analysis

    Ulrich, K., Finkenzeller, C., Merker, S., Rojas, F., Matthews, K., Ruppert, T. & Krauth-Siegel, R. L., 20/09/2017, In: Antioxidants and Redox Signaling. 27, 9, p. 517-533 17 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    The ubiquitin-conjugating enzyme CDC34 is essential for cytokinesis in contrast to putative subunits of a SCF complex in Trypanosoma brucei.

    Rojas, F., Koszela, J., Búa, J., Llorente, B., Burchmore, R., Auer, M., Mottram, JC. & Téllez-Iñón, MT., 13/06/2017, In: PLoS Neglected Tropical Diseases. 11, 6, 22 p., e0005626.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. 2016
  16. Published

    Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal protein expression.

    Antwi, EB., Haanstra, JR., Ramasamy, G., Jensen, B., Droll, D., Rojas, F., Minia, I., Terrao, M., Mercé, C., Matthews, K., Myler, PJ., Parsons, M. & Clayton, C., 26/04/2016, In: BMC Genomics. 17, 16 p., 306.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. 2014
  18. Published

    Transcriptome-wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co-transcriptional degradation in determining mRNA levels.

    Fadda, A., Ryten, M., Droll, D., Rojas, F., Färber, V., Haanstra, JR., Merce, C., Bakker, BM., Matthews, K. & Clayton, C., 9/10/2014, In: Molecular Microbiology. 94, 2, p. 307-326 20 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    The silicon trypanosome: a test case of iterative model extension in systems biology.

    Achcar, F., Fadda, A., Haanstra, JR., Kerkhoven, EJ., Kim, DH., Leroux, AE., Papamarkou, T., Rojas, F., Bakker, BM., Barrett, MP., Clayton, C., Girolami, M., Krauth-Siegel, R. L., Matthews, K. R. & Breitling, R., 31/05/2014, In: Advances in Microbial Physiology. 64, p. 115-143 29 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. Published

    Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei.

    Mony, BM., MacGregor, P., Ivens, A., Rojas, F., Cowton, A., Young, J., Horn, D. & Matthews, K., 30/01/2014, In: Nature. 505, p. 681–685 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. 2013
  22. Published

    Bloodstream form pre-adaptation to the tsetse fly in Trypanosoma brucei.

    Rico, E., Rojas, F., Mony, BM., Szoor, B., Macgregor, P. & Matthews, KR., 30/11/2013, In: Frontiers in cellular and infection microbiology. 3, 15 p., 78.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    Identification of a Wee1-like kinase gene essential for procyclic Trypanosoma brucei survival.

    Boynak, NY., Rojas, F., D'Alessio, C., Vilchez, L. SC., Rodriguez, V., Ghiringhelli, PD. & Téllez-Iñón, MT., 5/11/2013, In: PLoS ONE. 8, 11, 14 p., e79364.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    Stable transformation of pleomorphic bloodstream form Trypanosoma brucei.

    MacGregor, P., Rojas, F., Dean, S. & Matthews, KR., 31/08/2013, In: Molecular and Biochemical Parasitology. 190, 2, p. 60-62 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    Metabolomics guides rational development of a simplified cell culture medium for drug screening against Trypanosoma brucei.

    Creek, DJ., Nijagal, B., Kim, DH., Rojas, F., Matthews, KR. & Barrett, MP., 14/05/2013, In: Antimicrobial Agents and Chemotherapy. 57, 6, p. 2768-2779 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  26. 2006
  27. Published

    Trypanosoma cruzi Tcp12CKS1 interacts with parasite CRKs and rescues the p13SUC1 fission yeast mutant.

    Muñoz, MJ., Santori, MI., Rojas, F., Gómez, EB. & Téllez-Iñón, MT., 30/06/2006, In: Molecular and Biochemical Parasitology. 147, 2, p. 154-162 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  28. 2005
  29. Published

    Trypanosoma cruzi histone H1 is phosphorylated in a typical cyclin dependent kinase site accordingly to the cell cycle.

    da, C. JP., Nakayasu, ES., Elias, MC., Pimenta, DC., Téllez-Iñón, MT., Rojas, F., Muñoz, MJ., Almeida, IC. & Schenkman, S., 31/03/2005, In: Molecular and Biochemical Parasitology. 140, 1, p. 75-86 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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