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Dr Jonathan Higham

Senior Research Associate

  1. 2024
  2. Published

    Evergene: an interactive webtool for large-scale gene-centric analysis of primary tumours

    Kennedy, A., Richardson, E., Higham, J., Kotsantis, P., Mort, R. & Shih, B. B.-J., 28/06/2024, In: Bioinformatics advances. 4, 1, vbae092.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. 2022
  4. Published

    Local CpG density affects the trajectory and variance of age-associated DNA methylation changes

    Higham, J., Kerr, L., Zhang, Q., Walker, R. M., Harris, S. E., Howard, D. M., Hawkins, E. L., Sandu, A.-L., Steele, J. D., Waiter, G. D., Murray, A. D., Evans, K. L., McIntosh, A. M., Visscher, P. M., Deary, I. J., Cox, S. R. & Sproul, D., 17/10/2022, In: Genome Biology. 23, 216.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. 2021
  6. Published

    An epigenetic predictor of death captures multi-modal measures of brain health

    Hillary, R. F., Stevenson, A. J., Cox, S. R., McCartney, D. L., Harris, S. E., Seeboth, A., Higham, J., Sproul, D., Taylor, A. M., Redmond, P., Corley, J., Pattie, A., Hernández, M. C. V., Muñoz-Maniega, S., Bastin, M. E., Wardlaw, J. M., Horvath, S., Ritchie, C. W., Spires-Jones, T. L. & McIntosh, A. M. & 3 others, Evans, K. L., Deary, I. J. & Marioni, R. E., 31/08/2021, In: Molecular Psychiatry. 2, p. 3806-3816 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG islands

    Masalmeh, R. H. A., Taglini, F., Rubio-Ramon, C., Musialik, K. I., Higham, J., Davidson-Smith, H., Kafetzopoulos, I., Pawlicka, K. P., Finan, H. M., Clark, R., Wills, J., Finch, A. J., Murphy, L. & Sproul, D., 29/01/2021, In: Nature Communications. 12, 1, 694.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. 2020
  9. Published

    Entropy of proteins using multiscale cell correlation

    Chakravorty, A., Higham, J. & Henchman, R. H., 23/11/2020, In: Journal of Chemical Information and Modeling. 60, 11, p. 5540-5551 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    Comparison of Free-Energy Methods to Calculate the Barriers for the Nucleophilic Substitution of Alkyl Halides by Hydroxide

    Ali, H. S., Higham, J., De Visser, S. P. & Henchman, R. H., 6/08/2020, In: Journal of Physical Chemistry B. 124, 31, p. 6835-6842 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation

    Patani, H., Rushton, M. D., Higham, J., Teijeiro, S. A., Oxley, D., Cutillas, P., Sproul, D. & Ficz, G., 22/07/2020, In: Nature Communications. 11, 3671.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. 2019
  13. Published

    Age-related clonal haemopoiesis is associated with increased epigenetic age

    Robertson, N. A., Hillary, R. F., McCartney, D. L., Terradas-Terradas, M., Higham, J., Sproul, D., Deary, I. J., Kirschner, K., Marioni, R. E. & Chandra, T., 19/08/2019, In: Current Biology. 29, 16, p. R786-R787 2 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Entropy of Simulated Liquids Using Multiscale Cell Correlation

    Ali, H. S., Higham, J. & Henchman, R. H., 31/07/2019, In: Entropy. 21, 8, 750.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG islands

    Ali Masalmeh, R. H., Rubio-Ramon, C., Taglini, F., Higham, J., Davidson-Smith, H., Clark, R., Wills, J., Finch, A. J., Murphy, L. & Sproul, D., 21/06/2019, bioRxiv.

    Research output: Working paperPreprint

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