Costs and staffing resource requirements for adaptive clinical trials: quantitative and qualitative results from the Costing Adaptive Trials project

Wilson, N., Biggs, K., Bowden, S., Brown, J., Dimairo, M., Flight, L., Hall, J., Hockaday, A., Jaki, T., Lowe, R., Murphy, C., Pallmann, P., Pilling, M. A., Snowdon, C., Sydes, M. R., Villar, S. S., Weir, C. J., Welburn, J., Yap, C., Maier, R., & 2 othersHancock, H. & Wason, J. M. S., 26/10/2021, In: BMC Medicine. 19, 1, 17 p., 251.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A permutation test for assessing the presence of individual differences in treatment effects

Chang, C., Jaki, T., Sadiq, M. S., Kuhlemeier, A., Feaster, D., Cole, N., Lamont, A., Oberski, D., Desai, Y. & Lee Van Horn, M., 1/11/2021, In: Statistical Methods in Medical Research. 30, 11, p. 2369-2381 13 p.

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Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study

Khoo, S. H., Fitzgerald, R., Fletcher, T., Ewings, S., Jaki, T., Lyon, R., Downs, N., Walker, L., Tansley-Hancock, O., Greenhalf, W., Woods, C., Reynolds, H., Marwood, E., Mozgunov, P., Adams, E., Bullock, K., Holman, W., Bula, M. D., Gibney, J. L., Saunders, G., & 18 othersCorkhill, A., Hale, C., Thorne, K., Chiong, J., Condie, S., Pertinez, H., Painter, W., Wrixon, E., Johnson, L., Yeats, S., Mallard, K., Radford, M., Fines, K., Shaw, V., Owen, A., Lalloo, D. G., Jacobs, M. & Griffiths, G., 12/11/2021, In: Journal of Antimicrobial Chemotherapy. 76, 12, p. 3286-3295 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Practical recommendations for implementing a Bayesian adaptive phase I design during a pandemic

Ewings, S., Saunders, G., Jaki, T. & Mozgunov, P., 20/01/2022, In: BMC Medical Research Methodology. 22, 1, 15 p., 25.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The need for reporting guidelines for early phase dose-finding trials: Dose-Finding CONSORT Extension

Yap, C., Bedding, A., de Bono, J., Dimairo, M., Espinasse, A., Evans, J., Hopewell, S., Jaki, T., Kightley, A., Lee, S., Liu, R., Mander, A., Solovyeva, O. & Weir, C. J., 31/01/2022, In: Nature Medicine. 28, 1, p. 6-7 2 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A dose-finding design for dual-agent trials with patient-specific doses for one agent with application to an opiate detoxification trial

Mozgunov, P., Cro, S., Lingford-Hughes, A., Paterson, L. M. & Jaki, T., 31/03/2022, In: Pharmaceutical Statistics. 21, 2, p. 476-495 20 p.

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An order restricted multi-arm multi-stage clinical trial design

Serra, A., Mozgunov, P. & Jaki, T., 30/04/2022, In: Statistics in Medicine. 41, 9, p. 1613-1626 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Individual differences in the effects of the ACTION-PAC intervention: an application of personalized medicine in the prevention and treatment of obesity

Kuhlemeier, A., Jaki, T., Jimenez, E. Y., Kong, A. S., Gill, H., Chang, C., Resnicow, K., Wilson, D. K. & Van Horn, M. L., 30/04/2022, In: Journal of Behavioral Medicine. 45, 2, p. 211-226 16 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A Benchmark for Dose Finding Studies with Unknown Ordering

Mozgunov, P., Paoletti, X. & Jaki, T., 31/07/2022, In: Biostatistics. 23, 3, p. 721-737 17 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

What is the expected benefit of patient-centric clinical development in oncology?

Serra, A., Mozgunov, P., Jaki, T. & Rigat, F., 31/07/2022, In: Journal of Biopharmaceutical Statistics. 32, 3, p. 414-426 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review