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Research

Professor Thomas Jaki

Formerly at Lancaster University

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  1. 2016
  2. Published

    A false sense of security? can tiered approach be trusted to accurately classify immunogenicity samples?

    Jaki, T. F., Allacher, P. & Horling, F., 5/09/2016, In: Journal of Pharmaceutical and Biomedical Analysis. 128, p. 166-173 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Tilting the lasso by knowledge-based post-processing

    Tharmaratnam, K., Sperrin, M., Jaki, T. F., Reppe, S. & Frigessi, A., 2/09/2016, In: BMC Bioinformatics. 17, 9 p., 344.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Understanding clinical prediction models as ‘innovations’: a mixed methods study in UK family practice

    Brown, B., Cheraghi-Sohi, S., Jaki, T. F., Su, T-L., Buchan, I. & Sperrin, M., 9/08/2016, In: BMC Medical Informatics and Decision Making. 16, 13 p., 106.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    Why are two mistakes not worse than one? a proposal for controlling the expected number of false claims

    Jaki, T. F. & Parry, A., 07/2016, In: Pharmaceutical Statistics. 15, 4, p. 362-367 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    A review of statistical designs for improving the efficiency of phase II studies in oncology

    Wason, J. & Jaki, T., 06/2016, In: Statistical Methods in Medical Research. 25, 3, p. 1010-1021 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Impact of an equality constraint on the class-specific residual variances in regression mixtures: a Monte Carlo simulation study

    Kim, M., Lamont, A. E., Jaki, T., Feaster, D., Howe, G. & Van Horn, M. L., 06/2016, In: Behavior Research Methods. 48, 2, p. 813-826 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Modeling predictors of latent classes in regression mixture models

    Kim, M., Vermunt, J., Bakk, Z., Jaki, T. F. & Van Horn, M. L., 06/2016, In: Structural Equation Modeling. 23, 4, p. 601-614 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Some recommendations for multi-arm multi-stage trials

    Wason, J., Magirr, D., Law, M. & Jaki, T., 04/2016, In: Statistical Methods in Medical Research. 25, 2, p. 716-727 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Designing multi-arm multi-stage clinical trials using a risk-benefit criterion for treatment selection

    Jaki, T. & Hampson, L., 20/02/2016, In: Statistics in Medicine. 35, 4, p. 522-533 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Sample size reassessment and hypothesis testing in adaptive survival trials

    Magirr, D., Jaki, T. F., Koenig, F. & Posch, M., 10/02/2016, In: PLoS ONE. 11, 2, 14 p., e0146465.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Using multilevel regression mixture models to identify level-1 heterogeneity in level-2 effects

    Van Horn, M. L., Feng, Y., Kim, M., Lamont, A. E., Feaster, D. & Jaki, T., 2016, In: Structural Equation Modeling. 23, 2, p. 259-269 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. 2015
  14. Published

    Bayesian adaptive dose-escalation procedures for binary and continuous responses utilizing a gain function

    Yeung, W. Y., Whitehead, J. R., Reigner, B., Beyer, U., Diack, C. & Jaki, T. F., 11/2015, In: Pharmaceutical Statistics. 14, 6, p. 479-487 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Telmisartan and Insulin Resistance in HIV (TAILoR): protocol for a dose-ranging phase II randomised open-labelled trial of Telmisartan as a strategy for the reduction of insulin resistance in HIV-positive individuals on combination antiretroviral therapy

    Pushpakom, S. P., Taylor, C., Kolamunnage-Dona, R., Spowart, C., Vora, J., Garcıa-Finana, M., Kemp, G. J., Whitehead, J., Jaki, T., Khoo, S., Williamson, P. & Pirmohamed, M., 15/10/2015, In: BMJ Open. 5, 10, 13 p., e009566.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    Evaluating differential effects using regression interactions and regression mixture models

    Van Horn, M. L., Jaki, T., Maysn, K., Howe, G., Feaster, D., Lamont, A. E., George, M. & Kim, M., 08/2015, In: Educational and Psychological Measurement. 75, 4, p. 677-714 38 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    A practical design for a dual-agent dose-escalation trial that incorporates pharmacokinetic data

    Cotterill, A., Lorand, D., Wang, J. & Jaki, T., 15/06/2015, In: Statistics in Medicine. 34, 13, p. 2138-2164 27 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    Adaptive clinical trials in tuberculosis: applications, challenges and solutions

    Davis, G. R., Phillips, P. P. & Jaki, T., 1/06/2015, In: International Journal of Tuberculosis and Lung Disease. 19, 6, p. 626-634 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    Multi-arm clinical trials with treatment selection: what can be gained and at what price?

    Jaki, T., 04/2015, In: Clinical Investigation. 5, 4, p. 393-399 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. Published

    Statistical approaches for the determination of cut points in anti-drug antibody bioassays

    Schaarschmidt, F., Hofmann, M., Jaki, T., Gruen, B. & Hothorn, L. A., 03/2015, In: Journal of Immunological Methods. 418, p. 84-100 17 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. 2014
  22. Published

    Flexible sequential designs for multi-arm clinical trials

    Magirr, D., Stallard, N. & Jaki, T., 30/08/2014, In: Statistics in Medicine. 33, 19, p. 3269-3279 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    A comparison of methods for classifying samples as truly specific with confirmatory immunoassays

    Jaki, T., Lawo, J-P., Wolfsegger, M. J., Allacher, P. & Horling, F., 25/01/2014, In: Journal of Pharmaceutical and Biomedical Analysis. 88, p. 27-35 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    A hybrid method to estimate the minimum effective dose for monotone and non-monotone dose-response relationships

    Wolfsegger, M. J., Gutjahr, G., Engl, W. & Jaki, T., 2014, In: Biometrics. 70, 1, p. 103-109 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    Designing multi-arm multi-stage clinical studies

    Jaki, T., 2014, Developments in statistical evaluation of clinical trials. van Montfort, K., Oud, J. & Ghidey, W. (eds.). Berlin: Springer, p. 51-69 19 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter (peer-reviewed) › peer-review

  26. Published

    Statistical evaluation of toxicological assays with zero or near-to-zero proportions or counts in the concurrent negative control group: a tutorial

    Jaki, T., Kitsche, A. & Hothorn, L. A., 2014, In: JP Journal of Biostatistics. 11, 1, p. 1-32 32 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  27. 2013
  28. Published

    Authors' reply to comments on "Estimation in AB/BA cross-over trials with application to bioequivalence studies with incomplete and complete data settings"

    Jaki, T., Pallmann, P. & Wolfsegger, M. J., 30/12/2013, In: Statistics in Medicine. 32, 30, p. 5487-5488 2 p.

    Research output: Contribution to Journal/Magazine › Comment/debate

  29. Published

    Estimation in AB/BA cross-over trials with application to bioequivalence studies with incomplete and complete data designs

    Jaki, T., Pallmann, P. & Wolfsegger, M. J., 30/12/2013, In: Statistics in Medicine. 32, 30, p. 5469-5483 15 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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