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Professor Thomas Jaki

Formerly at Lancaster University

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  1. Journal article
  2. Published

    Why are two mistakes not worse than one? a proposal for controlling the expected number of false claims

    Jaki, T. F. & Parry, A., 07/2016, In: Pharmaceutical Statistics. 15, 4, p. 362-367 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    A review of statistical designs for improving the efficiency of phase II studies in oncology

    Wason, J. & Jaki, T., 06/2016, In: Statistical Methods in Medical Research. 25, 3, p. 1010-1021 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Impact of an equality constraint on the class-specific residual variances in regression mixtures: a Monte Carlo simulation study

    Kim, M., Lamont, A. E., Jaki, T., Feaster, D., Howe, G. & Van Horn, M. L., 06/2016, In: Behavior Research Methods. 48, 2, p. 813-826 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    Modeling predictors of latent classes in regression mixture models

    Kim, M., Vermunt, J., Bakk, Z., Jaki, T. F. & Van Horn, M. L., 06/2016, In: Structural Equation Modeling. 23, 4, p. 601-614 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Some recommendations for multi-arm multi-stage trials

    Wason, J., Magirr, D., Law, M. & Jaki, T., 04/2016, In: Statistical Methods in Medical Research. 25, 2, p. 716-727 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Designing multi-arm multi-stage clinical trials using a risk-benefit criterion for treatment selection

    Jaki, T. & Hampson, L., 20/02/2016, In: Statistics in Medicine. 35, 4, p. 522-533 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Sample size reassessment and hypothesis testing in adaptive survival trials

    Magirr, D., Jaki, T. F., Koenig, F. & Posch, M., 10/02/2016, In: PLoS ONE. 11, 2, 14 p., e0146465.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Using multilevel regression mixture models to identify level-1 heterogeneity in level-2 effects

    Van Horn, M. L., Feng, Y., Kim, M., Lamont, A. E., Feaster, D. & Jaki, T., 2016, In: Structural Equation Modeling. 23, 2, p. 259-269 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Bayesian adaptive dose-escalation procedures for binary and continuous responses utilizing a gain function

    Yeung, W. Y., Whitehead, J. R., Reigner, B., Beyer, U., Diack, C. & Jaki, T. F., 11/2015, In: Pharmaceutical Statistics. 14, 6, p. 479-487 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Telmisartan and Insulin Resistance in HIV (TAILoR): protocol for a dose-ranging phase II randomised open-labelled trial of Telmisartan as a strategy for the reduction of insulin resistance in HIV-positive individuals on combination antiretroviral therapy

    Pushpakom, S. P., Taylor, C., Kolamunnage-Dona, R., Spowart, C., Vora, J., Garcıa-Finana, M., Kemp, G. J., Whitehead, J., Jaki, T., Khoo, S., Williamson, P. & Pirmohamed, M., 15/10/2015, In: BMJ Open. 5, 10, 13 p., e009566.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Evaluating differential effects using regression interactions and regression mixture models

    Van Horn, M. L., Jaki, T., Maysn, K., Howe, G., Feaster, D., Lamont, A. E., George, M. & Kim, M., 08/2015, In: Educational and Psychological Measurement. 75, 4, p. 677-714 38 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    A practical design for a dual-agent dose-escalation trial that incorporates pharmacokinetic data

    Cotterill, A., Lorand, D., Wang, J. & Jaki, T., 15/06/2015, In: Statistics in Medicine. 34, 13, p. 2138-2164 27 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Adaptive clinical trials in tuberculosis: applications, challenges and solutions

    Davis, G. R., Phillips, P. P. & Jaki, T., 1/06/2015, In: International Journal of Tuberculosis and Lung Disease. 19, 6, p. 626-634 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Multi-arm clinical trials with treatment selection: what can be gained and at what price?

    Jaki, T., 04/2015, In: Clinical Investigation. 5, 4, p. 393-399 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    Statistical approaches for the determination of cut points in anti-drug antibody bioassays

    Schaarschmidt, F., Hofmann, M., Jaki, T., Gruen, B. & Hothorn, L. A., 03/2015, In: Journal of Immunological Methods. 418, p. 84-100 17 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    Flexible sequential designs for multi-arm clinical trials

    Magirr, D., Stallard, N. & Jaki, T., 30/08/2014, In: Statistics in Medicine. 33, 19, p. 3269-3279 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    A comparison of methods for classifying samples as truly specific with confirmatory immunoassays

    Jaki, T., Lawo, J-P., Wolfsegger, M. J., Allacher, P. & Horling, F., 25/01/2014, In: Journal of Pharmaceutical and Biomedical Analysis. 88, p. 27-35 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    A hybrid method to estimate the minimum effective dose for monotone and non-monotone dose-response relationships

    Wolfsegger, M. J., Gutjahr, G., Engl, W. & Jaki, T., 2014, In: Biometrics. 70, 1, p. 103-109 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. Published

    Statistical evaluation of toxicological assays with zero or near-to-zero proportions or counts in the concurrent negative control group: a tutorial

    Jaki, T., Kitsche, A. & Hothorn, L. A., 2014, In: JP Journal of Biostatistics. 11, 1, p. 1-32 32 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. Published

    Estimation in AB/BA cross-over trials with application to bioequivalence studies with incomplete and complete data designs

    Jaki, T., Pallmann, P. & Wolfsegger, M. J., 30/12/2013, In: Statistics in Medicine. 32, 30, p. 5469-5483 15 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. Published

    Statistical evaluation of toxicological assays: Dunnett or Williams test? − take both

    Jaki, T. & Hothorn, L. A., 11/2013, In: Archives of Toxicology. 87, 11, p. 1901-1910 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    Planning multi-arm screening studies within the context of a drug development programme

    Wason, J., Jaki, T. & Stallard, N., 10/09/2013, In: Statistics in Medicine. 32, 20, p. 3424-3435 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    Differential effects of parental controls on adolescent substance use: for whom is the family most important?

    Fagan, A. A., Van Horn, M. L., Hawkins, J. D. & Jaki, T., 09/2013, In: Journal of Quantitative Criminology. 29, 3, p. 347-368 22 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    Multiplicity: discussion points from the PSI multiplicity expert group

    Phillips, A., Fletcher, C., Atkinson, G., Channon, E., Douiri, A., Jaki, T., Maca, J., Morgan, D., Roger, J. H. & Terrill, P., 09/2013, In: Pharmaceutical Statistics. 12, 5, p. 255-259 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  26. Published

    Analysing malaria drug trials on a per individual or a per clone basis: a comparison of methods

    Jaki, T., Parry, A., Winter, K. & Hastings, I., 30/07/2013, In: Statistics in Medicine. 32, 17, p. 3020-3038 19 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  27. Published

    Designing exploratory cancer trials using change in tumour size as primary endpoint

    Jaki, T., Andre, V., Su, T-L. & Whitehead, J., 10/07/2013, In: Statistics in Medicine. 32, 15, p. 2544-2554 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  28. Published

    Principles of dose finding studies in cancer: a comparison of trial designs

    Jaki, T., Clive, S. & Weir, C., 05/2013, In: Cancer Chemotherapy and Pharmacology. 71, 5, p. 1107-1114 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  29. Published

    Uptake of novel statistical methods for early phase clinical studies in the UK public sector

    Jaki, T., 04/2013, In: Clinical Trials. 10, 2, p. 344-346 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  30. Published

    Considerations on covariates and endpoints in multi-arm multi-stage clinical trials selecting all promising treatments

    Jaki, T. & Magirr, D., 30/03/2013, In: Statistics in Medicine. 32, 7, p. 1150-1163 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  31. Published

    Using regression mixture models with non-normal data: examining an ordered polytomous approach

    George, M., Yang, N., Van Horn, M. L., Smith, J., Jaki, T., Feaster, D., Maysn, K. & Howe, G., 2013, In: Journal of Statistical Computation and Simulation. 83, 4, p. 757-770 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  32. Published

    Simultaneous confidence intervals that are compatible with closed testing in adaptive designs

    Magirr, D., Jaki, T., Posch, M. & Klingelmueller, F., 2013, In: Biometrika. 100, 4, p. 985-996 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  33. Published

    Finite mixtures for simultaneously modelling differential effects and non-normal distributions

    George, M., Yang, N., Jaki, T., Feaster, D., Lamont, A. E., Van Horn, M. L. & Wilson, D. K., 2013, In: Multivariate Behavioral Research. 48, 6, p. 816-844 29 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  34. Published

    Optimal design of multi-arm multi-stage trials

    Wason, J. & Jaki, T., 30/12/2012, In: Statistics in Medicine. 31, 30, p. 4269-4279 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  35. Published

    A novel phase I/IIa design for early phase oncology studies and its application in the evaluation of MK-0752 in pancreatic cancer

    Whitehead, J., Thygesen, H., Jaki, T., Davis, S., Halford, S., Turner, H., Cook, N. & Jodrell, D., 15/08/2012, In: Statistics in Medicine. 31, 18, p. 1931-1943 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  36. Published

    Recovering Independent Associations in Genetics: A Comparison

    Sperrin, M. & Jaki, T., 08/2012, In: Journal of Computational Biology. 19, 8, p. 978–987 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  37. Published

    A generalized Dunnett Test for Multi-arm Multi-stage Clinical Studies with Treatment Selection

    Magirr, D., Jaki, T. & Whitehead, J., 06/2012, In: Biometrika. 99, 2, p. 494-501 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  38. Published

    Not quite normal: Consequences of violating the assumption of normality with regression mixture models

    Van Horn, M. L., Smith, J., Fagan, A., Jaki, T., Maysn, K., Hawkins, D., Feaster, D. & Howe, G., 2012, In: Structural Equation Modeling. 19, 2, p. 227-249 23 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  39. Published

    Non-compartmental estimation of pharmacokinetic parameters for flexible sampling designs

    Jaki, T. & Wolfsegger, M. J., 2012, In: Statistics in Medicine. 31, 11-12, p. 1059-1073 25 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  40. Published

    A formal comparison of different methods for establishing cut points to distinguish positive and negative samples in immunoassays.

    Jaki, T., Lawo, J-P., Wolfsegger, M. J., Singer, J., Allacher, P. & Horling, F., 15/07/2011, In: Journal of Pharmaceutical and Biomedical Analysis. 55, 5, p. 1148-1156 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  41. Published

    Estimation of pharmacokinetic parameters with the R package PK.

    Jaki, T. & Wolfsegger, M. J., 05/2011, In: Pharmaceutical Statistics. 10, 2, p. 284-288 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  42. Published

    Symmetric maximum kernel likelihood estimation.

    Jaki, T. & West, R. W., 02/2011, In: Journal of Statistical Computation and Simulation. 81, 2, p. 193-206 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  43. Published

    Direct effects testing : a two-stage procedure to test for effect size and variable importance for correlated binary predictors and a binary response.

    Sperrin, M. & Jaki, T., 30/10/2010, In: Statistics in Medicine. 29, 24, p. 2544-2556 13 p.

    Research output: Contribution to Journal/Magazine › Journal article

  44. Published

    Establishing bioequivalence in complete and incomplete data designs using AUCs.

    Jaki, T., Wolfsegger, M. J. & Lawo, J-P., 07/2010, In: Journal of Biopharmaceutical Statistics. 20, 4, p. 803-820 18 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  45. Published

    Probabilistic relabelling strategies for the label switching problem in Bayesian mixture models.

    Sperrin, M., Jaki, T. & Wit, E., 07/2010, In: Statistics and Computing. 20, 3, p. 357-366 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  46. Published

    Optimization, refinement and reduction of murine in vivo experiments to assess therapeutic approaches for hemophilia A.

    Baumgartner, B., Jaki, T., Wolfsegger, M. J., Eder, B., Schiviz, A., Schwarz, H. P. & Muchitsch, E. M., 07/2010, In: Laboratory Animals. 44, 3, p. 211-217 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  47. Published

    Assessing systemic drug exposure in repeated dose toxicity studies in the case of complete and incomplete sampling.

    Wolfsegger, M. J. & Jaki, T., 12/2009, In: Biometrical Journal. 51, 6, p. 1017-1026 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  48. Published

    Recording lectures as a service in a service course.

    Jaki, T., 11/2009, In: Journal of Statistics Education. 17, 3

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  49. Published

    A note on statistical analysis of organ weights in non-clinical toxicological studies.

    Wolfsegger, M. J., Jaki, T., Dietrich, B., Kunzler, J. A. & Barker, K., 10/2009, In: Toxicology and Applied Pharmacology. 240, 1, p. 117-122 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  50. Published

    Non-compartmental estimation of pharmacokinetic parameters in serial sampling designs.

    Wolfsegger, M. J. & Jaki, T., 10/2009, In: Journal of Pharmacokinetics and Pharmacodynamics. 36, 5, p. 479-494

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  51. Published

    Assessing differential effects: Applying regression mixture models to identify variations in the influence of family resources on academic achievement.

    Van Horn, M. L., Jaki, T., Maysn, K., Ramey, S. L., Smith, J. A. & Antaramian, S., 09/2009, In: Developmental Psychology. 45, 5, p. 1298-1313 16 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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