Thomas Jaki - Publications & Outputs - Research Portal

Professor Thomas Jaki

Formerly at Lancaster University

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Journal article
Published
Designing exploratory cancer trials using change in tumour size as primary endpoint
Jaki, T., Andre, V., Su, T-L. & Whitehead, J., 10/07/2013, In: Statistics in Medicine. 32, 15, p. 2544-2554 11 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Principles of dose finding studies in cancer: a comparison of trial designs
Jaki, T., Clive, S. & Weir, C., 05/2013, In: Cancer Chemotherapy and Pharmacology. 71, 5, p. 1107-1114 8 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Uptake of novel statistical methods for early phase clinical studies in the UK public sector
Jaki, T., 04/2013, In: Clinical Trials. 10, 2, p. 344-346 3 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Considerations on covariates and endpoints in multi-arm multi-stage clinical trials selecting all promising treatments
Jaki, T. & Magirr, D., 30/03/2013, In: Statistics in Medicine. 32, 7, p. 1150-1163 14 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Using regression mixture models with non-normal data: examining an ordered polytomous approach
George, M., Yang, N., Van Horn, M. L., Smith, J., Jaki, T., Feaster, D., Maysn, K. & Howe, G., 2013, In: Journal of Statistical Computation and Simulation. 83, 4, p. 757-770 14 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Simultaneous confidence intervals that are compatible with closed testing in adaptive designs
Magirr, D., Jaki, T., Posch, M. & Klingelmueller, F., 2013, In: Biometrika. 100, 4, p. 985-996 12 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Finite mixtures for simultaneously modelling differential effects and non-normal distributions
George, M., Yang, N., Jaki, T., Feaster, D., Lamont, A. E., Van Horn, M. L. & Wilson, D. K., 2013, In: Multivariate Behavioral Research. 48, 6, p. 816-844 29 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Optimal design of multi-arm multi-stage trials
Wason, J. & Jaki, T., 30/12/2012, In: Statistics in Medicine. 31, 30, p. 4269-4279 11 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
A novel phase I/IIa design for early phase oncology studies and its application in the evaluation of MK-0752 in pancreatic cancer
Whitehead, J., Thygesen, H., Jaki, T., Davis, S., Halford, S., Turner, H., Cook, N. & Jodrell, D., 15/08/2012, In: Statistics in Medicine. 31, 18, p. 1931-1943 13 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Recovering Independent Associations in Genetics: A Comparison
Sperrin, M. & Jaki, T., 08/2012, In: Journal of Computational Biology. 19, 8, p. 978–987 10 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
A generalized Dunnett Test for Multi-arm Multi-stage Clinical Studies with Treatment Selection
Magirr, D., Jaki, T. & Whitehead, J., 06/2012, In: Biometrika. 99, 2, p. 494-501 8 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Not quite normal: Consequences of violating the assumption of normality with regression mixture models
Van Horn, M. L., Smith, J., Fagan, A., Jaki, T., Maysn, K., Hawkins, D., Feaster, D. & Howe, G., 2012, In: Structural Equation Modeling. 19, 2, p. 227-249 23 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Non-compartmental estimation of pharmacokinetic parameters for flexible sampling designs
Jaki, T. & Wolfsegger, M. J., 2012, In: Statistics in Medicine. 31, 11-12, p. 1059-1073 25 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
A formal comparison of different methods for establishing cut points to distinguish positive and negative samples in immunoassays.
Jaki, T., Lawo, J-P., Wolfsegger, M. J., Singer, J., Allacher, P. & Horling, F., 15/07/2011, In: Journal of Pharmaceutical and Biomedical Analysis. 55, 5, p. 1148-1156 9 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Estimation of pharmacokinetic parameters with the R package PK.
Jaki, T. & Wolfsegger, M. J., 05/2011, In: Pharmaceutical Statistics. 10, 2, p. 284-288 5 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Symmetric maximum kernel likelihood estimation.
Jaki, T. & West, R. W., 02/2011, In: Journal of Statistical Computation and Simulation. 81, 2, p. 193-206 14 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Direct effects testing : a two-stage procedure to test for effect size and variable importance for correlated binary predictors and a binary response.
Sperrin, M. & Jaki, T., 30/10/2010, In: Statistics in Medicine. 29, 24, p. 2544-2556 13 p.
Research output: Contribution to Journal/Magazine › Journal article
Published
Establishing bioequivalence in complete and incomplete data designs using AUCs.
Jaki, T., Wolfsegger, M. J. & Lawo, J-P., 07/2010, In: Journal of Biopharmaceutical Statistics. 20, 4, p. 803-820 18 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Probabilistic relabelling strategies for the label switching problem in Bayesian mixture models.
Sperrin, M., Jaki, T. & Wit, E., 07/2010, In: Statistics and Computing. 20, 3, p. 357-366 10 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Optimization, refinement and reduction of murine in vivo experiments to assess therapeutic approaches for hemophilia A.
Baumgartner, B., Jaki, T., Wolfsegger, M. J., Eder, B., Schiviz, A., Schwarz, H. P. & Muchitsch, E. M., 07/2010, In: Laboratory Animals. 44, 3, p. 211-217 7 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Assessing systemic drug exposure in repeated dose toxicity studies in the case of complete and incomplete sampling.
Wolfsegger, M. J. & Jaki, T., 12/2009, In: Biometrical Journal. 51, 6, p. 1017-1026 10 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Recording lectures as a service in a service course.
Jaki, T., 11/2009, In: Journal of Statistics Education. 17, 3
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
A note on statistical analysis of organ weights in non-clinical toxicological studies.
Wolfsegger, M. J., Jaki, T., Dietrich, B., Kunzler, J. A. & Barker, K., 10/2009, In: Toxicology and Applied Pharmacology. 240, 1, p. 117-122 6 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Non-compartmental estimation of pharmacokinetic parameters in serial sampling designs.
Wolfsegger, M. J. & Jaki, T., 10/2009, In: Journal of Pharmacokinetics and Pharmacodynamics. 36, 5, p. 479-494
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Published
Assessing differential effects: Applying regression mixture models to identify variations in the influence of family resources on academic achievement.
Van Horn, M. L., Jaki, T., Maysn, K., Ramey, S. L., Smith, J. A. & Antaramian, S., 09/2009, In: Developmental Psychology. 45, 5, p. 1298-1313 16 p.
Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Research

Professor Thomas Jaki

Designing exploratory cancer trials using change in tumour size as primary endpoint

Principles of dose finding studies in cancer: a comparison of trial designs

Uptake of novel statistical methods for early phase clinical studies in the UK public sector

Considerations on covariates and endpoints in multi-arm multi-stage clinical trials selecting all promising treatments

Using regression mixture models with non-normal data: examining an ordered polytomous approach

Simultaneous confidence intervals that are compatible with closed testing in adaptive designs

Finite mixtures for simultaneously modelling differential effects and non-normal distributions

Optimal design of multi-arm multi-stage trials

A novel phase I/IIa design for early phase oncology studies and its application in the evaluation of MK-0752 in pancreatic cancer

Recovering Independent Associations in Genetics: A Comparison

A generalized Dunnett Test for Multi-arm Multi-stage Clinical Studies with Treatment Selection

Not quite normal: Consequences of violating the assumption of normality with regression mixture models

Non-compartmental estimation of pharmacokinetic parameters for flexible sampling designs

A formal comparison of different methods for establishing cut points to distinguish positive and negative samples in immunoassays.

Estimation of pharmacokinetic parameters with the R package PK.

Symmetric maximum kernel likelihood estimation.

Direct effects testing : a two-stage procedure to test for effect size and variable importance for correlated binary predictors and a binary response.

Establishing bioequivalence in complete and incomplete data designs using AUCs.

Probabilistic relabelling strategies for the label switching problem in Bayesian mixture models.

Optimization, refinement and reduction of murine in vivo experiments to assess therapeutic approaches for hemophilia A.

Assessing systemic drug exposure in repeated dose toxicity studies in the case of complete and incomplete sampling.

Recording lectures as a service in a service course.

A note on statistical analysis of organ weights in non-clinical toxicological studies.

Non-compartmental estimation of pharmacokinetic parameters in serial sampling designs.

Assessing differential effects: Applying regression mixture models to identify variations in the influence of family resources on academic achievement.

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