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Dr Timothy Douglas

Lecturer in Bio-Chemical Engineering

  1. 2012
  2. Published

    Enzymatic Mineralization of Hydrogels for Bone Tissue Engineering by Incorporation of Alkaline Phosphatase

    Douglas, T. E. L., Messersmith, P. B., Chasan, S., Mikos, A. G., de Mulder, E. L. W., Dickson, G., Schaubroeck, D., Balcaen, L., Vanhaecke, F., Dubruel, P., Jansen, J. A. & Leeuwenburgh, S. C. G., 08/2012, In: Macromolecular Bioscience. 12, 8, p. 1077-1089 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. 2013
  4. Published

    Acceleration of gelation and promotion of mineralization of chitosan hydrogels by alkaline phosphatase

    Douglas, T. E. L., Skwarczynska, A., Modrzejewska, Z., Balcaen, L., Schaubroeck, D., Lycke, S., Vanhaecke, F., Vandenabeele, P., Dubruel, P., Jansen, J. A. & Leeuwenburgh, S. C. G., 05/2013, In: International Journal of Biological Macromolecules. 56, p. 122-132 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. 2014
  6. Published

    Enrichment of chitosan hydrogels with perfluorodecalin promotes gelation and stem cell vitality

    Douglas, T. E. L., Pilarek, M., Kalaszczynska, I., Senderek, I., Skwarczynska, A., Cuijpers, V. M. J. I., Modrzejewska, Z., Lewandowska-Szumiel, M. & Dubruel, P., 1/08/2014, In: Materials Letters. 128, p. 79-84 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Enzymatic mineralization of gellan gum hydrogel for bone tissue-engineering applications and its enhancement by polydopamine

    Douglas, T. E. L., Wlodarczyk, M., Pamula, E., Declercq, H., de Mulder, E., Bucko, M., Balcaen, L., Vanhaecke, F., Cornelissen, R., Dubruel, P., Jansen, J. & Leeuwenburgh, S., 1/11/2014, In: Journal of Tissue Engineering and Regenerative Medicine. 8, 11, p. 906-918 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. 2015
  9. Published

    Pulsed laser deposition of magnesium-doped calcium phosphate coatings on porous polycaprolactone scaffolds produced by rapid prototyping

    Vandrovcova, M., Douglas, T. E. L., Mróz, W., Musial, O., Schaubroeck, D., Budner, B., Syroka, R., Dubruel, P. & Bacakova, L., 23/02/2015, In: Materials Letters. 148, p. 178-183 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    Development of Thermosensitive Hydrogels of Chitosan, Sodium and Magnesium Glycerophosphate for Bone Regeneration Applications

    Liskova, J., Bacakova, L., Skwarczynska, A. L., Musial, O., Bliznuk, V., De Schamphelaere, K., Modrzejewska, Z. & Douglas, T. E. L., 06/2015, In: Journal of Functional Biomaterials. 6, 2, p. 192-203 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    Chitosan hydrogels enriched with polyphenols: Antibacterial activity, cell adhesion and growth and mineralization

    Liskova, J., Douglas, T. E. L., Beranova, J., Skwarczynska, A., Bozic, M., Samal, S. K., Modrzejewska, Z., Gorgieva, S., Kokol, V. & Bacakova, L., 20/09/2015, In: Carbohydrate Polymers. 129, p. 135-142 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. 2016
  13. Published

    Enrichment of enzymatically mineralized gellan gum hydrogels with phlorotannin-rich Ecklonia cava extract Seanol(®) to endow antibacterial properties and promote mineralization

    Douglas, T. E. L., Dokupil, A., Reczyńska, K., Brackman, G., Krok-Borkowicz, M., Keppler, J. K., Božič, M., Van Der Voort, P., Pietryga, K., Samal, S. K., Balcaen, L., van den Bulcke, J., Van Acker, J., Vanhaecke, F., Schwarz, K., Coenye, T. & Pamuła, E., 10/08/2016, In: Biomedical Materials. 11, 4, 13 p., 045015.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Generation of composites for bone tissue-engineering applications consisting of gellan gum hydrogels mineralized with calcium and magnesium phosphate phases by enzymatic means

    Douglas, T. E. L., Krawczyk, G., Pamula, E., Declercq, H., Schaubroeck, D., Bucko, M., Balcaen, L., Van der Voort, P., Bliznuk, V., van den Vreken, N., Dash, M., Detsch, R., Boccaccini, A., Vanhaecke, F., Cornelissen, R. & Dubruel, 11/2016, In: Journal of Tissue Engineering and Regenerative Medicine. 10, 11, p. 938-954 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. 2017
  16. Published

    Vaterite coatings on electrospun polymeric fibers for biomedical applications

    Savelyeva, M. S., Abalymov, A. A., Lyubun, G. P., Vidyasheva, I. V., Yashchenok, A. M., Douglas, T. E. L., Gorin, D. A. & Parakhonskiy, B. V., 1/01/2017, In: Journal of Biomedical Materials Research Part A. p. 94-103 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Ca:Mg:Zn:CO3 and Ca:Mg:CO3-tri- and bi-elemental carbonate microparticles for novel injectable self-gelling hydrogel-microparticle composites for tissue regeneration

    Douglas, T. E. L., Sobczyk, K., Łapa, A., Włodarczyk, K., Brackman, G., Vidiasheva, I., Reczyńska, K., Pietryga, K., Schaubroeck, D., Bliznuk, V., Van Der Voort, P., Declercq, H., Van den Bulcke, J., Samal, S. K., Khalenkow, D., Parakhonskiy, B., Van Acker, J., Coenye, T., Lewandowska-Szumieł, M., Pamuła, E., & 1 othersSkirtach, A., 24/03/2017, In: Biomedical Materials. 12, 2, 13 p., 025015.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Composites of gellan gum hydrogel enzymatically mineralized with calcium-zinc phosphate for bone regeneration with antibacterial activity.

    Douglas, T. E. L., Pilarz, M., Lopez-Heredia, M., Brackman, G., Schaubroeck, D., Balcaen, L., Bliznuk, V., Dubruel, P., Knabe-Ducheyne, Vanhaecke, F., Coenye, T. & Pamula, E., 05/2017, In: Journal of Tissue Engineering and Regenerative Medicine. 11, 5, p. 1610-1618 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. Published

    Enzymatically biomineralized chitosan scaffolds for tissue-engineering applications

    Dash, M., Samal, S. K., Douglas, T. E. L., Schaubroeck, D., Leeuwenburgh, S. C., Voort, P. V. D., Declercq, H. A. & Dubruel, P., 1/05/2017, In: Journal of Tissue Engineering and Regenerative Medicine. 11, 5, p. 1500-1513 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    Titanium surface functionalization with coatings of chitosan and polyphenol-rich plant extracts

    Douglas, T. E. L., Kumari, S., Dziadek, K., Dziadek, M., Abalymov, A., Cools, P., Brackman, G., Coenye, T., Morent, R., Mohan, M. K. & Skirtach, A. G., 1/06/2017, In: Materials Letters. 196, p. 213-216 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    Enzymatic, urease-mediated mineralization of gellan gum hydrogel with calcium carbonate, magnesium-enriched calcium carbonate and magnesium carbonate for bone regeneration applications.

    Douglas, T. E. L., Lapa, A., Samal, S., Declercq, H., Declercq, H., Schaubroeck, D., Mendes, A., Van der Voort, P., Dokupil, A., Plis, A., De Schamphelaere, K., Chronakis, I., Pamula, E. & Skirtach, A., 12/2017, In: Journal of Tissue Engineering and Regenerative Medicine. p. 3556-3566 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. 2018
  23. Published

    Application of whey protein isolate in bone regeneration: Effects on growth and osteogenic differentiation of bone-forming cells

    Douglas, T. E. L., Vandrovcová, M., Kročilová, N., Keppler, J. K., Zárubová, J., Skirtach, A. G. & Bačáková, L., 01/2018, In: Journal of Dairy Science. 101, 1, p. 28-36 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Ulvan-chitosan polyelectrolyte complexes as matrices for enzyme induced biomimetic mineralization

    Dash, M., Samal, S. K., Morelli, A., Bartoli, C., Declercq, H. A., Douglas, T. E. L., Dubruel, P. & Chiellini, F., 15/02/2018, In: Carbohydrate Polymers. 182, p. 254-264 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    Novel self-gelling injectable hydrogel/alpha-tricalcium phosphate composites for bone regeneration: Physiochemical and microcomputer tomographical characterization

    Douglas, T. E. L., Schietse, J., Zima, A., Gorodzha, S., Parakhonskiy, B., Khalenkow, D., Shkarin, R., Ivanova, A., Baumbach, T., Weinhardt, V., Stevens, C., Vanhoorne, V., Vervaet, C., Balcaen, L., Vanhaecke, F., Slosarczyk, A., Surmeneva, M., Surmenev, R. & Skirtach, A., 03/2018, In: Journal of Biomedical Materials Research Part A. 106, 3, p. 822-828 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  26. Published

    Phytase-mediated enzymatic mineralization of chitosan-enriched hydrogels

    Lišková, J., Douglas, T. E. L., Wijnants, R., Samal, S. K., Mendes, A. C., Chronakis, I., Bačáková, L. & Skirtach, A. G., 1/03/2018, In: Materials Letters. 214, p. 186-189 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  27. Published

    Novel injectable gellan gum hydrogel composites incorporating Zn- and Sr-enriched bioactive glass microparticles: high-resolution X-Ray micro-computed tomography, antibacterial and in vitro testing

    Douglas, T. E. L., Dziadek, M., Gorodzha, S., Liskova, J., Brackman, G., Vanhoorne, V., Vervaet, C., Balcaen, L., del Rosario Florez Garcia, M., Boccaccini, A., Weinhardt, V., Baumbach, T., Vanhaecke, F., Coenye, T., Bacakova, L., Surmeneva, M., Surmenev, R., Cholewa-Kowalska, K. & Skirtach, A., 06/2018, In: Journal of Tissue Engineering and Regenerative Medicine. 12, 6, p. 1313-1326 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  28. Published

    Mineralization of gellan gum hydrogels with calcium and magnesium carbonates by alternate soaking for bone regeneration applications

    Lopez-Heredia, M., Lapa, A., Reczynska, K., Pietryga, K., Balcaen, L., Mendes, A., Schaubroeck, D., Van der Voort, P., Dokupil, A., Plis, A., Stevens, C., Parakhonskiy, B., Samal, S., Vanhaecke, F., Chai, F., Chronakis, I., Blanchemain, N., Pamula, E., Skirtach, A. G. & Douglas, T. E. L., 08/2018, In: Journal of Tissue Engineering and Regenerative Medicine. 12, 8, p. 1825-1834 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  29. Published

    Morphological, mechanical and mucoadhesive properties of electrospun chitosan/phospholipid hybrid nanofibers

    Mendes, A. C., Moreno, J. S., Hanif, M., Douglas, T. E. L., Chen, M. & Chronakis, I. S., 2/08/2018, In: International Journal of Molecular Sciences. 19, 8, 16 p., 2266.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  30. Published

    Pectin coatings on titanium alloy scaffolds produced by additive manufacturing: Promotion of human bone marrow stromal cell proliferation

    Douglas, T. E. L., Hempel, U., Zydek, J., Vladescu, A., Pietryga, K., Kaeswurm, J., Buchweitz, M., Surmenev, R., Surmeneva, M., Cotrut, C., Koptyug, A. & Pamula, E., 15/09/2018, In: Materials Letters. 227, p. 225-228 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  31. Published

    Electrospun Produced 3D Matrices for Covering of Vascular Stents: Paclitaxel Release Depending on Fiber Structure and Composition of the External Environment

    Kuznetsov, K., Stepanova, A., Kvon, R., Douglas, T. E. L., Kuznetsov, N., Chernonosova, V., Zaporozhchenko, I., Kharkova, M., Romanova, I., Karpenko, A. & Laktionov, P., 2/11/2018, In: Materials. 11, 11, 16 p., 2176.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  32. Published

    ANN prediction of corrosion behaviour of uncoated and biopolymers coated cp-Titanium substrates

    Kumari, S., Tiyyagura, H. R., Douglas, T. E. L., Mohammed, E. A. A., Adriaens, A., Fuchs-Godec, R., Mohan, M. K. & Skirtach, A. G., 5/11/2018, In: Materials and Design. 157, p. 35-51 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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