Using multiple genetic variants as instrumental variables for modifiable risk factors

Palmer, T. M., Lawlor, D. A., Harbord, R. M., Sheehan, N. A., Tobias, J. H., Timpson, N. J., Davey Smith, G. & Sterne, J. A. C., 06/2012, In: Statistical Methods in Medical Research. 21, 3, p. 223-242 20 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure

Munafò, M. R., Timofeeva, M. N., Morris, R. W., Prieto-Merino, D., Sattar, N., Brennan, P., Johnstone, E. C., Relton, C., Johnson, P. C. D., Walther, D., Whincup, P. H., Casas, J. P., Uhl, G. R., Vineis, P., Padmanabhan, S., Jefferis, B. J., Amuzu, A., Riboli, E., Upton, M. N. & Aveyard, P. & 7 others, Ebrahim, S., Hingorani, A. D., Watt, G., Palmer, T. M., Timpson, N. J., Davey Smith, G. & EPIC Study Group, 16/05/2012, In: JNCI: Journal of the National Cancer Institute. 104, 10, p. 740-748 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach

Nordestgaard, B. G., Palmer, T. M., Benn, M., Zacho, J., Tybjaerg-Hansen, A., Davey Smith, G. & Timpson, N. J., 1/05/2012, In: PLoS Medicine. 9, 5, 13 p., e1001212.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Maternal and offspring adiposity-related genetic variants and gestational weight gain

Lawlor, D. A., Fraser, A., Macdonald-Wallis, C., Nelson, S. M., Palmer, T. M., Davey Smith, G. & Tilling, K., 07/2011, In: American Journal of Clinical Nutrition. 94, 1, p. 149-155 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Smoking is associated with, but does not cause, depressed mood in pregnancy--a mendelian randomization study

Lewis, S. J., Araya, R., Smith, G. D., Freathy, R., Gunnell, D., Palmer, T. & Munafò, M., 07/2011, In: PLoS ONE. 6, 7, 5 p., e21689.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Instrumental variable estimation of causal risk ratios and causal odds ratios in Mendelian randomization analyses

Palmer, T. M., Sterne, J. A. C., Harbord, R. M., Lawlor, D. A., Sheehan, N. A., Meng, S., Granell, R., Smith, G. D. & Didelez, V., 15/06/2011, In: American Journal of Epidemiology. 173, 12, p. 1392-1403 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults

Lawlor, D. A., Harbord, R. M., Tybjaerg-Hansen, A., Palmer, T. M., Zacho, J., Benn, M., Timpson, N. J., Smith, G. D. & Nordestgaard, B. G., 05/2011, In: Journal of Internal Medicine. 269, 5, p. 525-537 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance

De Silva, N. M. G., Freathy, R. M., Palmer, T. M., Donnelly, L. A., Luan, J., Gaunt, T., Langenberg, C., Weedon, M. N., Shields, B., Knight, B. A., Ward, K. J., Sandhu, M. S., Harbord, R. M., McCarthy, M. I., Smith, G. D., Ebrahim, S., Hattersley, A. T., Wareham, N., Lawlor, D. A. & Morris, A. D. & 2 others, Palmer, C. N. A. & Frayling, T. M., 03/2011, In: Diabetes Care. 60, 3, p. 1008-1018 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Nonparametric bounds for the causal effect in a binary instrumental variable model

Palmer, T. M., Ramsahai, R., Didelez, V. & Sheehan, N. A., 2011, In: Stata Journal. 11, 3, p. 345-367 23 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The causal roles of vitamin B(12) and transcobalamin in prostate cancer: can Mendelian randomization analysis provide definitive answers?

Collin, S. M., Metcalfe, C., Palmer, T. M., Refsum, H., Lewis, S. J., Smith, G. D., Cox, A., Davis, M., Marsden, G., Johnston, C., Lane, J. A., Donovan, J. L., Neal, D. E., Hamdy, F. C., Smith, A. D. & Martin, R. M., 2011, In: International Journal of Molecular Epidemiology and Genetics. 2, 4, p. 316-327 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review