Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: genetic variants as instruments for circulating levels

Bonilla, C., Lewis, S. J., Rowlands, M-A., Gaunt, T. R., Smith, G. D., Gunnell, D., Palmer, T., Donovan, J. L., Hamdy, F. C., Neal, D. E., Eeles, R., Easton, D., Kote-Jarai, Z., Olama, A. A. A., Benlloch, S., Muir, K., Giles, G. G., Wiklund, F., Gronberg, H., Haiman, C. A., & 22 othersSchleutker, J., Nordestgaard, B. G., Travis, R. C., Pashayan, N., Khaw, K-T., Stanford, J. L., Blot, W. J., Thibodeau, S., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J., Kaneva, R., Batra, J., Teixeira, M. R., Pandha, H., Lathrop, M., Martin, R. M., Holly, J. M. P. & PRACTICAL consortium, 1/10/2016, In: International Journal of Cancer. 139, 7, p. 1520-1533 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Antipsychotic prescribing in care homes before and after launch of a national dementia strategy: an observational study in English institutions over a 4-year period

Szczepura, A., Wild, D., Khan, A., Owen, D., Palmer, T. M., Muhammad, T., Clark, M. & Bowman, C., 20/09/2016, In: BMJ Open. 6, 9, 11 p., e009882.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk

Tragante, V., Asselbergs, F. W., Swerdlow, D. I., Palmer, T. M., Moore, J. H., Bakker, P. I. W., Keating, B. J. & Holmes, M. V., 05/2016, In: Human Genetics. 135, 5, p. 453-467 15 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

White, J., Sofat, R., Hemani, G., Shah, T., Engmann, J., Dale, C., Shah, S., Kruger, F. A., Giambartolomei, C., Swerdlow, D. I., Palmer, T., McLachlan, S., Langenberg, C., Zabaneh, D., Lovering, R., Cavadino, A., Jefferis, B., Finan, C., Wong, A., Amuzu, A., & 31 othersOng, K., Gaunt, T. R., Warren, H., Davies, T-L., Drenos, F., Cooper, J., Ebrahim, S., Lawlor, D. A., Talmud, P. J., Humphries, S. E., Power, C., Hypponen, E., Richards, M., Hardy, R., Kuh, D., Wareham, N., Ben-Shlomo, Y., Day, I. N., Whincup, P., Morris, R., Strachan, M. W. J., Price, J., Kumari, M., Kivimaki, M., Plagnol, V., Whittaker, J. C., Smith, G. D., Dudbridge, F., Casas, J. P., Holmes, M. V. & Hingorani, A. D., 04/2016, In: The Lancet Diabetes and Endocrinology. 4, 4, p. 327-336 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genetic evidence for causal relationships between maternal obesity-related traits and birth weight

Tyrrell, J., Richmond, R. C. & Palmer, T., 15/03/2016, In: Journal of the American Medical Association. 315, 11, p. 1129-1140 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array

Rodriguez, S., Gaunt, T. R., Guo, Y., Zheng, J., Barnes, M. R., Tang, W., Danish, F., Johnson, A., Castillo, B. A., Li, Y. R., Hakonarson, H., Buxbaum, S. G., Palmer, T., Tsai, M. Y., Lange, L. A., Ebrahim, S., Davey Smith, G., Lawlor, D. A., Folsom, A. R., Hoogeveen, R., & 3 othersReiner, A., Keating, B. & Day, I. N., 01/2016, In: European Journal of Human Genetics. 24, 1, p. 106-112 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Effect of smoking on physical and cognitive capability in later life: a multicohort study using observational and genetic approaches

North, T-L., Palmer, T. M., Lewis, S. J., Cooper, R., Power, C., Pattie, A., Starr, J. M., Deary, I. J., Martin, R. M., Aihie Sayer, A., Kumari, M., Cooper, C., Kivimaki, M., Kuh, D., Ben-Shlomo, Y. & Day, I. N. M., 15/12/2015, In: BMJ Open. 5, 12, 13 p., e008393.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A Mendelian randomization study of circulating uric acid and type 2 diabetes

Sluijs, I., Holmes, M. V., van der Schouw, Y. T., Beulens, J. W. J., Asselbergs, F. W., Huerta, J. M., Palmer, T. M., Arriola, L., Balkau, B., Barricarte, A., Boeing, H., Clavel-Chapelon, F., Fagherazzi, G., Franks, P. W., Gavrila, D., Kaaks, R., Khaw, K. T., Kühn, T., Molina-Montes, E., Mortensen, L. M., & 23 othersNilsson, P. M., Overvad, K., Palli, D., Panico, S., Quirós, J. R., Rolandsson, O., Sacerdote, C., Sala, N., Schmidt, J. A., Scott, R. A., Sieri, S., Slimani, N., Spijkerman, A. M., Tjonneland, A., Travis Dphil, R. C., Tumino, R., van der A, D. L., Sharp, S. J., Forouhi, N. G., Langenberg, C., Riboli, E., Wareham, N. J. & InterAct consortium, 08/2015, In: Diabetes. 64, 8, p. 3028-3036 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Mendelian randomization of blood lipids for coronary heart disease

Holmes, M. V., Asselbergs, F. W., Palmer, T. M., Drenos, F., Lanktree, M. B., Nelson, C. P., Dale, C. E., Padmanabhan, S., Finan, C., Swerdlow, D. I., Tragante, V., van Iperen, E. P. A., Sivapalaratnam, S., Shah, S., Elbers, C. C., Shah, T., Engmann, J., Giambartolomei, C., White, J., Zabaneh, D., & 31 othersSofat, R., McLachlan, S., Doevendans, P. A., Balmforth, A. J., Hall, A. S., North, K. E., Almoguera, B., Hoogeveen, R. C., Cushman, M., Fornage, M., Patel, S. R., Redline, S., Siscovick, D. S., Tsai, M. Y., Karczewski, K. J., Hofker, M. H., Verschuren, W. M., Bots, M. L., van der Schouw, Y. T., Melander, O., Dominiczak, A. F., Morris, R., Ben-Shlomo, Y., Price, J., Kumari, M., Baumert, J., Peters, A., Thorand, B., Koenig, W., Gaunt, T. R. & UCLEB Consortium, 1/03/2015, In: European Heart Journal. 36, 9, p. 539-550 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Systematic review and metaanalysis of genetic association studies of urinary symptoms and prolapse in women

Cartwright, R., Kirby, A. C., Tikkinen, K. A. O., Mangera, A., Thiagamoorthy, G., Rajan, P., Pesonen, J., Ambrose, C., Gonzalez-Maffe, J., Bennett, P., Palmer, T., Walley, A., Järvelin, M-R., Chapple, C. & Khullar, V., 02/2015, In: American Journal of Obstetrics and Gynecology. 212, 2, p. 199.e1-24 24 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Improving health outcomes for young people with long term conditions: The role of digital communication in current and future patient–clinician communication for NHS providers of specialist clinical services for young people – LYNC study protocol

Griffiths, F. E., Atherton, H., Barker, J. R., Cave, J. AK., Dennick, K., Dowdall, P., Fraser, J., Huxley, C., Kim, S-W., Madan, J. J., Matharu, H., Musumadi, L., Palmer, T. M., Paul, M., Sankaranarayanan, S., Slowther, A-M., Sujan, M. A., Sutcliffe, P. A. & Sturt, J., 1/01/2015, In: DIGITAL HEALTH. 1, 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Estimating structural mean models with multiple instrumental variables using the generalised method of moments

Clarke, P., Palmer, T. M. & Windmeijer, F., 2015, In: Statistical Science. 30, 1, p. 96-117 22 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Fitting fixed- and random-effects meta-analysis models using structural equation modeling with the sem and gsem commands

Palmer, T. & Sterne, J. A. C., 2015, In: Stata Journal. 15, 3, p. 645-671 27 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium

Shungin, D., Cornelis, M. C., Divaris, K., Holtfreter, B., Shaffer, J. R., Yu, Y-H., Barros, S. P., Beck, J. D., Biffar, R., Boerwinkle, E. A., Crout, R. J., Ganna, A., Hallmans, G., Hindy, G., Hu, F. B., Kraft, P., McNeil, D. W., Melander, O., Moss, K. L., North, K. E., & 21 othersOrho-Melander, M., Pedersen, N. L., Ridker, P. M., Rimm, E. B., Rose, L. M., Rukh, G., Teumer, A., Weyant, R. J., Chasman, D. I., Joshipura, K., Kocher, T., Magnusson, P. K. E., Marazita, M. L., Nilsson, P., Offenbacher, S., Davey Smith, G., Lundberg, P., Palmer, T. M., Timpson, N. J., Johansson, I. & Franks, P. W., 2015, In: International Journal of Epidemiology. 44, 2, p. 638-650 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits

Silverwood, R. J., Holmes, M. V., Dale, C. E., Lawlor, D. A., Whittaker, J. C., Smith, G. D., Leon, D. A., Palmer, T., Keating, B. J., Zuccolo, L., Casas, J. P., Dudbridge, F. & Alcohol-ADH1B Consortium, 12/2014, In: International Journal of Epidemiology. 43, 6, p. 1781-1790 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Systematic review and meta-analysis of candidate gene association studies of lower urinary tract symptoms in men

Cartwright, R., Mangera, A., Tikkinen, K. A. O., Rajan, P., Pesonen, J., Kirby, A. C., Thiagamoorthy, G., Ambrose, C., Gonzalez-Maffe, J., Bennett, P. R., Palmer, T., Walley, A., Järvelin, M-R., Khullar, V. & Chapple, C., 10/2014, In: European Urology. 66, 4, p. 752-768 17 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Alcohol consumption and cognitive performance: a Mendelian randomization study

Kumari, M., Holmes, M. V., Dale, C. E., Hubacek, J. A., Palmer, T. M., Pikhart, H., Peasey, A., Britton, A., Horvat, P., Kubinova, R., Malyutina, S., Pajak, A., Tamosiunas, A., Shankar, A., Singh-Manoux, A., Voevoda, M., Kivimaki, M., Hingorani, A. D., Marmot, M. G., Casas, J. P., & 1 othersBobak, M., 09/2014, In: Addiction. 109, 9, p. 1462-1471 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

Holmes, M. V., Dale, C. E., Zuccolo, L., Silverwood, R. J., Guo, Y., Ye, Z., Prieto-Merino, D., Dehghan, A., Trompet, S., Wong, A., Cavadino, A., Drogan, D., Padmanabhan, S., Li, S., Yesupriya, A., Leusink, M., Sundstrom, J., Hubacek, J. A., Pikhart, H., Swerdlow, D. I., & 31 othersPanayiotou, A. G., Borinskaya, S. A., Finan, C., Shah, S., Kuchenbaecker, K. B., Shah, T., Engmann, J., Folkersen, L., Eriksson, P., Ricceri, F., Melander, O., Sacerdote, C., Gamble, D. M., Rayaprolu, S., Ross, O. A., McLachlan, S., Vikhireva, O., Sluijs, I., Scott, R. A., Adamkova, V., Flicker, L., Bockxmeer, F. M. V., Power, C., Marques-Vidal, P., Meade, T., Marmot, M. G., Ferro, J. M., Paulos-Pinheiro, S., Humphries, S. E., Palmer, T. M. & InterAct Consortium, 10/07/2014, In: BMJ. 349, 16 p., g4164.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Effects of BMI, fat mass, and lean mass on asthma in childhood: a Mendelian randomization study

Granell, R., Henderson, A. J., Evans, D. M., Smith, G. D., Ness, A. R., Lewis, S., Palmer, T. M. & Sterne, J. A. C., 1/07/2014, In: PLoS Medicine. 11, 7, 14 p., e1001669.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Lack of identification in semiparametric instrumental variable models with binary outcomes

Burgess, S., Granell, R., Palmer, T. M., Sterne, J. A. C. & Didelez, V., 1/07/2014, In: American Journal of Epidemiology. 180, 1, p. 111-119 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genetic variants at chromosome 9p21 and risk of first versus subsequent coronary heart disease events: a systematic review and meta-analysis

Patel, R. S., Asselbergs, F. W., Quyyumi, A. A., Palmer, T. M., Finan, C. I., Tragante, V., Deanfield, J., Hemingway, H., Hingorani, A. D. & Holmes, M. V., 3/06/2014, In: Journal of the American College of Cardiology. 63, 21, p. 2234-2245 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis

Holmes, M. V., Lange, L. A., Palmer, T., Lanktree, M. B., North, K. E., Almoguera, B., Buxbaum, S., Chandrupatla, H. R., Elbers, C. C., Guo, Y., Hoogeveen, R. C., Li, J., Li, Y. R., Swerdlow, D. I., Cushman, M., Price, T. S., Curtis, S. P., Fornage, M., Hakonarson, H., Patel, S. R., & 14 othersRedline, S., Siscovick, D. S., Tsai, M. Y., Wilson, J. G., van der Schouw, Y. T., FitzGerald, G. A., Hingorani, A. D., Casas, J. P., de Bakker, P. I. W., Rich, S. S., Schadt, E. E., Asselbergs, F. W., Reiner, A. P. & Keating, B. J., 6/02/2014, In: American Journal of Human Genetics. 94, 2, p. 198-208 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Effects of promoting longer-term and exclusive breastfeeding on cardiometabolic risk factors at age 11.5 years: a cluster-randomized, controlled trial

Martin, R. M., Patel, R., Kramer, M. S., Vilchuck, K., Bogdanovich, N., Sergeichick, N., Gusina, N., Foo, Y., Palmer, T., Thompson, J., Gillman, M. W., Smith, G. D. & Oken, E., 21/01/2014, In: Circulation. 129, 3, p. 321-329 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Estimating adjusted associations between random effects from multilevel models: the reffadjust package

Palmer, T., Macdonald-Wallis, C., Lawlor, D. & Tilling, K., 2014, In: Stata Journal. 14, 1, p. 119-140 22 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review