A miniaturised isotachophoresis method for magnesium determination

Chemistry

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A miniaturised isotachophoresis method for magnesium determination. / Prest, Jeff E.; Baldock, Sara J.; Fielden, Peter R. et al.
In: Analytical and Bioanalytical Chemistry, Vol. 394, No. 5, 07.2009, p. 1299-1305.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Prest, JE , Baldock, SJ , Fielden, PR, Goddard, NJ & Brown, BJT 2009, 'A miniaturised isotachophoresis method for magnesium determination', Analytical and Bioanalytical Chemistry, vol. 394, no. 5, pp. 1299-1305. https://doi.org/10.1007/s00216-009-2603-5

APA

Prest, J. E., Baldock, S. J., Fielden, P. R., Goddard, N. J., & Brown, B. J. T. (2009). A miniaturised isotachophoresis method for magnesium determination. Analytical and Bioanalytical Chemistry, 394(5), 1299-1305. https://doi.org/10.1007/s00216-009-2603-5

Vancouver

Prest JE , Baldock SJ , Fielden PR, Goddard NJ, Brown BJT. A miniaturised isotachophoresis method for magnesium determination. Analytical and Bioanalytical Chemistry. 2009 Jul;394(5):1299-1305. Epub 2009 Feb 10. doi: 10.1007/s00216-009-2603-5

Author

Prest, Jeff E. ; Baldock, Sara J. ; Fielden, Peter R. et al. / A miniaturised isotachophoresis method for magnesium determination. In: Analytical and Bioanalytical Chemistry. 2009 ; Vol. 394, No. 5. pp. 1299-1305.

Bibtex

@article{71093331093a44fc831a4f3c4d7ebcf3,

title = "A miniaturised isotachophoresis method for magnesium determination",

abstract = "The use of malonic acid as a complexing agent has enabled a new method to be devised to allow the determination of magnesium to be made using miniaturised isotachophoresis. Using a leading electrolyte of 10 mmol L−1 caesium hydroxide and 2 mmol L−1 malonic acid at pH 5.1 gave the method a high specificity towards magnesium. Investigations using a poly(methyl methacrylate) chip device with an integrated conductivity detector showed that no interference from calcium, strontium, barium and sodium should occur. The method was found to be linear over the range of magnesium concentrations from 0.625 to 75 mg L−1 and the limit of detection was calculated to be 0.45 mg L−1. Separations were demonstrated with water samples but the procedure should also be applicable to more complex sample matrices such as inorganic explosive residues, blood or urine.",

keywords = "Isotachophoresis , Miniaturisation, Microdevice, Magnesium , Metal analysis",

author = "Prest, {Jeff E.} and Baldock, {Sara J.} and Fielden, {Peter R.} and Goddard, {Nicholas J.} and Brown, {Bernard J. Treves}",

year = "2009",

month = jul,

doi = "10.1007/s00216-009-2603-5",

language = "English",

volume = "394",

pages = "1299--1305",

journal = "Analytical and Bioanalytical Chemistry",

issn = "1618-2642",

publisher = "Springer Verlag",

number = "5",

}

RIS

TY - JOUR

T1 - A miniaturised isotachophoresis method for magnesium determination

AU - Prest, Jeff E.

AU - Baldock, Sara J.

AU - Fielden, Peter R.

AU - Goddard, Nicholas J.

AU - Brown, Bernard J. Treves

PY - 2009/7

Y1 - 2009/7

N2 - The use of malonic acid as a complexing agent has enabled a new method to be devised to allow the determination of magnesium to be made using miniaturised isotachophoresis. Using a leading electrolyte of 10 mmol L−1 caesium hydroxide and 2 mmol L−1 malonic acid at pH 5.1 gave the method a high specificity towards magnesium. Investigations using a poly(methyl methacrylate) chip device with an integrated conductivity detector showed that no interference from calcium, strontium, barium and sodium should occur. The method was found to be linear over the range of magnesium concentrations from 0.625 to 75 mg L−1 and the limit of detection was calculated to be 0.45 mg L−1. Separations were demonstrated with water samples but the procedure should also be applicable to more complex sample matrices such as inorganic explosive residues, blood or urine.

AB - The use of malonic acid as a complexing agent has enabled a new method to be devised to allow the determination of magnesium to be made using miniaturised isotachophoresis. Using a leading electrolyte of 10 mmol L−1 caesium hydroxide and 2 mmol L−1 malonic acid at pH 5.1 gave the method a high specificity towards magnesium. Investigations using a poly(methyl methacrylate) chip device with an integrated conductivity detector showed that no interference from calcium, strontium, barium and sodium should occur. The method was found to be linear over the range of magnesium concentrations from 0.625 to 75 mg L−1 and the limit of detection was calculated to be 0.45 mg L−1. Separations were demonstrated with water samples but the procedure should also be applicable to more complex sample matrices such as inorganic explosive residues, blood or urine.

KW - Isotachophoresis

KW - Miniaturisation

KW - Microdevice

KW - Magnesium

KW - Metal analysis

U2 - 10.1007/s00216-009-2603-5

DO - 10.1007/s00216-009-2603-5

M3 - Journal article

VL - 394

SP - 1299

EP - 1305

JO - Analytical and Bioanalytical Chemistry

JF - Analytical and Bioanalytical Chemistry

SN - 1618-2642

IS - 5

ER -

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