Adaptation of standard spreadsheet software for the analysis of DNA sequences

Biomedical and Life Sciences

Keywords

Base Sequence, Codon, Molecular Sequence Data, Sequence Analysis, DNA, Software

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Published

Standard

Adaptation of standard spreadsheet software for the analysis of DNA sequences. / McEwan, Neil R.; Gatherer, Derek.
In: Biotechniques, Vol. 24, No. 1, 01.1998, p. 131-136, 138.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Bibtex

@article{27bd21ca469849d8b8b17f5831dc1436,

title = "Adaptation of standard spreadsheet software for the analysis of DNA sequences",

abstract = "This paper presents use of spreadsheet software to derive various statistics on nucleotide and codon distribution and frequency from gene sequence data, including chi 2 test and their derivatives, and proportion of nucleotides in the third position. The basic principles can be easily extended to other more complex functions. In addition, it can be used to translate a nucleic acid sequence into a protein sequence or to produce a codon usage table. This adaptation permits sequence analysis without expensive dedicated software and easy modification of the analysis according to the user's requirements. It is also ideal for introducing biological science students to the programming potential of spreadsheets.",

keywords = "Base Sequence, Codon, Molecular Sequence Data, Sequence Analysis, DNA, Software",

author = "McEwan, {Neil R.} and Derek Gatherer",

year = "1998",

month = jan,

language = "English",

volume = "24",

pages = "131--136, 138",

journal = "Biotechniques",

issn = "0736-6205",

publisher = "Eaton Publishing Company",

number = "1",

}

RIS

TY - JOUR

T1 - Adaptation of standard spreadsheet software for the analysis of DNA sequences

AU - McEwan, Neil R.

AU - Gatherer, Derek

PY - 1998/1

Y1 - 1998/1

N2 - This paper presents use of spreadsheet software to derive various statistics on nucleotide and codon distribution and frequency from gene sequence data, including chi 2 test and their derivatives, and proportion of nucleotides in the third position. The basic principles can be easily extended to other more complex functions. In addition, it can be used to translate a nucleic acid sequence into a protein sequence or to produce a codon usage table. This adaptation permits sequence analysis without expensive dedicated software and easy modification of the analysis according to the user's requirements. It is also ideal for introducing biological science students to the programming potential of spreadsheets.

AB - This paper presents use of spreadsheet software to derive various statistics on nucleotide and codon distribution and frequency from gene sequence data, including chi 2 test and their derivatives, and proportion of nucleotides in the third position. The basic principles can be easily extended to other more complex functions. In addition, it can be used to translate a nucleic acid sequence into a protein sequence or to produce a codon usage table. This adaptation permits sequence analysis without expensive dedicated software and easy modification of the analysis according to the user's requirements. It is also ideal for introducing biological science students to the programming potential of spreadsheets.

KW - Base Sequence

KW - Codon

KW - Molecular Sequence Data

KW - Sequence Analysis, DNA

KW - Software

M3 - Journal article

C2 - 9454965

VL - 24

SP - 131-136, 138

JO - Biotechniques

JF - Biotechniques

SN - 0736-6205

IS - 1

ER -

Research

Keywords