Home > Research > Publications & Outputs > Advanced solid state NMR techniques for the inv...
View graph of relations

Advanced solid state NMR techniques for the investigation of the organic-mineral interfaces in biomaterials: 2009 MRS Fall Meeting

Research output: Contribution to conference - Without ISBN/ISSN Conference paperpeer-review

Published

Standard

Advanced solid state NMR techniques for the investigation of the organic-mineral interfaces in biomaterials: 2009 MRS Fall Meeting. / Laurencin, D.; Guerrero, G.; Amalric, J. et al.
2010. 40-45.

Research output: Contribution to conference - Without ISBN/ISSN Conference paperpeer-review

Harvard

APA

Vancouver

Laurencin D, Guerrero G, Amalric J, Bonhomme C, Gervais C, Smith ME et al.. Advanced solid state NMR techniques for the investigation of the organic-mineral interfaces in biomaterials: 2009 MRS Fall Meeting. 2010. doi: 10.1557/PROC-1236-SS08-02

Author

Bibtex

@conference{f7e6295d7ced4c5fa603a61bad1d829f,
title = "Advanced solid state NMR techniques for the investigation of the organic-mineral interfaces in biomaterials: 2009 MRS Fall Meeting",
abstract = "High resolution solid state NMR experiments were carried out on several compounds, to see how this technique can now be used to investigate in detail the surface structure of different biomaterials. First, because the surface of titanium implants can be functionalized by phosphonic acids, for instance to prevent bacterial adhesion, 17O NMR experiments were performed on model TiO2 surfaces functionalized by 17O enriched phosphonic acids, to look at the mode of grafting of these coupling agents. Results bring clear evidence of the formation of Ti-O-P bridges and of the presence of residual P=O and P-OH groups. Second, given that calcium phosphates are widely present in biological hard tissues and synthetic biomaterials, 43Ca correlation experiments were performed on Ca enriched materials (hydroxyapatite and calcium benzoate), to see how the proximities between this nucleus and neighbouring atoms can be analyzed. Results show that both Ca...C and Ca...H proximities can be evidenced, and could thus help elucidate interface structures. All in all, these studies should pave the way to future investigations of biomaterials, and in particular of the structure of organic-inorganic interfaces. {\textcopyright} 2010 Materials Research Society.",
keywords = "Bacterial adhesion, Calcium benzoate, Functionalized, Hard tissues, High-resolution solid state NMR, Interface structures, OH group, Organic-inorganic interface, Phosphonic acids, Solid state NMR, Synthetic biomaterials, TiO, Titanium implants, Biological materials, Biomaterials, Calcium, Calcium phosphate, Coupling agents, Hydroxyapatite, Light polarization, Nuclear magnetic resonance spectroscopy, Organic acids, Surface structure, Titanium, Experiments",
author = "D. Laurencin and G. Guerrero and J. Amalric and C. Bonhomme and C. Gervais and M.E. Smith and P.H. Mutin",
year = "2010",
doi = "10.1557/PROC-1236-SS08-02",
language = "English",
pages = "40--45",

}

RIS

TY - CONF

T1 - Advanced solid state NMR techniques for the investigation of the organic-mineral interfaces in biomaterials

T2 - 2009 MRS Fall Meeting

AU - Laurencin, D.

AU - Guerrero, G.

AU - Amalric, J.

AU - Bonhomme, C.

AU - Gervais, C.

AU - Smith, M.E.

AU - Mutin, P.H.

PY - 2010

Y1 - 2010

N2 - High resolution solid state NMR experiments were carried out on several compounds, to see how this technique can now be used to investigate in detail the surface structure of different biomaterials. First, because the surface of titanium implants can be functionalized by phosphonic acids, for instance to prevent bacterial adhesion, 17O NMR experiments were performed on model TiO2 surfaces functionalized by 17O enriched phosphonic acids, to look at the mode of grafting of these coupling agents. Results bring clear evidence of the formation of Ti-O-P bridges and of the presence of residual P=O and P-OH groups. Second, given that calcium phosphates are widely present in biological hard tissues and synthetic biomaterials, 43Ca correlation experiments were performed on Ca enriched materials (hydroxyapatite and calcium benzoate), to see how the proximities between this nucleus and neighbouring atoms can be analyzed. Results show that both Ca...C and Ca...H proximities can be evidenced, and could thus help elucidate interface structures. All in all, these studies should pave the way to future investigations of biomaterials, and in particular of the structure of organic-inorganic interfaces. © 2010 Materials Research Society.

AB - High resolution solid state NMR experiments were carried out on several compounds, to see how this technique can now be used to investigate in detail the surface structure of different biomaterials. First, because the surface of titanium implants can be functionalized by phosphonic acids, for instance to prevent bacterial adhesion, 17O NMR experiments were performed on model TiO2 surfaces functionalized by 17O enriched phosphonic acids, to look at the mode of grafting of these coupling agents. Results bring clear evidence of the formation of Ti-O-P bridges and of the presence of residual P=O and P-OH groups. Second, given that calcium phosphates are widely present in biological hard tissues and synthetic biomaterials, 43Ca correlation experiments were performed on Ca enriched materials (hydroxyapatite and calcium benzoate), to see how the proximities between this nucleus and neighbouring atoms can be analyzed. Results show that both Ca...C and Ca...H proximities can be evidenced, and could thus help elucidate interface structures. All in all, these studies should pave the way to future investigations of biomaterials, and in particular of the structure of organic-inorganic interfaces. © 2010 Materials Research Society.

KW - Bacterial adhesion

KW - Calcium benzoate

KW - Functionalized

KW - Hard tissues

KW - High-resolution solid state NMR

KW - Interface structures

KW - OH group

KW - Organic-inorganic interface

KW - Phosphonic acids

KW - Solid state NMR

KW - Synthetic biomaterials

KW - TiO

KW - Titanium implants

KW - Biological materials

KW - Biomaterials

KW - Calcium

KW - Calcium phosphate

KW - Coupling agents

KW - Hydroxyapatite

KW - Light polarization

KW - Nuclear magnetic resonance spectroscopy

KW - Organic acids

KW - Surface structure

KW - Titanium

KW - Experiments

U2 - 10.1557/PROC-1236-SS08-02

DO - 10.1557/PROC-1236-SS08-02

M3 - Conference paper

SP - 40

EP - 45

ER -