Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Advances of proteomic sciences in dentistry
AU - Khurshid, Z.
AU - Zohaib, S.
AU - Najeeb, S.
AU - Zafar, M.S.
AU - Rehman, R.
AU - Ur Rehman, I.
PY - 2016/5/13
Y1 - 2016/5/13
N2 - Applications of proteomics tools revolutionized various biomedical disciplines such as genetics, molecular biology, medicine, and dentistry. The aim of this review is to highlight the major milestones in proteomics in dentistry during the last fifteen years. Human oral cavity contains hard and soft tissues and various biofluids including saliva and crevicular fluid. Proteomics has brought revolution in dentistry by helping in the early diagnosis of various diseases identified by the detection of numerous biomarkers present in the oral fluids. This paper covers the role of proteomics tools for the analysis of oral tissues. In addition, dental materials proteomics and their future directions are discussed. © 2016 by the authors; licensee MDPI, Basel, Switzerland.
AB - Applications of proteomics tools revolutionized various biomedical disciplines such as genetics, molecular biology, medicine, and dentistry. The aim of this review is to highlight the major milestones in proteomics in dentistry during the last fifteen years. Human oral cavity contains hard and soft tissues and various biofluids including saliva and crevicular fluid. Proteomics has brought revolution in dentistry by helping in the early diagnosis of various diseases identified by the detection of numerous biomarkers present in the oral fluids. This paper covers the role of proteomics tools for the analysis of oral tissues. In addition, dental materials proteomics and their future directions are discussed. © 2016 by the authors; licensee MDPI, Basel, Switzerland.
KW - Dentin
KW - Dentistry
KW - Enamel
KW - Gingival crevicular fluids and dental materials
KW - Proteomics
KW - Saliva
KW - ameloblastin
KW - amelogenin
KW - matrix metalloproteinase
KW - dental material
KW - proteome
KW - chronic periodontitis
KW - dentistry
KW - enzyme linked immunosorbent assay
KW - extracellular matrix
KW - gingivitis
KW - human
KW - immune response
KW - liquid chromatography
KW - microarray analysis
KW - mouth cavity
KW - protein binding
KW - protein expression
KW - proteomics
KW - real time polymerase chain reaction
KW - Review
KW - surface enhanced laser desorption ionization time of flight mass spectrometry
KW - two dimensional electrophoresis
KW - Western blotting
KW - drug effects
KW - genetics
KW - metabolism
KW - periodontium
KW - procedures
KW - standards
KW - tooth
KW - Dental Materials
KW - Humans
KW - Periodontium
KW - Proteome
KW - Tooth
U2 - 10.3390/ijms17050728
DO - 10.3390/ijms17050728
M3 - Journal article
VL - 17
JO - International Journal of Molecular Sciences
JF - International Journal of Molecular Sciences
SN - 1661-6596
IS - 5
M1 - 728
ER -