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Adverse obstetric outcomes after local treatment for cervical preinvasive and early invasive disease according to cone depth: systematic review and meta-analysis

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  • Maria Kyrgiou
  • Antonios Athanasiou
  • Maria Paraskevaidi
  • Anita Mitra
  • Ilkka Kalliala
  • Pierre Leonard Martin-Hirsch
  • Marc Arbyn
  • Phillip Bennett
  • Evangelos Paraskevaidis
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<mark>Journal publication date</mark>1/11/2016
<mark>Journal</mark>Obstetrical and Gynecological Survey
Issue number11
Volume71
Number of pages3
Pages (from-to)646-648
Publication StatusPublished
<mark>Original language</mark>English

Abstract

Local cervical treatment for preinvasive cervical disease such as cervical intraepithelial neoplasia (CIN) has been associated with an increased risk of preterm birth, perinatal morbidity, and mortality in a later pregnancy. This meta-analysis aimed to investigate the impact of treatment for cervical preinvasive and early invasive disease on obstetric outcomes and to see how this risk could be modified by the cone depth and comparison group.