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An application of ionic liquid for preparation of homogeneous collagen and alginate hydrogels for skin dressing

Research output: Contribution to Journal/MagazineJournal articlepeer-review

  • Bushra Iqbal
  • Nawshad Muhammad
  • Arshad Jamal
  • Pervaiz Ahmad
  • Zia Ul Haq Khan
  • Abdur Rahim
  • Amir Sada Khan
  • Girma Gonfa
  • Jibran Iqbal
  • Ihtesham Ur Rehman
<mark>Journal publication date</mark>1/10/2017
<mark>Journal</mark>Journal of Molecular Liquids
Number of pages6
Pages (from-to)720-725
Publication StatusPublished
Early online date30/08/17
<mark>Original language</mark>English


Ionic liquid due to its green nature as well as having the ability to dissolve biopolymer, was used in the preparation of collagen and alginate hydrogels. The collagen and alginate hydrogels were prepared in different ratios of collagen and alginate, labeled CA5040, CA6030 and CA7020. The prepared hydrogels were characterized with Fourier-transform infrared spectroscopy (FTIR), Scanning electron microscope (SEM), Thermogravimetric analysis (TGA) analysis. The samples were evaluated for water uptake behavior and mechanical properties using electrodynamic fatigue testing system. The biocompatibility was assessed through hemolysis and MTT assay on rat mesenchymal stem cells (rMSC) which showed satisfactory results. The drug loading and subsequent antibacterial properties were also performed. The prepared collagen and alginate hydrogels are suggested to be used for skin dressing.