Final published version
Research output: Contribution to Journal/Magazine › Review article › peer-review
Research output: Contribution to Journal/Magazine › Review article › peer-review
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TY - JOUR
T1 - An Overview of Aptamer-Based Sensor Platforms for the Detection of Bisphenol-A
AU - Caglayan, Mustafa Oguzhan
AU - Şahin, Samet
AU - Üstündağ, Zafer
PY - 2022/8/24
Y1 - 2022/8/24
N2 - Endocrine disruptive compounds are natural or anthropogenic environmental micropollutants that alter the function of the endocrine system ultimately damaging the metabolism. Bisphenol A (BPA) is the most common of these pollutants and it is often used in epoxy coatings and polycarbonates as a plasticizer. Therefore, monitoring BPA levels in different environments is very important and challenging. In recent years, an increasing number of BPA detection methods have been proposed. This article presents a critical review of aptamer-based electrochemical, fluorescence-based, colorimetric, and several other BPA detection platforms published in the last decade. Furthermore, a statistical evaluation has been made using principle component analysis showing analytical performance parameters do not create very different clusters. Comparisons to other BPA detection methods are also presented so that the reader has an overall literature overview.
AB - Endocrine disruptive compounds are natural or anthropogenic environmental micropollutants that alter the function of the endocrine system ultimately damaging the metabolism. Bisphenol A (BPA) is the most common of these pollutants and it is often used in epoxy coatings and polycarbonates as a plasticizer. Therefore, monitoring BPA levels in different environments is very important and challenging. In recent years, an increasing number of BPA detection methods have been proposed. This article presents a critical review of aptamer-based electrochemical, fluorescence-based, colorimetric, and several other BPA detection platforms published in the last decade. Furthermore, a statistical evaluation has been made using principle component analysis showing analytical performance parameters do not create very different clusters. Comparisons to other BPA detection methods are also presented so that the reader has an overall literature overview.
KW - aptamers
KW - biosensor
KW - Bisphenol A
KW - endocrine disruptive compounds
U2 - 10.1080/10408347.2022.2113359
DO - 10.1080/10408347.2022.2113359
M3 - Review article
AN - SCOPUS:85136548585
JO - Critical Reviews in Analytical Chemistry
JF - Critical Reviews in Analytical Chemistry
SN - 1040-8347
ER -