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Assessment of the Oral Bioavailability of Organic Contaminants in Humans

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Assessment of the Oral Bioavailability of Organic Contaminants in Humans. / Wijayawardena, M.A.A.; Liu, Y.; Yan, K.; Duan, L.; Umeh, A.C.; Naidu, R.; Semple, K.T.

Bioavailability of Organic Chemicals in Soil and Sediment . ed. / Jose Julio Ortega-Calvo; John Robert Parsons. Cham : Springer, 2020. p. 191-218 (Handbook of Environmental Chemistry; Vol. 100).

Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter (peer-reviewed)peer-review

Harvard

Wijayawardena, MAA, Liu, Y, Yan, K, Duan, L, Umeh, AC, Naidu, R & Semple, KT 2020, Assessment of the Oral Bioavailability of Organic Contaminants in Humans. in JJ Ortega-Calvo & JR Parsons (eds), Bioavailability of Organic Chemicals in Soil and Sediment . Handbook of Environmental Chemistry, vol. 100, Springer, Cham, pp. 191-218. https://doi.org/10.1007/698_2020_596

APA

Wijayawardena, M. A. A., Liu, Y., Yan, K., Duan, L., Umeh, A. C., Naidu, R., & Semple, K. T. (2020). Assessment of the Oral Bioavailability of Organic Contaminants in Humans. In J. J. Ortega-Calvo, & J. R. Parsons (Eds.), Bioavailability of Organic Chemicals in Soil and Sediment (pp. 191-218). (Handbook of Environmental Chemistry; Vol. 100). Springer. https://doi.org/10.1007/698_2020_596

Vancouver

Wijayawardena MAA, Liu Y, Yan K, Duan L, Umeh AC, Naidu R et al. Assessment of the Oral Bioavailability of Organic Contaminants in Humans. In Ortega-Calvo JJ, Parsons JR, editors, Bioavailability of Organic Chemicals in Soil and Sediment . Cham: Springer. 2020. p. 191-218. (Handbook of Environmental Chemistry). https://doi.org/10.1007/698_2020_596

Author

Wijayawardena, M.A.A. ; Liu, Y. ; Yan, K. ; Duan, L. ; Umeh, A.C. ; Naidu, R. ; Semple, K.T. / Assessment of the Oral Bioavailability of Organic Contaminants in Humans. Bioavailability of Organic Chemicals in Soil and Sediment . editor / Jose Julio Ortega-Calvo ; John Robert Parsons. Cham : Springer, 2020. pp. 191-218 (Handbook of Environmental Chemistry).

Bibtex

@inbook{d40510ccd29743c3b14f5f2770015718,
title = "Assessment of the Oral Bioavailability of Organic Contaminants in Humans",
abstract = "Bioavailability estimates the actual internal uptake or absorption of contaminants that enter the body (internal dose) and helps in providing a more accurate estimation of the human risks than the usage of total concentration. This is important for exposure assessment for children in relation to their hand-to-mouth activities. For example significant reductions of the bioavailability of long-term contaminated soils have been demonstrated using various animal models. The measurement for bioavailability involves various uncertainties for organic contaminants. It is crucial to determine the parameters that influence the results of bioavailability. This chapter provides a summary of the current state of knowledge for the determination of bioavailability for a range of organic contaminants. The information provided will be useful in facilitating further research efforts for the investigation of bioavailability of contaminants in conducting exposure assessments. ",
keywords = "Bioaccumulation, Bioavailability, Diffusion, Dissolution, Electrophilic, Perfusion rate, Permeability rate",
author = "M.A.A. Wijayawardena and Y. Liu and K. Yan and L. Duan and A.C. Umeh and R. Naidu and K.T. Semple",
year = "2020",
month = jul,
day = "9",
doi = "10.1007/698_2020_596",
language = "English",
isbn = "9783030579180",
series = "Handbook of Environmental Chemistry",
publisher = "Springer",
pages = "191--218",
editor = "Ortega-Calvo, {Jose Julio} and Parsons, {John Robert}",
booktitle = "Bioavailability of Organic Chemicals in Soil and Sediment",

}

RIS

TY - CHAP

T1 - Assessment of the Oral Bioavailability of Organic Contaminants in Humans

AU - Wijayawardena, M.A.A.

AU - Liu, Y.

AU - Yan, K.

AU - Duan, L.

AU - Umeh, A.C.

AU - Naidu, R.

AU - Semple, K.T.

PY - 2020/7/9

Y1 - 2020/7/9

N2 - Bioavailability estimates the actual internal uptake or absorption of contaminants that enter the body (internal dose) and helps in providing a more accurate estimation of the human risks than the usage of total concentration. This is important for exposure assessment for children in relation to their hand-to-mouth activities. For example significant reductions of the bioavailability of long-term contaminated soils have been demonstrated using various animal models. The measurement for bioavailability involves various uncertainties for organic contaminants. It is crucial to determine the parameters that influence the results of bioavailability. This chapter provides a summary of the current state of knowledge for the determination of bioavailability for a range of organic contaminants. The information provided will be useful in facilitating further research efforts for the investigation of bioavailability of contaminants in conducting exposure assessments.

AB - Bioavailability estimates the actual internal uptake or absorption of contaminants that enter the body (internal dose) and helps in providing a more accurate estimation of the human risks than the usage of total concentration. This is important for exposure assessment for children in relation to their hand-to-mouth activities. For example significant reductions of the bioavailability of long-term contaminated soils have been demonstrated using various animal models. The measurement for bioavailability involves various uncertainties for organic contaminants. It is crucial to determine the parameters that influence the results of bioavailability. This chapter provides a summary of the current state of knowledge for the determination of bioavailability for a range of organic contaminants. The information provided will be useful in facilitating further research efforts for the investigation of bioavailability of contaminants in conducting exposure assessments.

KW - Bioaccumulation

KW - Bioavailability

KW - Diffusion

KW - Dissolution

KW - Electrophilic

KW - Perfusion rate

KW - Permeability rate

U2 - 10.1007/698_2020_596

DO - 10.1007/698_2020_596

M3 - Chapter (peer-reviewed)

SN - 9783030579180

T3 - Handbook of Environmental Chemistry

SP - 191

EP - 218

BT - Bioavailability of Organic Chemicals in Soil and Sediment

A2 - Ortega-Calvo, Jose Julio

A2 - Parsons, John Robert

PB - Springer

CY - Cham

ER -