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Associations between childhood maltreatment and inflammatory markers.

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Associations between childhood maltreatment and inflammatory markers. / Palmos, AB; Watson, S; Hughes, T et al.
In: BJPsych Open, Vol. 5, No. 1, e3, 31.01.2019.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Harvard

Palmos, AB, Watson, S, Hughes, T, Finkelmeyer, A, McAllister-Williams, RH, Ferrier, N, Anderson, IM, Nair, R, Young, AH, Strawbridge, R, Cleare, AJ, Chung, R, Frissa, S, Goodwin, L, Hotopf, M, Hatch, SL, Wang, H, Collier, DA, Thuret, S, Breen, G & Powell, TR 2019, 'Associations between childhood maltreatment and inflammatory markers.', BJPsych Open, vol. 5, no. 1, e3. https://doi.org/10.1192/bjo.2018.80

APA

Palmos, AB., Watson, S., Hughes, T., Finkelmeyer, A., McAllister-Williams, RH., Ferrier, N., Anderson, IM., Nair, R., Young, AH., Strawbridge, R., Cleare, AJ., Chung, R., Frissa, S., Goodwin, L., Hotopf, M., Hatch, S. L., Wang, H., Collier, D. A., Thuret, S., ... Powell, T. R. (2019). Associations between childhood maltreatment and inflammatory markers. BJPsych Open, 5(1), Article e3. https://doi.org/10.1192/bjo.2018.80

Vancouver

Palmos AB, Watson S, Hughes T, Finkelmeyer A, McAllister-Williams RH, Ferrier N et al. Associations between childhood maltreatment and inflammatory markers. BJPsych Open. 2019 Jan 31;5(1):e3. Epub 2019 Jan 4. doi: 10.1192/bjo.2018.80

Author

Palmos, AB ; Watson, S ; Hughes, T et al. / Associations between childhood maltreatment and inflammatory markers. In: BJPsych Open. 2019 ; Vol. 5, No. 1.

Bibtex

@article{b897050ef16a4cc1a53c62e5d44f896d,
title = "Associations between childhood maltreatment and inflammatory markers.",
abstract = "BackgroundChildhood maltreatment is one of the strongest predictors of adulthood depression and alterations to circulating levels of inflammatory markers is one putative mechanism mediating risk or resilience.AimsTo determine the effects of childhood maltreatment on circulating levels of 41 inflammatory markers in healthy individuals and those with a major depressive disorder (MDD) diagnosis.MethodWe investigated the association of childhood maltreatment with levels of 41 inflammatory markers in two groups, 164 patients with MDD and 301 controls, using multiplex electrochemiluminescence methods applied to blood serum.ResultsChildhood maltreatment was not associated with altered inflammatory markers in either group after multiple testing correction. Body mass index (BMI) exerted strong effects on interleukin-6 and C-reactive protein levels in those with MDD.ConclusionsChildhood maltreatment did not exert effects on inflammatory marker levels in either the participants with MDD or the control group in our study. Our results instead highlight the more pertinent influence of BMI.",
author = "AB Palmos and S Watson and T Hughes and A Finkelmeyer and RH McAllister-Williams and N Ferrier and IM Anderson and R Nair and AH Young and R Strawbridge and AJ Cleare and R Chung and S Frissa and Laura Goodwin and Matthew Hotopf and Hatch, {Stephani L.} and Hong Wang and Collier, {David A} and Sandrine Thuret and Gerome Breen and Powell, {Timothy R}",
year = "2019",
month = jan,
day = "31",
doi = "10.1192/bjo.2018.80",
language = "English",
volume = "5",
journal = "BJPsych Open",
issn = "2056-4724",
publisher = "Cambridge University Press",
number = "1",

}

RIS

TY - JOUR

T1 - Associations between childhood maltreatment and inflammatory markers.

AU - Palmos, AB

AU - Watson, S

AU - Hughes, T

AU - Finkelmeyer, A

AU - McAllister-Williams, RH

AU - Ferrier, N

AU - Anderson, IM

AU - Nair, R

AU - Young, AH

AU - Strawbridge, R

AU - Cleare, AJ

AU - Chung, R

AU - Frissa, S

AU - Goodwin, Laura

AU - Hotopf, Matthew

AU - Hatch, Stephani L.

AU - Wang, Hong

AU - Collier, David A

AU - Thuret, Sandrine

AU - Breen, Gerome

AU - Powell, Timothy R

PY - 2019/1/31

Y1 - 2019/1/31

N2 - BackgroundChildhood maltreatment is one of the strongest predictors of adulthood depression and alterations to circulating levels of inflammatory markers is one putative mechanism mediating risk or resilience.AimsTo determine the effects of childhood maltreatment on circulating levels of 41 inflammatory markers in healthy individuals and those with a major depressive disorder (MDD) diagnosis.MethodWe investigated the association of childhood maltreatment with levels of 41 inflammatory markers in two groups, 164 patients with MDD and 301 controls, using multiplex electrochemiluminescence methods applied to blood serum.ResultsChildhood maltreatment was not associated with altered inflammatory markers in either group after multiple testing correction. Body mass index (BMI) exerted strong effects on interleukin-6 and C-reactive protein levels in those with MDD.ConclusionsChildhood maltreatment did not exert effects on inflammatory marker levels in either the participants with MDD or the control group in our study. Our results instead highlight the more pertinent influence of BMI.

AB - BackgroundChildhood maltreatment is one of the strongest predictors of adulthood depression and alterations to circulating levels of inflammatory markers is one putative mechanism mediating risk or resilience.AimsTo determine the effects of childhood maltreatment on circulating levels of 41 inflammatory markers in healthy individuals and those with a major depressive disorder (MDD) diagnosis.MethodWe investigated the association of childhood maltreatment with levels of 41 inflammatory markers in two groups, 164 patients with MDD and 301 controls, using multiplex electrochemiluminescence methods applied to blood serum.ResultsChildhood maltreatment was not associated with altered inflammatory markers in either group after multiple testing correction. Body mass index (BMI) exerted strong effects on interleukin-6 and C-reactive protein levels in those with MDD.ConclusionsChildhood maltreatment did not exert effects on inflammatory marker levels in either the participants with MDD or the control group in our study. Our results instead highlight the more pertinent influence of BMI.

U2 - 10.1192/bjo.2018.80

DO - 10.1192/bjo.2018.80

M3 - Journal article

C2 - 30762500

VL - 5

JO - BJPsych Open

JF - BJPsych Open

SN - 2056-4724

IS - 1

M1 - e3

ER -