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Attraction of Lutzomyia longipalpis to synthetic sex-aggregation pheromone: Effect of release rate and proximity of adjacent pheromone sources

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Attraction of Lutzomyia longipalpis to synthetic sex-aggregation pheromone : Effect of release rate and proximity of adjacent pheromone sources. / Bell, Melissa J.; Sedda, Luigi; Gonzalez, Mikel A.; de Souza, Cristian F.; Dilger, Erin; Brazil, Reginaldo P.; Courtenay, Orin; Hamilton, James G. C.

In: PLoS Neglected Tropical Diseases, Vol. 12, No. 12, e0007007, 19.12.2018.

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Bell, Melissa J. ; Sedda, Luigi ; Gonzalez, Mikel A. ; de Souza, Cristian F. ; Dilger, Erin ; Brazil, Reginaldo P. ; Courtenay, Orin ; Hamilton, James G. C. / Attraction of Lutzomyia longipalpis to synthetic sex-aggregation pheromone : Effect of release rate and proximity of adjacent pheromone sources. In: PLoS Neglected Tropical Diseases. 2018 ; Vol. 12, No. 12.

Bibtex

@article{e9b6d89b98c24440a55f514097cc15ff,
title = "Attraction of Lutzomyia longipalpis to synthetic sex-aggregation pheromone: Effect of release rate and proximity of adjacent pheromone sources",
abstract = "In South America, the Protist parasite that causes visceral leishmaniasis, a potentially fatal human disease, is transmitted by blood-feeding female Lutzomyia longipalpis sand flies. A synthetic copy of the male produced sex-aggregation pheromone offers new opportunities for vector control applications. We have previously shown that the pheromone placed in plastic sachets (lures) can attract both females and males to insecticide treated sites for up to 3 months. To use the pheromone lure in a control program we need to understand how the application of lures in the field can be optimised. In this study we investigated the effect of increasing the number of lures and their proximity to each other on their ability to attract Lu. longipalpis. Also for the first time we applied a Bayesian log-linear model rather than a classic simple (deterministic) log-linear model to fully exploit the field-collected data. We found that sand fly response to pheromone is significantly related to the quantity of pheromone and is not influenced by the proximity of other pheromone sources. Thus sand flies are attracted to the pheromone source at a non-linear rate determined by the amount of pheromone being released. This rate is independent of the proximity of other pheromone releasing traps and indicates the role of the pheromone in aggregation formation. These results have important implications for optimisation of the pheromone as a vector control tool and indicate that multiple lures placed in relatively close proximity to each other (5 m apart) are unlikely to interfere with one another.",
keywords = "PHLEBOTOMINE SAND FLIES, VISCERAL LEISHMANIASIS, MINAS-GERAIS, RIO-DOCE, PSYCHODIDAE, DIPTERA, STATE, KAIROMONES, INFECTION, TRAPS",
author = "Bell, {Melissa J.} and Luigi Sedda and Gonzalez, {Mikel A.} and {de Souza}, {Cristian F.} and Erin Dilger and Brazil, {Reginaldo P.} and Orin Courtenay and Hamilton, {James G. C.}",
year = "2018",
month = dec,
day = "19",
doi = "10.1371/journal.pntd.0007007",
language = "English",
volume = "12",
journal = "PLoS Neglected Tropical Diseases",
issn = "1935-2727",
publisher = "Public Library of Science",
number = "12",

}

RIS

TY - JOUR

T1 - Attraction of Lutzomyia longipalpis to synthetic sex-aggregation pheromone

T2 - Effect of release rate and proximity of adjacent pheromone sources

AU - Bell, Melissa J.

AU - Sedda, Luigi

AU - Gonzalez, Mikel A.

AU - de Souza, Cristian F.

AU - Dilger, Erin

AU - Brazil, Reginaldo P.

AU - Courtenay, Orin

AU - Hamilton, James G. C.

PY - 2018/12/19

Y1 - 2018/12/19

N2 - In South America, the Protist parasite that causes visceral leishmaniasis, a potentially fatal human disease, is transmitted by blood-feeding female Lutzomyia longipalpis sand flies. A synthetic copy of the male produced sex-aggregation pheromone offers new opportunities for vector control applications. We have previously shown that the pheromone placed in plastic sachets (lures) can attract both females and males to insecticide treated sites for up to 3 months. To use the pheromone lure in a control program we need to understand how the application of lures in the field can be optimised. In this study we investigated the effect of increasing the number of lures and their proximity to each other on their ability to attract Lu. longipalpis. Also for the first time we applied a Bayesian log-linear model rather than a classic simple (deterministic) log-linear model to fully exploit the field-collected data. We found that sand fly response to pheromone is significantly related to the quantity of pheromone and is not influenced by the proximity of other pheromone sources. Thus sand flies are attracted to the pheromone source at a non-linear rate determined by the amount of pheromone being released. This rate is independent of the proximity of other pheromone releasing traps and indicates the role of the pheromone in aggregation formation. These results have important implications for optimisation of the pheromone as a vector control tool and indicate that multiple lures placed in relatively close proximity to each other (5 m apart) are unlikely to interfere with one another.

AB - In South America, the Protist parasite that causes visceral leishmaniasis, a potentially fatal human disease, is transmitted by blood-feeding female Lutzomyia longipalpis sand flies. A synthetic copy of the male produced sex-aggregation pheromone offers new opportunities for vector control applications. We have previously shown that the pheromone placed in plastic sachets (lures) can attract both females and males to insecticide treated sites for up to 3 months. To use the pheromone lure in a control program we need to understand how the application of lures in the field can be optimised. In this study we investigated the effect of increasing the number of lures and their proximity to each other on their ability to attract Lu. longipalpis. Also for the first time we applied a Bayesian log-linear model rather than a classic simple (deterministic) log-linear model to fully exploit the field-collected data. We found that sand fly response to pheromone is significantly related to the quantity of pheromone and is not influenced by the proximity of other pheromone sources. Thus sand flies are attracted to the pheromone source at a non-linear rate determined by the amount of pheromone being released. This rate is independent of the proximity of other pheromone releasing traps and indicates the role of the pheromone in aggregation formation. These results have important implications for optimisation of the pheromone as a vector control tool and indicate that multiple lures placed in relatively close proximity to each other (5 m apart) are unlikely to interfere with one another.

KW - PHLEBOTOMINE SAND FLIES

KW - VISCERAL LEISHMANIASIS

KW - MINAS-GERAIS

KW - RIO-DOCE

KW - PSYCHODIDAE

KW - DIPTERA

KW - STATE

KW - KAIROMONES

KW - INFECTION

KW - TRAPS

U2 - 10.1371/journal.pntd.0007007

DO - 10.1371/journal.pntd.0007007

M3 - Journal article

VL - 12

JO - PLoS Neglected Tropical Diseases

JF - PLoS Neglected Tropical Diseases

SN - 1935-2727

IS - 12

M1 - e0007007

ER -