Auditory brainstem correlates of basilar membrane nonlinearity in humans

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Auditory brainstem correlates of basilar membrane nonlinearity in humans. / Krishnan, Ananthanarayan; Plack, Christopher J.
In: Audiology and Neurotology, Vol. 14, No. 2, 2009, p. 88-97.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Krishnan, Ananthanarayan ; Plack, Christopher J. / Auditory brainstem correlates of basilar membrane nonlinearity in humans. In: Audiology and Neurotology. 2009 ; Vol. 14, No. 2. pp. 88-97.

Bibtex

@article{083deab6d58c4762a96acf82c01a681e,

title = "Auditory brainstem correlates of basilar membrane nonlinearity in humans",

abstract = "A behavioral measure of the basilar membrane response can be obtained by comparing the growth in forward masking for maskers at, and well below, the signal frequency. Since the off-frequency masker is assumed to be processed linearly at the signal place, the difference in masking growth with level is thought to reflect the compressive response to the on-frequency masker. The present experiment used an electrophysiological analog of this technique, based on measurements of the latency of wave V of the auditory brain-stem response elicited by a 4-kHz, 4-ms pure tone, presented at 65 dB SPL. Responses were obtained in quiet and in the presence of either an on-frequency (4 kHz) or an off-frequency (1.8 kHz) pure-tone forward masker. Wave V latency increased with masker level, although the increase was greater for the off-frequency masker than for the on-frequency masker, consistent with a more compressive response to the latter. Response functions generated from the data showed the characteristic shape, with a nearly linear response at lower levels and 4: 1 compression at higher levels. However, the breakpoint between the linear region and the compressive region was at about 60 dB SPL, higher than expected on the basis of previous physiological and psychophysical measures. ",

keywords = "On-frequency, Off-frequency, Latency shift, Linear, Compressive nonlinearity, Basilar membrane input-output function, CROSSED OLIVOCOCHLEAR BUNDLE, MIDDLE LATENCY RESPONSES, FORWARD-MASKING PARADIGM, INPUT-OUTPUT FUNCTIONS, WHOLE-NERVE AP, GUINEA-PIG, FREQUENCY SPECIFICITY, CHINCHILLA COCHLEA, EVOKED-POTENTIALS, NORMAL-HEARING",

author = "Ananthanarayan Krishnan and Plack, {Christopher J.}",

year = "2009",

doi = "10.1159/000158537",

language = "English",

volume = "14",

pages = "88--97",

journal = "Audiology and Neurotology",

issn = "1420-3030",

publisher = "S. Karger AG",

number = "2",

}

RIS

TY - JOUR

T1 - Auditory brainstem correlates of basilar membrane nonlinearity in humans

AU - Krishnan, Ananthanarayan

AU - Plack, Christopher J.

PY - 2009

Y1 - 2009

N2 - A behavioral measure of the basilar membrane response can be obtained by comparing the growth in forward masking for maskers at, and well below, the signal frequency. Since the off-frequency masker is assumed to be processed linearly at the signal place, the difference in masking growth with level is thought to reflect the compressive response to the on-frequency masker. The present experiment used an electrophysiological analog of this technique, based on measurements of the latency of wave V of the auditory brain-stem response elicited by a 4-kHz, 4-ms pure tone, presented at 65 dB SPL. Responses were obtained in quiet and in the presence of either an on-frequency (4 kHz) or an off-frequency (1.8 kHz) pure-tone forward masker. Wave V latency increased with masker level, although the increase was greater for the off-frequency masker than for the on-frequency masker, consistent with a more compressive response to the latter. Response functions generated from the data showed the characteristic shape, with a nearly linear response at lower levels and 4: 1 compression at higher levels. However, the breakpoint between the linear region and the compressive region was at about 60 dB SPL, higher than expected on the basis of previous physiological and psychophysical measures.

AB - A behavioral measure of the basilar membrane response can be obtained by comparing the growth in forward masking for maskers at, and well below, the signal frequency. Since the off-frequency masker is assumed to be processed linearly at the signal place, the difference in masking growth with level is thought to reflect the compressive response to the on-frequency masker. The present experiment used an electrophysiological analog of this technique, based on measurements of the latency of wave V of the auditory brain-stem response elicited by a 4-kHz, 4-ms pure tone, presented at 65 dB SPL. Responses were obtained in quiet and in the presence of either an on-frequency (4 kHz) or an off-frequency (1.8 kHz) pure-tone forward masker. Wave V latency increased with masker level, although the increase was greater for the off-frequency masker than for the on-frequency masker, consistent with a more compressive response to the latter. Response functions generated from the data showed the characteristic shape, with a nearly linear response at lower levels and 4: 1 compression at higher levels. However, the breakpoint between the linear region and the compressive region was at about 60 dB SPL, higher than expected on the basis of previous physiological and psychophysical measures.

KW - On-frequency

KW - Off-frequency

KW - Latency shift

KW - Linear

KW - Compressive nonlinearity

KW - Basilar membrane input-output function

KW - CROSSED OLIVOCOCHLEAR BUNDLE

KW - MIDDLE LATENCY RESPONSES

KW - FORWARD-MASKING PARADIGM

KW - INPUT-OUTPUT FUNCTIONS

KW - WHOLE-NERVE AP

KW - GUINEA-PIG

KW - FREQUENCY SPECIFICITY

KW - CHINCHILLA COCHLEA

KW - EVOKED-POTENTIALS

KW - NORMAL-HEARING

U2 - 10.1159/000158537

DO - 10.1159/000158537

M3 - Journal article

VL - 14

SP - 88

EP - 97

JO - Audiology and Neurotology

JF - Audiology and Neurotology

SN - 1420-3030

IS - 2

ER -

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