Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Bacterial cell-to-cell communication : sorry, can't talk now - gone to lunch!
AU - Winzer, Klaus
AU - Hardie, Kim R.
AU - Williams, Paul
PY - 2002/4
Y1 - 2002/4
N2 - The identification of novel bacterial cell-to-cell communication (quorum sensing) systems based on diffusible signal molecules, such as indole and the LuxS autoinducer-2, requires discrimination between true signalling molecules and metabolites present in culture supernatants. This depends on rigorous chemical characterisation and demonstration that the molecule controls cellular responses beyond those required to metabolise or detoxify the signal.
AB - The identification of novel bacterial cell-to-cell communication (quorum sensing) systems based on diffusible signal molecules, such as indole and the LuxS autoinducer-2, requires discrimination between true signalling molecules and metabolites present in culture supernatants. This depends on rigorous chemical characterisation and demonstration that the molecule controls cellular responses beyond those required to metabolise or detoxify the signal.
KW - quorum sensing
KW - autoinducer
KW - cell-to-cell signaling
KW - conditioned medium
KW - LuxS
KW - AI-2
KW - signal molecule
U2 - 10.1016/S1369-5274(02)00304-1
DO - 10.1016/S1369-5274(02)00304-1
M3 - Journal article
VL - 5
SP - 216
EP - 222
JO - Current Opinion in Microbiology
JF - Current Opinion in Microbiology
SN - 1369-5274
IS - 2
ER -