The blockchain is fascinating in many areas such as finance, healthcare, governance, security and many more. The underlying principle of the blockchain is based on distributed ledgers that solves many existing problems. Every blockchain framework has a different objective and application. There are many important criteria that must be considered during the selection of blockchain framework. Every blockchain framework and development platform has different pros and cons. In this chapter we present some of the leading enterprise frameworks for implementing blockchain solution. The enterprise support, pros and cons and transaction model are few important parameters to select the framework. In this chapter we present detailed investigation on blockchain frameworks that are publicly available.