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  • CellSheetsInCellTherapies

    Rights statement: This is the author’s version of a work that was accepted for publication in Cytotherapy. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Cytotherapy, 20, 2, 2018 DOI: 10.1016/j.jcyt.2017.11.004

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Cell sheets in cell therapies

Research output: Contribution to journalJournal articlepeer-review

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Cell sheets in cell therapies. / Kirby, Giles T.S.; Michelmore, Andrew; Smith, Louise E.; Whittle, Jason D.; Short, Robert D.

In: Cytotherapy, Vol. 20, No. 2, 02.2018, p. 169-180.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Kirby, GTS, Michelmore, A, Smith, LE, Whittle, JD & Short, RD 2018, 'Cell sheets in cell therapies', Cytotherapy, vol. 20, no. 2, pp. 169-180. https://doi.org/10.1016/j.jcyt.2017.11.004

APA

Kirby, G. T. S., Michelmore, A., Smith, L. E., Whittle, J. D., & Short, R. D. (2018). Cell sheets in cell therapies. Cytotherapy, 20(2), 169-180. https://doi.org/10.1016/j.jcyt.2017.11.004

Vancouver

Kirby GTS, Michelmore A, Smith LE, Whittle JD, Short RD. Cell sheets in cell therapies. Cytotherapy. 2018 Feb;20(2):169-180. https://doi.org/10.1016/j.jcyt.2017.11.004

Author

Kirby, Giles T.S. ; Michelmore, Andrew ; Smith, Louise E. ; Whittle, Jason D. ; Short, Robert D. / Cell sheets in cell therapies. In: Cytotherapy. 2018 ; Vol. 20, No. 2. pp. 169-180.

Bibtex

@article{c9b098231a20404bacee2c31cbaedd6d,
title = "Cell sheets in cell therapies",
abstract = "This review aims to provide a broad introduction to the use of cell sheets and the role of materials in the delivery of cell sheets to patients within a clinical setting. Traditionally, cells sheets have been, and currently are, fabricated using established and accepted cell culture methods within standard formats (e.g., petri dishes) utilizing biological substrates. Synthetic surfaces provide a far more versatile system for culturing and delivering cell sheets. This has the potential to positively affect quality, and efficient, localized cell delivery has a significant impact on patient outcome and on the overall cost of goods. We highlight current applications of these advanced carriers and future applications of these surfaces and cell sheets with an emphasis both on clinical use and regulatory requirements.",
keywords = "culture, plasma polymerization, regeneration, sheet, therapy",
author = "Kirby, {Giles T.S.} and Andrew Michelmore and Smith, {Louise E.} and Whittle, {Jason D.} and Short, {Robert D.}",
note = "This is the author{\textquoteright}s version of a work that was accepted for publication in Cytotherapy. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Cytotherapy, 20, 2, 2018 DOI: 10.1016/j.jcyt.2017.11.004",
year = "2018",
month = feb,
doi = "10.1016/j.jcyt.2017.11.004",
language = "English",
volume = "20",
pages = "169--180",
journal = "Cytotherapy",
issn = "1465-3249",
publisher = "Elsevier Inc.",
number = "2",

}

RIS

TY - JOUR

T1 - Cell sheets in cell therapies

AU - Kirby, Giles T.S.

AU - Michelmore, Andrew

AU - Smith, Louise E.

AU - Whittle, Jason D.

AU - Short, Robert D.

N1 - This is the author’s version of a work that was accepted for publication in Cytotherapy. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Cytotherapy, 20, 2, 2018 DOI: 10.1016/j.jcyt.2017.11.004

PY - 2018/2

Y1 - 2018/2

N2 - This review aims to provide a broad introduction to the use of cell sheets and the role of materials in the delivery of cell sheets to patients within a clinical setting. Traditionally, cells sheets have been, and currently are, fabricated using established and accepted cell culture methods within standard formats (e.g., petri dishes) utilizing biological substrates. Synthetic surfaces provide a far more versatile system for culturing and delivering cell sheets. This has the potential to positively affect quality, and efficient, localized cell delivery has a significant impact on patient outcome and on the overall cost of goods. We highlight current applications of these advanced carriers and future applications of these surfaces and cell sheets with an emphasis both on clinical use and regulatory requirements.

AB - This review aims to provide a broad introduction to the use of cell sheets and the role of materials in the delivery of cell sheets to patients within a clinical setting. Traditionally, cells sheets have been, and currently are, fabricated using established and accepted cell culture methods within standard formats (e.g., petri dishes) utilizing biological substrates. Synthetic surfaces provide a far more versatile system for culturing and delivering cell sheets. This has the potential to positively affect quality, and efficient, localized cell delivery has a significant impact on patient outcome and on the overall cost of goods. We highlight current applications of these advanced carriers and future applications of these surfaces and cell sheets with an emphasis both on clinical use and regulatory requirements.

KW - culture

KW - plasma polymerization

KW - regeneration

KW - sheet

KW - therapy

U2 - 10.1016/j.jcyt.2017.11.004

DO - 10.1016/j.jcyt.2017.11.004

M3 - Journal article

VL - 20

SP - 169

EP - 180

JO - Cytotherapy

JF - Cytotherapy

SN - 1465-3249

IS - 2

ER -