Characterisation of the inhomogeneity of sol–gel-derived SiO2–CaO bioactive glass and a strategy for its improvement

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Characterisation of the inhomogeneity of sol–gel-derived SiO2–CaO bioactive glass and a strategy for its improvement. / Lin, Sen; Ionescu, Claudia; Baker, Simon et al.
In: Journal of Sol-Gel Science and Technology, Vol. 53, No. 2, 02.2010, p. 255-262.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Lin, S, Ionescu, C, Baker, S, Smith, ME & Jones, JR 2010, 'Characterisation of the inhomogeneity of sol–gel-derived SiO2–CaO bioactive glass and a strategy for its improvement', Journal of Sol-Gel Science and Technology, vol. 53, no. 2, pp. 255-262. https://doi.org/10.1007/s10971-009-2085-0

APA

Lin, S., Ionescu, C., Baker, S., Smith, M. E., & Jones, J. R. (2010). Characterisation of the inhomogeneity of sol–gel-derived SiO2–CaO bioactive glass and a strategy for its improvement. Journal of Sol-Gel Science and Technology, 53(2), 255-262. https://doi.org/10.1007/s10971-009-2085-0

Vancouver

Lin S, Ionescu C, Baker S, Smith ME, Jones JR. Characterisation of the inhomogeneity of sol–gel-derived SiO2–CaO bioactive glass and a strategy for its improvement. Journal of Sol-Gel Science and Technology. 2010 Feb;53(2):255-262. doi: 10.1007/s10971-009-2085-0

Author

Lin, Sen ; Ionescu, Claudia ; Baker, Simon et al. / Characterisation of the inhomogeneity of sol–gel-derived SiO2–CaO bioactive glass and a strategy for its improvement. In: Journal of Sol-Gel Science and Technology. 2010 ; Vol. 53, No. 2. pp. 255-262.

Bibtex

@article{08bfd7d29d44428591afe6fb2588a743,

title = "Characterisation of the inhomogeneity of sol–gel-derived SiO2–CaO bioactive glass and a strategy for its improvement",

abstract = "Sol–gel derived bioactive glasses are one of the most promising materials for bone regeneration. The nanostructure of the glasses is critical regarding their interaction with the physiological environment. Composition is one of the most important factors affecting the nanostructure. In this study, inhomogeneity (a translucent component surrounded by an opaque component) was found within sol–gel derived bioactive glass monoliths (70 mol% SiO2 and 30 mol% CaO) produced by a standard procedure. The nanostructure and composition of the two components were characterised by electron microscopy, nitrogen sorption, secondary ion mass spectroscopy, X-ray fluorescence and solid state nuclear magnetic resonance. Results showed that calcium concentration and nanoscale porosity were much higher in the opaque region than in the translucent component. This is believed to be caused by calcium nitrate accumulation on the outer surface of the monoliths during the drying stage of the sol–gel process. The homogeneity of monoliths was successfully improved by using Teflon moulds. These findings are important for the large scale commercial production of homogeneous sol–gel glasses.",

keywords = "Sol–gel derived bioactive glasses , Calcium distribution, Homogeneity",

author = "Sen Lin and Claudia Ionescu and Simon Baker and Smith, {Mark E.} and Jones, {Julian R.}",

year = "2010",

month = feb,

doi = "10.1007/s10971-009-2085-0",

language = "English",

volume = "53",

pages = "255--262",

journal = "Journal of Sol-Gel Science and Technology",

issn = "1573-4846",

publisher = "Springer Netherlands",

number = "2",

}

RIS

TY - JOUR

T1 - Characterisation of the inhomogeneity of sol–gel-derived SiO2–CaO bioactive glass and a strategy for its improvement

AU - Lin, Sen

AU - Ionescu, Claudia

AU - Baker, Simon

AU - Smith, Mark E.

AU - Jones, Julian R.

PY - 2010/2

Y1 - 2010/2

N2 - Sol–gel derived bioactive glasses are one of the most promising materials for bone regeneration. The nanostructure of the glasses is critical regarding their interaction with the physiological environment. Composition is one of the most important factors affecting the nanostructure. In this study, inhomogeneity (a translucent component surrounded by an opaque component) was found within sol–gel derived bioactive glass monoliths (70 mol% SiO2 and 30 mol% CaO) produced by a standard procedure. The nanostructure and composition of the two components were characterised by electron microscopy, nitrogen sorption, secondary ion mass spectroscopy, X-ray fluorescence and solid state nuclear magnetic resonance. Results showed that calcium concentration and nanoscale porosity were much higher in the opaque region than in the translucent component. This is believed to be caused by calcium nitrate accumulation on the outer surface of the monoliths during the drying stage of the sol–gel process. The homogeneity of monoliths was successfully improved by using Teflon moulds. These findings are important for the large scale commercial production of homogeneous sol–gel glasses.

AB - Sol–gel derived bioactive glasses are one of the most promising materials for bone regeneration. The nanostructure of the glasses is critical regarding their interaction with the physiological environment. Composition is one of the most important factors affecting the nanostructure. In this study, inhomogeneity (a translucent component surrounded by an opaque component) was found within sol–gel derived bioactive glass monoliths (70 mol% SiO2 and 30 mol% CaO) produced by a standard procedure. The nanostructure and composition of the two components were characterised by electron microscopy, nitrogen sorption, secondary ion mass spectroscopy, X-ray fluorescence and solid state nuclear magnetic resonance. Results showed that calcium concentration and nanoscale porosity were much higher in the opaque region than in the translucent component. This is believed to be caused by calcium nitrate accumulation on the outer surface of the monoliths during the drying stage of the sol–gel process. The homogeneity of monoliths was successfully improved by using Teflon moulds. These findings are important for the large scale commercial production of homogeneous sol–gel glasses.

KW - Sol–gel derived bioactive glasses

KW - Calcium distribution

KW - Homogeneity

U2 - 10.1007/s10971-009-2085-0

DO - 10.1007/s10971-009-2085-0

M3 - Journal article

VL - 53

SP - 255

EP - 262

JO - Journal of Sol-Gel Science and Technology

JF - Journal of Sol-Gel Science and Technology

SN - 1573-4846

IS - 2

ER -

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