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Cold Plasma Generation of Peracetic Acid for Antimicrobial Applications

Research output: Contribution to Journal/MagazineJournal articlepeer-review

<mark>Journal publication date</mark>31/12/2021
<mark>Journal</mark>Plasma Medicine
Issue number4
Number of pages12
Pages (from-to)73-84
Publication StatusPublished
<mark>Original language</mark>English


This study compares how a helium plasma jet activates peracetic acid (PAA) from tetraacetylethylenediamine (TAED) and acetic acid (AA). Hydrogen peroxide (H 2 O 2 ) generated from the plasma jets reacts with TAED resulting in the formation of PAA which further dissoci-ates into AA. The by-product AA can also react with H 2 O 2 to form PAA, which might also be use-ful for antimicrobial applications when coupled with plasma. Equivalent concentrations of TAED and AA solutions are used to compare the formation of PAA after activation with a helium plasma jet. Our results showed that the concentrations of both H 2 O 2 and PAA in plasma-activated TAED (PAT) are higher than plasma-activated AA (PAAA), and that PAT is more efficient in reducing the growth of Pseudomonas aeruginosa and Staphylococcus aureus; the pathogens commonly found in wounds. The results are attributed to the presence of more acetyl donor groups in TAED, resulting in the formation of higher concentrations of PAA and H 2 O 2 .