Comparison of continuous sampling with active noise cancelation and sparse sampling for cortical and subcortical auditory functional MRI

Psychology

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https://doi.org/10.1002/mrm.28902
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Comparison of continuous sampling with active noise cancelation and sparse sampling for cortical and subcortical auditory functional MRI. / Dewey, R.S.; Hall, D.A.; Plack, C.J. et al.
In: Magnetic Resonance in Medicine, Vol. 86, No. 5, 30.11.2021, p. 2577-2588.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Bibtex

@article{bf789447141047cebeebe2e5a738694a,

title = "Comparison of continuous sampling with active noise cancelation and sparse sampling for cortical and subcortical auditory functional MRI",

abstract = "Purpose: Detecting sound-related activity using functional MRI requires the auditory stimulus to be more salient than the intense background scanner acoustic noise. Various strategies can reduce the impact of scanner acoustic noise, including “sparse” temporal sampling with single/clustered acquisitions providing intervals without any background scanner acoustic noise, or active noise cancelation (ANC) during “continuous” temporal sampling, which generates an acoustic signal that adds destructively to the scanner acoustic noise, substantially reducing the acoustic energy at the participant{\textquoteright}s eardrum. Furthermore, multiband functional MRI allows multiple slices to be collected simultaneously, thereby reducing scanner acoustic noise in a given sampling period. Methods: Isotropic multiband functional MRI (1.5 mm) with sparse sampling (effective TR = 9000 ms, acquisition duration = 1962 ms) and continuous sampling (TR = 2000 ms) with ANC were compared in 15 normally hearing participants. A sustained broadband noise stimulus was presented to drive activation of both sustained and transient auditory responses within subcortical and cortical auditory regions. Results: Robust broadband noise-related activity was detected throughout the auditory pathways. Continuous sampling with ANC was found to give a statistically significant advantage over sparse sampling for the detection of the transient (onset) stimulus responses, particularly in the auditory cortex (P < .001) and inferior colliculus (P < .001), whereas gains provided by sparse over continuous ANC for detecting offset and sustained responses were marginal (p ~ 0.05 in superior olivary complex, inferior colliculus, medial geniculate body, and auditory cortex). Conclusions Sparse and continuous ANC multiband functional MRI protocols provide differing advantages for observing the transient (onset and offset) and sustained stimulus responses.",

keywords = "auditory pathways, brainstem fMRI, functional magnetic resonance imaging, subcortical fMRI, Audition, Compressed sensing, Scanning, Acoustic signals, Auditory response, Auditory stimuli, Continuous sampling, Inferior colliculus, Stimulus response, Sustained response, Temporal sampling, Acoustic noise, adult, article, auditory cortex, auditory response, clinical article, controlled study, female, hearing, human, human experiment, human tissue, inferior colliculus, male, medial geniculate body, sensitivity analysis, stimulus response, superior olivary nucleus",

author = "R.S. Dewey and D.A. Hall and C.J. Plack and S.T. Francis",

year = "2021",

month = nov,

day = "30",

doi = "10.1002/mrm.28902",

language = "English",

volume = "86",

pages = "2577--2588",

journal = "Magnetic Resonance in Medicine",

number = "5",

}

RIS

TY - JOUR

T1 - Comparison of continuous sampling with active noise cancelation and sparse sampling for cortical and subcortical auditory functional MRI

AU - Dewey, R.S.

AU - Hall, D.A.

AU - Plack, C.J.

AU - Francis, S.T.

PY - 2021/11/30

Y1 - 2021/11/30

N2 - Purpose: Detecting sound-related activity using functional MRI requires the auditory stimulus to be more salient than the intense background scanner acoustic noise. Various strategies can reduce the impact of scanner acoustic noise, including “sparse” temporal sampling with single/clustered acquisitions providing intervals without any background scanner acoustic noise, or active noise cancelation (ANC) during “continuous” temporal sampling, which generates an acoustic signal that adds destructively to the scanner acoustic noise, substantially reducing the acoustic energy at the participant’s eardrum. Furthermore, multiband functional MRI allows multiple slices to be collected simultaneously, thereby reducing scanner acoustic noise in a given sampling period. Methods: Isotropic multiband functional MRI (1.5 mm) with sparse sampling (effective TR = 9000 ms, acquisition duration = 1962 ms) and continuous sampling (TR = 2000 ms) with ANC were compared in 15 normally hearing participants. A sustained broadband noise stimulus was presented to drive activation of both sustained and transient auditory responses within subcortical and cortical auditory regions. Results: Robust broadband noise-related activity was detected throughout the auditory pathways. Continuous sampling with ANC was found to give a statistically significant advantage over sparse sampling for the detection of the transient (onset) stimulus responses, particularly in the auditory cortex (P < .001) and inferior colliculus (P < .001), whereas gains provided by sparse over continuous ANC for detecting offset and sustained responses were marginal (p ~ 0.05 in superior olivary complex, inferior colliculus, medial geniculate body, and auditory cortex). Conclusions Sparse and continuous ANC multiband functional MRI protocols provide differing advantages for observing the transient (onset and offset) and sustained stimulus responses.

AB - Purpose: Detecting sound-related activity using functional MRI requires the auditory stimulus to be more salient than the intense background scanner acoustic noise. Various strategies can reduce the impact of scanner acoustic noise, including “sparse” temporal sampling with single/clustered acquisitions providing intervals without any background scanner acoustic noise, or active noise cancelation (ANC) during “continuous” temporal sampling, which generates an acoustic signal that adds destructively to the scanner acoustic noise, substantially reducing the acoustic energy at the participant’s eardrum. Furthermore, multiband functional MRI allows multiple slices to be collected simultaneously, thereby reducing scanner acoustic noise in a given sampling period. Methods: Isotropic multiband functional MRI (1.5 mm) with sparse sampling (effective TR = 9000 ms, acquisition duration = 1962 ms) and continuous sampling (TR = 2000 ms) with ANC were compared in 15 normally hearing participants. A sustained broadband noise stimulus was presented to drive activation of both sustained and transient auditory responses within subcortical and cortical auditory regions. Results: Robust broadband noise-related activity was detected throughout the auditory pathways. Continuous sampling with ANC was found to give a statistically significant advantage over sparse sampling for the detection of the transient (onset) stimulus responses, particularly in the auditory cortex (P < .001) and inferior colliculus (P < .001), whereas gains provided by sparse over continuous ANC for detecting offset and sustained responses were marginal (p ~ 0.05 in superior olivary complex, inferior colliculus, medial geniculate body, and auditory cortex). Conclusions Sparse and continuous ANC multiband functional MRI protocols provide differing advantages for observing the transient (onset and offset) and sustained stimulus responses.

KW - auditory pathways

KW - brainstem fMRI

KW - functional magnetic resonance imaging

KW - subcortical fMRI

KW - Audition

KW - Compressed sensing

KW - Scanning

KW - Acoustic signals

KW - Auditory response

KW - Auditory stimuli

KW - Continuous sampling

KW - Inferior colliculus

KW - Stimulus response

KW - Sustained response

KW - Temporal sampling

KW - Acoustic noise

KW - adult

KW - article

KW - auditory cortex

KW - auditory response

KW - clinical article

KW - controlled study

KW - female

KW - hearing

KW - human

KW - human experiment

KW - human tissue

KW - inferior colliculus

KW - male

KW - medial geniculate body

KW - sensitivity analysis

KW - stimulus response

KW - superior olivary nucleus

U2 - 10.1002/mrm.28902

DO - 10.1002/mrm.28902

M3 - Journal article

VL - 86

SP - 2577

EP - 2588

JO - Magnetic Resonance in Medicine

JF - Magnetic Resonance in Medicine

IS - 5

ER -

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