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Costs, effects and cost‐effectiveness of breast cancer control in Ghana

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Costs, effects and cost‐effectiveness of breast cancer control in Ghana. / Zelle, Sten G.; Nyarko, Kofi M.; Bosu, William K.; Aikins, Moses; Niëns, Laurens M.; Lauer, Jeremy A.; Sepulveda, Cecilia R.; Hontelez, Jan A. C.; Baltussen, Rob.

In: Tropical Medicine and International Health, Vol. 17, No. 8, 08.2012, p. 1031-1043.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Zelle, SG, Nyarko, KM, Bosu, WK, Aikins, M, Niëns, LM, Lauer, JA, Sepulveda, CR, Hontelez, JAC & Baltussen, R 2012, 'Costs, effects and cost‐effectiveness of breast cancer control in Ghana', Tropical Medicine and International Health, vol. 17, no. 8, pp. 1031-1043. https://doi.org/10.1111/j.1365-3156.2012.03021.x

APA

Zelle, S. G., Nyarko, K. M., Bosu, W. K., Aikins, M., Niëns, L. M., Lauer, J. A., Sepulveda, C. R., Hontelez, J. A. C., & Baltussen, R. (2012). Costs, effects and cost‐effectiveness of breast cancer control in Ghana. Tropical Medicine and International Health, 17(8), 1031-1043. https://doi.org/10.1111/j.1365-3156.2012.03021.x

Vancouver

Zelle SG, Nyarko KM, Bosu WK, Aikins M, Niëns LM, Lauer JA et al. Costs, effects and cost‐effectiveness of breast cancer control in Ghana. Tropical Medicine and International Health. 2012 Aug;17(8):1031-1043. https://doi.org/10.1111/j.1365-3156.2012.03021.x

Author

Zelle, Sten G. ; Nyarko, Kofi M. ; Bosu, William K. ; Aikins, Moses ; Niëns, Laurens M. ; Lauer, Jeremy A. ; Sepulveda, Cecilia R. ; Hontelez, Jan A. C. ; Baltussen, Rob. / Costs, effects and cost‐effectiveness of breast cancer control in Ghana. In: Tropical Medicine and International Health. 2012 ; Vol. 17, No. 8. pp. 1031-1043.

Bibtex

@article{4c221e88639942a7817631d86d4fe151,
title = "Costs, effects and cost‐effectiveness of breast cancer control in Ghana",
abstract = "Breast cancer control in Ghana is characterised by low awareness, late‐stage treatment and poor survival. In settings with severely constrained health resources, there is a need to spend money wisely. To achieve this and to guide policy makers in their selection of interventions, this study systematically compares costs and effects of breast cancer control interventions in Ghana. We used a mathematical model to estimate costs and health effects of breast cancer interventions in Ghana from the healthcare perspective. Analyses were based on the WHO‐CHOICE method, with health effects expressed in disability‐adjusted life years (DALYs), costs in 2009 US dollars (US$) and cost‐effectiveness ratios (CERs) in US$ per DALY averted. Analyses were based on local demographic, epidemiological and economic data, to the extent these data were available. Biennial screening by clinical breast examination (CBE) of women aged 40–69 years, in combination with treatment of all stages, seems the most cost‐effective intervention (costing $1299 per DALY averted). The intervention is also economically attractive according to international standards on cost‐effectiveness. Mass media awareness raising (MAR) is the second best option (costing $1364 per DALY averted). Mammography screening of women of aged 40–69 years (costing $12 908 per DALY averted) cannot be considered cost‐effective. Both CBE screening and MAR seem economically attractive interventions. Given the uncertainty about the effectiveness of these interventions, only their phased introduction, carefully monitored and evaluated, is warranted. Moreover, their implementation is only meaningful if the capacity of basic cancer diagnostic, referral and treatment and possibly palliative services is simultaneously improved.",
keywords = "Breast Cancer, Developing Countries, Cost‐Effectiveness, Ghana Policy, Non‐Communicable Diseases, Cancer Du Sein, Pays En D{\'e}veloppement, Co{\^u}t‐Efficacit{\'e}, Politique, Ghana, Maladies Non Transmissibles, C{\'a}ncer De Mama, Pa{\'i}ses En V{\'i}as De Desarrollo, Coste Efectividad, Pol{\'i}ticas, Enfermedades No Contagiosas",
author = "Zelle, {Sten G.} and Nyarko, {Kofi M.} and Bosu, {William K.} and Moses Aikins and Ni{\"e}ns, {Laurens M.} and Lauer, {Jeremy A.} and Sepulveda, {Cecilia R.} and Hontelez, {Jan A. C.} and Rob Baltussen",
year = "2012",
month = aug,
doi = "10.1111/j.1365-3156.2012.03021.x",
language = "English",
volume = "17",
pages = "1031--1043",
journal = "Tropical Medicine and International Health",
issn = "1360-2276",
publisher = "Wiley-Blackwell",
number = "8",

}

RIS

TY - JOUR

T1 - Costs, effects and cost‐effectiveness of breast cancer control in Ghana

AU - Zelle, Sten G.

AU - Nyarko, Kofi M.

AU - Bosu, William K.

AU - Aikins, Moses

AU - Niëns, Laurens M.

AU - Lauer, Jeremy A.

AU - Sepulveda, Cecilia R.

AU - Hontelez, Jan A. C.

AU - Baltussen, Rob

PY - 2012/8

Y1 - 2012/8

N2 - Breast cancer control in Ghana is characterised by low awareness, late‐stage treatment and poor survival. In settings with severely constrained health resources, there is a need to spend money wisely. To achieve this and to guide policy makers in their selection of interventions, this study systematically compares costs and effects of breast cancer control interventions in Ghana. We used a mathematical model to estimate costs and health effects of breast cancer interventions in Ghana from the healthcare perspective. Analyses were based on the WHO‐CHOICE method, with health effects expressed in disability‐adjusted life years (DALYs), costs in 2009 US dollars (US$) and cost‐effectiveness ratios (CERs) in US$ per DALY averted. Analyses were based on local demographic, epidemiological and economic data, to the extent these data were available. Biennial screening by clinical breast examination (CBE) of women aged 40–69 years, in combination with treatment of all stages, seems the most cost‐effective intervention (costing $1299 per DALY averted). The intervention is also economically attractive according to international standards on cost‐effectiveness. Mass media awareness raising (MAR) is the second best option (costing $1364 per DALY averted). Mammography screening of women of aged 40–69 years (costing $12 908 per DALY averted) cannot be considered cost‐effective. Both CBE screening and MAR seem economically attractive interventions. Given the uncertainty about the effectiveness of these interventions, only their phased introduction, carefully monitored and evaluated, is warranted. Moreover, their implementation is only meaningful if the capacity of basic cancer diagnostic, referral and treatment and possibly palliative services is simultaneously improved.

AB - Breast cancer control in Ghana is characterised by low awareness, late‐stage treatment and poor survival. In settings with severely constrained health resources, there is a need to spend money wisely. To achieve this and to guide policy makers in their selection of interventions, this study systematically compares costs and effects of breast cancer control interventions in Ghana. We used a mathematical model to estimate costs and health effects of breast cancer interventions in Ghana from the healthcare perspective. Analyses were based on the WHO‐CHOICE method, with health effects expressed in disability‐adjusted life years (DALYs), costs in 2009 US dollars (US$) and cost‐effectiveness ratios (CERs) in US$ per DALY averted. Analyses were based on local demographic, epidemiological and economic data, to the extent these data were available. Biennial screening by clinical breast examination (CBE) of women aged 40–69 years, in combination with treatment of all stages, seems the most cost‐effective intervention (costing $1299 per DALY averted). The intervention is also economically attractive according to international standards on cost‐effectiveness. Mass media awareness raising (MAR) is the second best option (costing $1364 per DALY averted). Mammography screening of women of aged 40–69 years (costing $12 908 per DALY averted) cannot be considered cost‐effective. Both CBE screening and MAR seem economically attractive interventions. Given the uncertainty about the effectiveness of these interventions, only their phased introduction, carefully monitored and evaluated, is warranted. Moreover, their implementation is only meaningful if the capacity of basic cancer diagnostic, referral and treatment and possibly palliative services is simultaneously improved.

KW - Breast Cancer

KW - Developing Countries

KW - Cost‐Effectiveness

KW - Ghana Policy

KW - Non‐Communicable Diseases

KW - Cancer Du Sein

KW - Pays En Développement

KW - Coût‐Efficacité

KW - Politique

KW - Ghana

KW - Maladies Non Transmissibles

KW - Cáncer De Mama

KW - Países En Vías De Desarrollo

KW - Coste Efectividad

KW - Políticas

KW - Enfermedades No Contagiosas

U2 - 10.1111/j.1365-3156.2012.03021.x

DO - 10.1111/j.1365-3156.2012.03021.x

M3 - Journal article

VL - 17

SP - 1031

EP - 1043

JO - Tropical Medicine and International Health

JF - Tropical Medicine and International Health

SN - 1360-2276

IS - 8

ER -