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Cytocompatibility evaluation of surface modified Ni-Ti shape memory alloy using the MTT assay

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Cytocompatibility evaluation of surface modified Ni-Ti shape memory alloy using the MTT assay. / Green, S. M.; Grant, D. M.; Wood, J. V.
In: Biomedical Engineering - Applications, Basis and Communications, Vol. 12, No. 2, 25.04.2000, p. 55-59.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Green, SM, Grant, DM & Wood, JV 2000, 'Cytocompatibility evaluation of surface modified Ni-Ti shape memory alloy using the MTT assay', Biomedical Engineering - Applications, Basis and Communications, vol. 12, no. 2, pp. 55-59.

APA

Green, S. M., Grant, D. M., & Wood, J. V. (2000). Cytocompatibility evaluation of surface modified Ni-Ti shape memory alloy using the MTT assay. Biomedical Engineering - Applications, Basis and Communications, 12(2), 55-59.

Vancouver

Green SM, Grant DM, Wood JV. Cytocompatibility evaluation of surface modified Ni-Ti shape memory alloy using the MTT assay. Biomedical Engineering - Applications, Basis and Communications. 2000 Apr 25;12(2):55-59.

Author

Green, S. M. ; Grant, D. M. ; Wood, J. V. / Cytocompatibility evaluation of surface modified Ni-Ti shape memory alloy using the MTT assay. In: Biomedical Engineering - Applications, Basis and Communications. 2000 ; Vol. 12, No. 2. pp. 55-59.

Bibtex

@article{fb7ce5ec29084027981b98a0a1cac6f5,
title = "Cytocompatibility evaluation of surface modified Ni-Ti shape memory alloy using the MTT assay",
abstract = "The cytocompatibility of N+ ion implanted and shot peen surface amorphised Ni-Ti shape memory alloy has been evaluated using the MTT cytotoxicity assay over 48 hours of 3T3 fibroblast contact and growth. In addition, SEM morphological examination and wetting behaviour measurements with full culture media were made. The modified Ni-Ti surfaces did not induce a cytotoxic response over the examination period and the SEM direct observation showed normal morphologies of cells grown upon the Ni-Ti surfaces. These results indicate that the adherent Ti-O2 rich surface film present on unmodified Ni-Ti is preserved during surface modification. Furthermore, the ion implanted surfaces showed enhanced cellular attachment, which is speculated to be a consequence of modified surface charge distribution.",
keywords = "Biocompatibility, Ion implantation, MTT cytotoxicity assay, Ni-Ti shape memory alloy, Surface modification",
author = "Green, {S. M.} and Grant, {D. M.} and Wood, {J. V.}",
year = "2000",
month = apr,
day = "25",
language = "English",
volume = "12",
pages = "55--59",
journal = "Biomedical Engineering - Applications, Basis and Communications",
issn = "1016-2372",
publisher = "World Scientific Publishing Co. Pte Ltd",
number = "2",

}

RIS

TY - JOUR

T1 - Cytocompatibility evaluation of surface modified Ni-Ti shape memory alloy using the MTT assay

AU - Green, S. M.

AU - Grant, D. M.

AU - Wood, J. V.

PY - 2000/4/25

Y1 - 2000/4/25

N2 - The cytocompatibility of N+ ion implanted and shot peen surface amorphised Ni-Ti shape memory alloy has been evaluated using the MTT cytotoxicity assay over 48 hours of 3T3 fibroblast contact and growth. In addition, SEM morphological examination and wetting behaviour measurements with full culture media were made. The modified Ni-Ti surfaces did not induce a cytotoxic response over the examination period and the SEM direct observation showed normal morphologies of cells grown upon the Ni-Ti surfaces. These results indicate that the adherent Ti-O2 rich surface film present on unmodified Ni-Ti is preserved during surface modification. Furthermore, the ion implanted surfaces showed enhanced cellular attachment, which is speculated to be a consequence of modified surface charge distribution.

AB - The cytocompatibility of N+ ion implanted and shot peen surface amorphised Ni-Ti shape memory alloy has been evaluated using the MTT cytotoxicity assay over 48 hours of 3T3 fibroblast contact and growth. In addition, SEM morphological examination and wetting behaviour measurements with full culture media were made. The modified Ni-Ti surfaces did not induce a cytotoxic response over the examination period and the SEM direct observation showed normal morphologies of cells grown upon the Ni-Ti surfaces. These results indicate that the adherent Ti-O2 rich surface film present on unmodified Ni-Ti is preserved during surface modification. Furthermore, the ion implanted surfaces showed enhanced cellular attachment, which is speculated to be a consequence of modified surface charge distribution.

KW - Biocompatibility

KW - Ion implantation

KW - MTT cytotoxicity assay

KW - Ni-Ti shape memory alloy

KW - Surface modification

M3 - Journal article

AN - SCOPUS:0034712636

VL - 12

SP - 55

EP - 59

JO - Biomedical Engineering - Applications, Basis and Communications

JF - Biomedical Engineering - Applications, Basis and Communications

SN - 1016-2372

IS - 2

ER -