Final published version
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Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA
AU - Hirsch, Mauro Mozael
AU - Deckmann, Iohanna
AU - Fontes-Dutra, Mellanie
AU - Bauer-Negrini, Guilherme
AU - Nunes, Gustavo Della-Flora
AU - Nunes, Walquiria
AU - Rabelo, Bruna
AU - Riesgo, Rudimar
AU - Margis, Rogerio
AU - Bambini-Junior, Victorio
AU - Gottfried, Carmem
PY - 2018/6/30
Y1 - 2018/6/30
N2 - This article contains data of Social Transmission of Food Preference in an animal model of autism and the evaluation of a set of microRNA analyzed in autistic patients and animal model of autism. The analyses of the absolute consumption of two flavored food by male rats prenatally exposed to valproic acid (VPA) and treated with resveratrol (RSV), showed that VPA animals show a trend to eat less of the flavored food presented by a demonstrator rat. We also identified 13 microRNA with similar levels among rodents' experimental groups, as well as 11 microRNA with no alterations between autistic and control subjects. Further evaluation of mechanisms of VPA and RSV actions on behavioral and molecular alterations can shed light in important biomarkers and etiological triggers of autistic spectrum disorders.
AB - This article contains data of Social Transmission of Food Preference in an animal model of autism and the evaluation of a set of microRNA analyzed in autistic patients and animal model of autism. The analyses of the absolute consumption of two flavored food by male rats prenatally exposed to valproic acid (VPA) and treated with resveratrol (RSV), showed that VPA animals show a trend to eat less of the flavored food presented by a demonstrator rat. We also identified 13 microRNA with similar levels among rodents' experimental groups, as well as 11 microRNA with no alterations between autistic and control subjects. Further evaluation of mechanisms of VPA and RSV actions on behavioral and molecular alterations can shed light in important biomarkers and etiological triggers of autistic spectrum disorders.
KW - Autism
KW - Social transmission of food preference
KW - microRNA
KW - Resveratrol
KW - Translational research
KW - Preclinical models
KW - Valproate
U2 - 10.1016/j.dib.2018.04.047
DO - 10.1016/j.dib.2018.04.047
M3 - Journal article
C2 - 29904648
VL - 18
SP - 1433
EP - 1440
JO - Data Brief
JF - Data Brief
SN - 2352-3409
ER -