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Determination of polychlorinated biphenyls in human foodstuffs and tissues: Suggestions for a selective congener analytical approach

Research output: Contribution to Journal/MagazineJournal articlepeer-review

<mark>Journal publication date</mark>1/01/1988
<mark>Journal</mark>Science of the Total Environment, The
Issue numberC
Number of pages19
Pages (from-to)141-159
Publication StatusPublished
<mark>Original language</mark>English


Based on a literature review of the occurrence of polychlorinated biphenyl (PCB) congeners in commercial formulations, environmental and biological samples and human tissues, and a consideration of the relative toxicity and persistence of the congeners, suggestions are made as to the most relevant components to be quantified by a selective congener analytical approach to human foodstuffs and tissues. These criteria suggest congener numbers 28, 74, 77, 99, 105, 118, 126, 128, 138, 153, 156, 169, 170, 179 and 180 will give a measure of > 70% of the total PCB tissue burden in a sample and be of greatest toxicological significance. Additionally, congeners 8, 37, 44, 49, 52, 60, 66, 70, 82, 87, 101, 114, 158, 166, 183, 187 and 189 are considered because of their reported occurrence or toxicity.