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Differentiated regions of human placental cell surface associated with attachment of chorionic villi, phagocytosis of maternal erythrocytes and syncytiotrophoblast repair

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Differentiated regions of human placental cell surface associated with attachment of chorionic villi, phagocytosis of maternal erythrocytes and syncytiotrophoblast repair. / Clint, J M; Wakely, J; Ockleford, C D.

In: Proceedings of the Royal Society of London. Series B, Vol. 204, No. 1156, 05.1979, p. 345-353.

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Clint, J M ; Wakely, J ; Ockleford, C D. / Differentiated regions of human placental cell surface associated with attachment of chorionic villi, phagocytosis of maternal erythrocytes and syncytiotrophoblast repair. In: Proceedings of the Royal Society of London. Series B. 1979 ; Vol. 204, No. 1156. pp. 345-353.

Bibtex

@article{ea3c34642b564a9694302b5f337ee70d,
title = "Differentiated regions of human placental cell surface associated with attachment of chorionic villi, phagocytosis of maternal erythrocytes and syncytiotrophoblast repair",
abstract = "Scanning electron micrographs of human placental cell surface show: (1) Differentiated zones of trophoblast which may be covered by fewer 'microvilli' than the adjacent syncytial cell surface and which extend as a narrow, usually distal protrusion of the chorionic villus. This narrow outgrowth terminates as a fractured end. Presumably since preparations were obtained from therapeutic terminations of pregnancy or Caesarian deliveries these broken ends represent the yield point in the anchoring 'villi' ruptured as a result of surgery. Similar anchoring 'villi' with fractured ends were observed in unfixed material with the use of Nomarski interference contrast microscopy. (2) It appears that, during apparent phagocytic uptake of maternal erythrocytes by syncytiotrophoblast, cell surface lining the forming vacuole still retains an irregular microvillous surface. This observation indicates the potential location of phagocytosis receptors for red blood cells in the placental cell surface. (3) Areas of human placenta which appears to have been damaged and may be undergoing repair exhibit masses of cells with conspicuous microvillar cell surfaces. The origin of these cells is discussed in relation to the usual processes of syncytiotrophoblast formation.",
keywords = "Cell Membrane, Erythrocytes, Female, Humans, Microscopy, Electron, Scanning, Microvilli, Phagocytosis, Placenta, Pregnancy",
author = "Clint, {J M} and J Wakely and Ockleford, {C D}",
year = "1979",
month = may,
doi = "10.1098/rspb.1979.0031",
language = "English",
volume = "204",
pages = "345--353",
journal = "Proceedings of the Royal Society of London. Series B",
issn = "0080-4649",
number = "1156",

}

RIS

TY - JOUR

T1 - Differentiated regions of human placental cell surface associated with attachment of chorionic villi, phagocytosis of maternal erythrocytes and syncytiotrophoblast repair

AU - Clint, J M

AU - Wakely, J

AU - Ockleford, C D

PY - 1979/5

Y1 - 1979/5

N2 - Scanning electron micrographs of human placental cell surface show: (1) Differentiated zones of trophoblast which may be covered by fewer 'microvilli' than the adjacent syncytial cell surface and which extend as a narrow, usually distal protrusion of the chorionic villus. This narrow outgrowth terminates as a fractured end. Presumably since preparations were obtained from therapeutic terminations of pregnancy or Caesarian deliveries these broken ends represent the yield point in the anchoring 'villi' ruptured as a result of surgery. Similar anchoring 'villi' with fractured ends were observed in unfixed material with the use of Nomarski interference contrast microscopy. (2) It appears that, during apparent phagocytic uptake of maternal erythrocytes by syncytiotrophoblast, cell surface lining the forming vacuole still retains an irregular microvillous surface. This observation indicates the potential location of phagocytosis receptors for red blood cells in the placental cell surface. (3) Areas of human placenta which appears to have been damaged and may be undergoing repair exhibit masses of cells with conspicuous microvillar cell surfaces. The origin of these cells is discussed in relation to the usual processes of syncytiotrophoblast formation.

AB - Scanning electron micrographs of human placental cell surface show: (1) Differentiated zones of trophoblast which may be covered by fewer 'microvilli' than the adjacent syncytial cell surface and which extend as a narrow, usually distal protrusion of the chorionic villus. This narrow outgrowth terminates as a fractured end. Presumably since preparations were obtained from therapeutic terminations of pregnancy or Caesarian deliveries these broken ends represent the yield point in the anchoring 'villi' ruptured as a result of surgery. Similar anchoring 'villi' with fractured ends were observed in unfixed material with the use of Nomarski interference contrast microscopy. (2) It appears that, during apparent phagocytic uptake of maternal erythrocytes by syncytiotrophoblast, cell surface lining the forming vacuole still retains an irregular microvillous surface. This observation indicates the potential location of phagocytosis receptors for red blood cells in the placental cell surface. (3) Areas of human placenta which appears to have been damaged and may be undergoing repair exhibit masses of cells with conspicuous microvillar cell surfaces. The origin of these cells is discussed in relation to the usual processes of syncytiotrophoblast formation.

KW - Cell Membrane

KW - Erythrocytes

KW - Female

KW - Humans

KW - Microscopy, Electron, Scanning

KW - Microvilli

KW - Phagocytosis

KW - Placenta

KW - Pregnancy

U2 - 10.1098/rspb.1979.0031

DO - 10.1098/rspb.1979.0031

M3 - Journal article

C2 - 37520

VL - 204

SP - 345

EP - 353

JO - Proceedings of the Royal Society of London. Series B

JF - Proceedings of the Royal Society of London. Series B

SN - 0080-4649

IS - 1156

ER -