TY - JOUR

T1 - Differentiated regions of human placental cell surface associated with exchange of materials between maternal and fetal blood coated vesicles

AU - Ockleford, Colin Douglas

AU - Whyte, A

PY - 1977/1/1

Y1 - 1977/1/1

N2 - Forming and mature human placental coated vesicles contained thickened regions of glycocalyx which were absent from other regions of the cell surface. Over 98% of vesicles lay within the diameter of the largest vesicle from the cell surface. Negative staining confirmed earlier description of polygonally patterned structures on the cytoplasmic surface of placental coated vesicles based on goniometry of ultrathin sectioned material. A 180,000 MW protein from an isolated fraction of coated vesicles probably represented vesicle surface structure protein clathrin which had not previously been identified in any human or placental tissue.

AB - Forming and mature human placental coated vesicles contained thickened regions of glycocalyx which were absent from other regions of the cell surface. Over 98% of vesicles lay within the diameter of the largest vesicle from the cell surface. Negative staining confirmed earlier description of polygonally patterned structures on the cytoplasmic surface of placental coated vesicles based on goniometry of ultrathin sectioned material. A 180,000 MW protein from an isolated fraction of coated vesicles probably represented vesicle surface structure protein clathrin which had not previously been identified in any human or placental tissue.

M3 - Journal article

VL - 25

SP - 293

EP - 312

JO - Journal of Cell Science

JF - Journal of Cell Science

SN - 0021-9533

ER -