TY - JOUR

T1 - Disposable injection-moulded cell-on-a-chip microfluidic devices with integrated conducting polymer electrodes for on-line voltammetric and electrochemiluminescence detection

AU - Naseri, N. Gharib

AU - Baldock, Sara J.

AU - Economou, A.

AU - Goddard, Nick J.

AU - Fielden, Peter R.

PY - 2008/2

Y1 - 2008/2

N2 - This work reports the construction and characterization of plastic electrochemical micro-flow-cells with integrated injection-moulded polymer electrodes. The three electrodes (working, auxiliary, and reference) were fabricated by injection-moulding from a conducting grade of polystyrene loaded with carbon fibers. On-chip reference electrodes were prepared by coating one of the conducting polymer electrodes with a Ag/AgCl layer (implemented either by e-beam evaporation of Ag followed by electrochemical formation of AgCl or by applying a Ag/AgCl paste). Working electrodes were either polymer electrodes coated with Au by e-beam evaporation or bare conducting polymer electrodes. The electrodes were integrated into the micro-flow-cells by an over-moulding process followed by ultrasonic welding. The devices were characterized by optical and electrochemical techniques. Studies by cyclic voltammetry (CV), anodic stripping voltammetry (ASV) and electrochemiluminescence (ECL) demonstrate ‘proof–of-principle’ of the micro-flow-cells as electrochemical sensors.

AB - This work reports the construction and characterization of plastic electrochemical micro-flow-cells with integrated injection-moulded polymer electrodes. The three electrodes (working, auxiliary, and reference) were fabricated by injection-moulding from a conducting grade of polystyrene loaded with carbon fibers. On-chip reference electrodes were prepared by coating one of the conducting polymer electrodes with a Ag/AgCl layer (implemented either by e-beam evaporation of Ag followed by electrochemical formation of AgCl or by applying a Ag/AgCl paste). Working electrodes were either polymer electrodes coated with Au by e-beam evaporation or bare conducting polymer electrodes. The electrodes were integrated into the micro-flow-cells by an over-moulding process followed by ultrasonic welding. The devices were characterized by optical and electrochemical techniques. Studies by cyclic voltammetry (CV), anodic stripping voltammetry (ASV) and electrochemiluminescence (ECL) demonstrate ‘proof–of-principle’ of the micro-flow-cells as electrochemical sensors.

U2 - 10.1002/elan.200704074

DO - 10.1002/elan.200704074

M3 - Journal article

VL - 20

SP - 448

EP - 454

JO - Electroanalysis

JF - Electroanalysis

SN - 1040-0397

IS - 4

ER -