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Drug shortages: A systems view of the current state

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Drug shortages: A systems view of the current state. / Van Oorschot, Kim; Van Wassenhove, Luk; Jahre, Marianne et al.
In: Decision Sciences, Vol. 53, No. 6, 31.12.2022, p. 969-984.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Harvard

Van Oorschot, K, Van Wassenhove, L, Jahre, M, Selviaridis, K & de Vries, H 2022, 'Drug shortages: A systems view of the current state', Decision Sciences, vol. 53, no. 6, pp. 969-984. https://doi.org/10.1111/deci.12583

APA

Van Oorschot, K., Van Wassenhove, L., Jahre, M., Selviaridis, K., & de Vries, H. (2022). Drug shortages: A systems view of the current state. Decision Sciences, 53(6), 969-984. https://doi.org/10.1111/deci.12583

Vancouver

Van Oorschot K, Van Wassenhove L, Jahre M, Selviaridis K, de Vries H. Drug shortages: A systems view of the current state. Decision Sciences. 2022 Dec 31;53(6):969-984. Epub 2022 Oct 17. doi: 10.1111/deci.12583

Author

Van Oorschot, Kim ; Van Wassenhove, Luk ; Jahre, Marianne et al. / Drug shortages : A systems view of the current state. In: Decision Sciences. 2022 ; Vol. 53, No. 6. pp. 969-984.

Bibtex

@article{23e427d7652b43feb812e566d1c6f860,
title = "Drug shortages: A systems view of the current state",
abstract = "The objective of this thought leadership article is to create a systems view of drug shortages based on the perceptions of practitioners and policymakers. We develop a comprehensive framework describing what stakeholders are currently doing when faced with drug shortages and show the outcomes of their actions. In a review of practitioner literature and public reports published from 2010 to 2020, we identify cause-and-effect relationships related to generic drug shortages in six high-income European countries (Belgium, France, the Netherlands, Norway, Sweden, and the UK) in normal times. By combining and connecting data from these different sources, we develop a systems view of the current state. Though several of the associations covered in the systems view are well known, putting them all together and considering their interrelationships is what is offered by this research. Based on this systems view, we derive three basic solution archetypes for drug shortages: (1) let the market handle it; (2) search for alternatives; and (3) bend the rules. The interactions between these archetypes generate causal ambiguity making it harder to understand and solve the problem as the side effects of solutions can be missed. We show how the interaction of archetypes can compromise intended behavior or escalate unintended behavior. However, our systems view allows us to suggest higher-level solution archetypes that overrule such side effects. The basic and higher-order solution archetypes can provide baselines for research and support the development of future interventions.",
author = "{Van Oorschot}, Kim and {Van Wassenhove}, Luk and Marianne Jahre and Kostas Selviaridis and {de Vries}, Harwin",
year = "2022",
month = dec,
day = "31",
doi = "10.1111/deci.12583",
language = "English",
volume = "53",
pages = "969--984",
journal = "Decision Sciences",
issn = "0011-7315",
publisher = "Wiley-Blackwell",
number = "6",

}

RIS

TY - JOUR

T1 - Drug shortages

T2 - A systems view of the current state

AU - Van Oorschot, Kim

AU - Van Wassenhove, Luk

AU - Jahre, Marianne

AU - Selviaridis, Kostas

AU - de Vries, Harwin

PY - 2022/12/31

Y1 - 2022/12/31

N2 - The objective of this thought leadership article is to create a systems view of drug shortages based on the perceptions of practitioners and policymakers. We develop a comprehensive framework describing what stakeholders are currently doing when faced with drug shortages and show the outcomes of their actions. In a review of practitioner literature and public reports published from 2010 to 2020, we identify cause-and-effect relationships related to generic drug shortages in six high-income European countries (Belgium, France, the Netherlands, Norway, Sweden, and the UK) in normal times. By combining and connecting data from these different sources, we develop a systems view of the current state. Though several of the associations covered in the systems view are well known, putting them all together and considering their interrelationships is what is offered by this research. Based on this systems view, we derive three basic solution archetypes for drug shortages: (1) let the market handle it; (2) search for alternatives; and (3) bend the rules. The interactions between these archetypes generate causal ambiguity making it harder to understand and solve the problem as the side effects of solutions can be missed. We show how the interaction of archetypes can compromise intended behavior or escalate unintended behavior. However, our systems view allows us to suggest higher-level solution archetypes that overrule such side effects. The basic and higher-order solution archetypes can provide baselines for research and support the development of future interventions.

AB - The objective of this thought leadership article is to create a systems view of drug shortages based on the perceptions of practitioners and policymakers. We develop a comprehensive framework describing what stakeholders are currently doing when faced with drug shortages and show the outcomes of their actions. In a review of practitioner literature and public reports published from 2010 to 2020, we identify cause-and-effect relationships related to generic drug shortages in six high-income European countries (Belgium, France, the Netherlands, Norway, Sweden, and the UK) in normal times. By combining and connecting data from these different sources, we develop a systems view of the current state. Though several of the associations covered in the systems view are well known, putting them all together and considering their interrelationships is what is offered by this research. Based on this systems view, we derive three basic solution archetypes for drug shortages: (1) let the market handle it; (2) search for alternatives; and (3) bend the rules. The interactions between these archetypes generate causal ambiguity making it harder to understand and solve the problem as the side effects of solutions can be missed. We show how the interaction of archetypes can compromise intended behavior or escalate unintended behavior. However, our systems view allows us to suggest higher-level solution archetypes that overrule such side effects. The basic and higher-order solution archetypes can provide baselines for research and support the development of future interventions.

U2 - 10.1111/deci.12583

DO - 10.1111/deci.12583

M3 - Journal article

VL - 53

SP - 969

EP - 984

JO - Decision Sciences

JF - Decision Sciences

SN - 0011-7315

IS - 6

ER -