We are faced with global challenges of new dimensions, most of which are interrelated. The majority are included in the United Nations 2030 Agenda for Sustainable Development. Knowledge is one of the key elements for achieving the 2030 Agenda. Universities play a vital role in contributing to sustainable development. However, we are currently faced with obstacles that prevent us from adding and sharing our knowledge efficiently and effectively. In this context, universities must change and reconsider their role in society. At the UOC, we are committed to transformation through becoming a knowledge hub. For that reason, we kicked of an Open Knowledge Action Plan which we present and analyse in this article.