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Engineered alternative skin for partial and full-thickness burns

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Engineered alternative skin for partial and full-thickness burns. / Wessels, Quenton.
In: Bioengineered, Vol. 5, No. 3, 05.2014, p. 161-164.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

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Wessels Q. Engineered alternative skin for partial and full-thickness burns. Bioengineered. 2014 May;5(3):161-164. Epub 2014 Mar 20. doi: 10.4161/bioe.28598

Author

Wessels, Quenton. / Engineered alternative skin for partial and full-thickness burns. In: Bioengineered. 2014 ; Vol. 5, No. 3. pp. 161-164.

Bibtex

@article{dbc0dd504c5841dba25ed0ae934d0047,
title = "Engineered alternative skin for partial and full-thickness burns",
abstract = "Engineered alternative skin in all its forms and shapes serve to provide temporary or permanent wound closure such as in the case of partial and full-thickness burns. The need for collagen-based regeneration templates is motivated by the fact that dermal regeneration of full-thickness injuries does not occur spontaneously and is inundated by contraction and scarring. Partial-thickness burns in turn can regress as a result of infection and improper treatment and require appropriate treatment. Nylon-silicone laminates such as Biobrane({\textregistered}), and more recently AWBAT({\textregistered}), address this by serving as a temporary barrier. Enhanced collagen-based scaffolds today, although not perfect, remain invaluable. Our initial approach was to characterize the design considerations and explore the use of collagen in the fabrication of a dermal regeneration matrix and a silicone-nylon bilaminate. Here we expand our initial research on scaffold fabrication and explore possible strategies to improve the outcome of collagen-scaffold medicated wound healing.",
author = "Quenton Wessels",
year = "2014",
month = may,
doi = "10.4161/bioe.28598",
language = "English",
volume = "5",
pages = "161--164",
journal = "Bioengineered",
issn = "2165-5987",
publisher = "Taylor and Francis Ltd.",
number = "3",

}

RIS

TY - JOUR

T1 - Engineered alternative skin for partial and full-thickness burns

AU - Wessels, Quenton

PY - 2014/5

Y1 - 2014/5

N2 - Engineered alternative skin in all its forms and shapes serve to provide temporary or permanent wound closure such as in the case of partial and full-thickness burns. The need for collagen-based regeneration templates is motivated by the fact that dermal regeneration of full-thickness injuries does not occur spontaneously and is inundated by contraction and scarring. Partial-thickness burns in turn can regress as a result of infection and improper treatment and require appropriate treatment. Nylon-silicone laminates such as Biobrane(®), and more recently AWBAT(®), address this by serving as a temporary barrier. Enhanced collagen-based scaffolds today, although not perfect, remain invaluable. Our initial approach was to characterize the design considerations and explore the use of collagen in the fabrication of a dermal regeneration matrix and a silicone-nylon bilaminate. Here we expand our initial research on scaffold fabrication and explore possible strategies to improve the outcome of collagen-scaffold medicated wound healing.

AB - Engineered alternative skin in all its forms and shapes serve to provide temporary or permanent wound closure such as in the case of partial and full-thickness burns. The need for collagen-based regeneration templates is motivated by the fact that dermal regeneration of full-thickness injuries does not occur spontaneously and is inundated by contraction and scarring. Partial-thickness burns in turn can regress as a result of infection and improper treatment and require appropriate treatment. Nylon-silicone laminates such as Biobrane(®), and more recently AWBAT(®), address this by serving as a temporary barrier. Enhanced collagen-based scaffolds today, although not perfect, remain invaluable. Our initial approach was to characterize the design considerations and explore the use of collagen in the fabrication of a dermal regeneration matrix and a silicone-nylon bilaminate. Here we expand our initial research on scaffold fabrication and explore possible strategies to improve the outcome of collagen-scaffold medicated wound healing.

U2 - 10.4161/bioe.28598

DO - 10.4161/bioe.28598

M3 - Journal article

C2 - 24651001

VL - 5

SP - 161

EP - 164

JO - Bioengineered

JF - Bioengineered

SN - 2165-5987

IS - 3

ER -