This position paper summarizes key results from the workshop “Professional Ethics at the End of Life” held from 27 May to 1 June 2019 in Greifswald (Germany). An international group of 13 young scholars from six countries and various healthcare-related disciplines (e.g. nursing, medicine, philosophy, theology, gerontology, psychology) met to discuss ethical issues in patient care at the end of life. A special focus of the workshop was on international comparisons and the roles and moral obligations of health-care professionals. The need for interprofessional dialogue and family involvement emerged as key factors for patient-centred, holistic care at the end of life. Further main results were collected from the participants subsequent to the workshop, arranged regarding content and further circulated and revised within the group. The position paper, therefore, represents the views of young health-care researchers and practitioners with respect to the current status and further perspectives of professionalism and interprofessional care at the end of life. It can serve as a starting point for scientific and political debates on moral obligations, professional practice and health-care structures.