Research output: Contribution to Journal/Magazine › Journal article › peer-review
| <mark>Journal publication date</mark> | 2011 |
|---|---|
| <mark>Journal</mark> | Organic and Biomolecular Chemistry |
| Issue number | 14 |
| Volume | 9 |
| Number of pages | 5 |
| Pages (from-to) | 5104-5108 |
| Publication Status | Published |
| <mark>Original language</mark> | English |
A tag removal-cyclisation sequence is described that is initiated by reduction using a Sm(II) species and completed by a Sm(III) Lewis acid that is formed in an earlier stage. Therefore, the reaction cascade utilises both oxidation states of a samarium reagent in discrete steps and allows access to privileged, pyrrolidinyl-spirooxindole scaffolds and analogues inspired by the anti-cancer natural product spirotryprostatin A.