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Eye Movement Desensitisation and Reprocessing Therapy for psychosis (EMDRp): Protocol of a feasibility randomised controlled trial with Early Intervention service users

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Eye Movement Desensitisation and Reprocessing Therapy for psychosis (EMDRp): Protocol of a feasibility randomised controlled trial with Early Intervention service users. / Varese, Filippo; Sellwood, Bill; Aseem, Saadia et al.
In: Early Intervention in Psychiatry, Vol. 15, No. 5, 31.10.2021, p. 1224-1233.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Harvard

Varese, F, Sellwood, B, Aseem, S, Awenat, Y, Bird, L, Bhutani, G, Carter, L-A, Davis, L, Horne, G, Keane, D, Logie, R, Malkin, D, Potter, F, van den Berg, D, Zia, S & Bentall, R 2021, 'Eye Movement Desensitisation and Reprocessing Therapy for psychosis (EMDRp): Protocol of a feasibility randomised controlled trial with Early Intervention service users', Early Intervention in Psychiatry, vol. 15, no. 5, pp. 1224-1233. https://doi.org/10.1111/eip.13071

APA

Varese, F., Sellwood, B., Aseem, S., Awenat, Y., Bird, L., Bhutani, G., Carter, L-A., Davis, L., Horne, G., Keane, D., Logie, R., Malkin, D., Potter, F., van den Berg, D., Zia, S., & Bentall, R. (2021). Eye Movement Desensitisation and Reprocessing Therapy for psychosis (EMDRp): Protocol of a feasibility randomised controlled trial with Early Intervention service users. Early Intervention in Psychiatry, 15(5), 1224-1233. https://doi.org/10.1111/eip.13071

Vancouver

Varese F, Sellwood B, Aseem S, Awenat Y, Bird L, Bhutani G et al. Eye Movement Desensitisation and Reprocessing Therapy for psychosis (EMDRp): Protocol of a feasibility randomised controlled trial with Early Intervention service users. Early Intervention in Psychiatry. 2021 Oct 31;15(5):1224-1233. Epub 2020 Nov 22. doi: 10.1111/eip.13071

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Bibtex

@article{7a8f0cfe45984f47889b8f914f4d26e5,
title = "Eye Movement Desensitisation and Reprocessing Therapy for psychosis (EMDRp): Protocol of a feasibility randomised controlled trial with Early Intervention service users",
abstract = "AbstractAim: Traumatic events are involved in the development and maintenance of psychotic symptoms. There are few trials exploring trauma-focused treatments as interventions for psychotic symptoms, especially in individuals with early psychosis. This trial will evaluate the feasibility and acceptability of conducting a definitive trial of Eye Movement Desensitisation and Reprocessing for psychosis (EMDRp) in people with early psychosis. Methods: 60 participants with first episode psychosis and a history of a traumatic/adverse life event(s) will be recruited from early intervention services in the North West of England and randomised to receive 16 sessions of EMDRp + Treatment as Usual (TAU) or TAU alone. Participants will be assessed at baseline, 6 months and 12 months post-randomisation using several measures of psychotic symptoms, trauma symptoms, anxiety, depression, functioning, service-user defined recovery, health economics indicators and quality of life. Two nested qualitative studies to assess participant feedback of therapy and views of professional stakeholders on the implementation of EMDRp into services will also be conducted. The feasibility of a future definitive efficacy and cost effectiveness evaluation of EMDRp will be tested against several outcomes, including ability to recruit and randomise participants, trial retention at 6- and 12-month follow-up assessments, treatment engagement and treatment fidelity. Conclusions: If it is feasible to deliver a multi-site trial of this intervention, it will be possible to evaluate whether EMDRp represents a beneficial treatment to augment existing evidence-based care of individuals with early psychosis supported by early intervention services.",
keywords = "EMDR, feasibility, psychosis, RCT, trauma",
author = "Filippo Varese and Bill Sellwood and Saadia Aseem and Yvonne Awenat and Leanne Bird and Gita Bhutani and Lesley-Anne Carter and Linda Davis and Georgia Horne and David Keane and Robin Logie and Debra Malkin and Fiona Potter and {van den Berg}, David and Shameem Zia and Richard Bentall",
year = "2021",
month = oct,
day = "31",
doi = "10.1111/eip.13071",
language = "English",
volume = "15",
pages = "1224--1233",
journal = "Early Intervention in Psychiatry",
issn = "1751-7885",
publisher = "Wiley",
number = "5",

}

RIS

TY - JOUR

T1 - Eye Movement Desensitisation and Reprocessing Therapy for psychosis (EMDRp)

T2 - Protocol of a feasibility randomised controlled trial with Early Intervention service users

AU - Varese, Filippo

AU - Sellwood, Bill

AU - Aseem, Saadia

AU - Awenat, Yvonne

AU - Bird, Leanne

AU - Bhutani, Gita

AU - Carter, Lesley-Anne

AU - Davis, Linda

AU - Horne, Georgia

AU - Keane, David

AU - Logie, Robin

AU - Malkin, Debra

AU - Potter, Fiona

AU - van den Berg, David

AU - Zia, Shameem

AU - Bentall, Richard

PY - 2021/10/31

Y1 - 2021/10/31

N2 - AbstractAim: Traumatic events are involved in the development and maintenance of psychotic symptoms. There are few trials exploring trauma-focused treatments as interventions for psychotic symptoms, especially in individuals with early psychosis. This trial will evaluate the feasibility and acceptability of conducting a definitive trial of Eye Movement Desensitisation and Reprocessing for psychosis (EMDRp) in people with early psychosis. Methods: 60 participants with first episode psychosis and a history of a traumatic/adverse life event(s) will be recruited from early intervention services in the North West of England and randomised to receive 16 sessions of EMDRp + Treatment as Usual (TAU) or TAU alone. Participants will be assessed at baseline, 6 months and 12 months post-randomisation using several measures of psychotic symptoms, trauma symptoms, anxiety, depression, functioning, service-user defined recovery, health economics indicators and quality of life. Two nested qualitative studies to assess participant feedback of therapy and views of professional stakeholders on the implementation of EMDRp into services will also be conducted. The feasibility of a future definitive efficacy and cost effectiveness evaluation of EMDRp will be tested against several outcomes, including ability to recruit and randomise participants, trial retention at 6- and 12-month follow-up assessments, treatment engagement and treatment fidelity. Conclusions: If it is feasible to deliver a multi-site trial of this intervention, it will be possible to evaluate whether EMDRp represents a beneficial treatment to augment existing evidence-based care of individuals with early psychosis supported by early intervention services.

AB - AbstractAim: Traumatic events are involved in the development and maintenance of psychotic symptoms. There are few trials exploring trauma-focused treatments as interventions for psychotic symptoms, especially in individuals with early psychosis. This trial will evaluate the feasibility and acceptability of conducting a definitive trial of Eye Movement Desensitisation and Reprocessing for psychosis (EMDRp) in people with early psychosis. Methods: 60 participants with first episode psychosis and a history of a traumatic/adverse life event(s) will be recruited from early intervention services in the North West of England and randomised to receive 16 sessions of EMDRp + Treatment as Usual (TAU) or TAU alone. Participants will be assessed at baseline, 6 months and 12 months post-randomisation using several measures of psychotic symptoms, trauma symptoms, anxiety, depression, functioning, service-user defined recovery, health economics indicators and quality of life. Two nested qualitative studies to assess participant feedback of therapy and views of professional stakeholders on the implementation of EMDRp into services will also be conducted. The feasibility of a future definitive efficacy and cost effectiveness evaluation of EMDRp will be tested against several outcomes, including ability to recruit and randomise participants, trial retention at 6- and 12-month follow-up assessments, treatment engagement and treatment fidelity. Conclusions: If it is feasible to deliver a multi-site trial of this intervention, it will be possible to evaluate whether EMDRp represents a beneficial treatment to augment existing evidence-based care of individuals with early psychosis supported by early intervention services.

KW - EMDR

KW - feasibility

KW - psychosis

KW - RCT

KW - trauma

U2 - 10.1111/eip.13071

DO - 10.1111/eip.13071

M3 - Journal article

VL - 15

SP - 1224

EP - 1233

JO - Early Intervention in Psychiatry

JF - Early Intervention in Psychiatry

SN - 1751-7885

IS - 5

ER -