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Research output: Contribution to Journal/Magazine › Journal article › peer-review
Eye Movement Desensitisation and Reprocessing Therapy for psychosis (EMDRp) : Protocol of a feasibility randomised controlled trial with Early Intervention service users. / Varese, Filippo; Sellwood, Bill; Aseem, Saadia et al.
In: Early Intervention in Psychiatry, Vol. 15, No. 5, 31.10.2021, p. 1224-1233.Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Eye Movement Desensitisation and Reprocessing Therapy for psychosis (EMDRp)
T2 - Protocol of a feasibility randomised controlled trial with Early Intervention service users
AU - Varese, Filippo
AU - Sellwood, Bill
AU - Aseem, Saadia
AU - Awenat, Yvonne
AU - Bird, Leanne
AU - Bhutani, Gita
AU - Carter, Lesley-Anne
AU - Davis, Linda
AU - Horne, Georgia
AU - Keane, David
AU - Logie, Robin
AU - Malkin, Debra
AU - Potter, Fiona
AU - van den Berg, David
AU - Zia, Shameem
AU - Bentall, Richard
PY - 2021/10/31
Y1 - 2021/10/31
N2 - AbstractAim: Traumatic events are involved in the development and maintenance of psychotic symptoms. There are few trials exploring trauma-focused treatments as interventions for psychotic symptoms, especially in individuals with early psychosis. This trial will evaluate the feasibility and acceptability of conducting a definitive trial of Eye Movement Desensitisation and Reprocessing for psychosis (EMDRp) in people with early psychosis. Methods: 60 participants with first episode psychosis and a history of a traumatic/adverse life event(s) will be recruited from early intervention services in the North West of England and randomised to receive 16 sessions of EMDRp + Treatment as Usual (TAU) or TAU alone. Participants will be assessed at baseline, 6 months and 12 months post-randomisation using several measures of psychotic symptoms, trauma symptoms, anxiety, depression, functioning, service-user defined recovery, health economics indicators and quality of life. Two nested qualitative studies to assess participant feedback of therapy and views of professional stakeholders on the implementation of EMDRp into services will also be conducted. The feasibility of a future definitive efficacy and cost effectiveness evaluation of EMDRp will be tested against several outcomes, including ability to recruit and randomise participants, trial retention at 6- and 12-month follow-up assessments, treatment engagement and treatment fidelity. Conclusions: If it is feasible to deliver a multi-site trial of this intervention, it will be possible to evaluate whether EMDRp represents a beneficial treatment to augment existing evidence-based care of individuals with early psychosis supported by early intervention services.
AB - AbstractAim: Traumatic events are involved in the development and maintenance of psychotic symptoms. There are few trials exploring trauma-focused treatments as interventions for psychotic symptoms, especially in individuals with early psychosis. This trial will evaluate the feasibility and acceptability of conducting a definitive trial of Eye Movement Desensitisation and Reprocessing for psychosis (EMDRp) in people with early psychosis. Methods: 60 participants with first episode psychosis and a history of a traumatic/adverse life event(s) will be recruited from early intervention services in the North West of England and randomised to receive 16 sessions of EMDRp + Treatment as Usual (TAU) or TAU alone. Participants will be assessed at baseline, 6 months and 12 months post-randomisation using several measures of psychotic symptoms, trauma symptoms, anxiety, depression, functioning, service-user defined recovery, health economics indicators and quality of life. Two nested qualitative studies to assess participant feedback of therapy and views of professional stakeholders on the implementation of EMDRp into services will also be conducted. The feasibility of a future definitive efficacy and cost effectiveness evaluation of EMDRp will be tested against several outcomes, including ability to recruit and randomise participants, trial retention at 6- and 12-month follow-up assessments, treatment engagement and treatment fidelity. Conclusions: If it is feasible to deliver a multi-site trial of this intervention, it will be possible to evaluate whether EMDRp represents a beneficial treatment to augment existing evidence-based care of individuals with early psychosis supported by early intervention services.
KW - EMDR
KW - feasibility
KW - psychosis
KW - RCT
KW - trauma
U2 - 10.1111/eip.13071
DO - 10.1111/eip.13071
M3 - Journal article
VL - 15
SP - 1224
EP - 1233
JO - Early Intervention in Psychiatry
JF - Early Intervention in Psychiatry
SN - 1751-7885
IS - 5
ER -