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Fabrication of biocompatible nano-carbonated hydroxyapatite/polymer spongy scaffolds

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Fabrication of biocompatible nano-carbonated hydroxyapatite/polymer spongy scaffolds. / Siddiqi, S. A.; Azhar, U.; Manzoor, F. et al.
In: DIGEST JOURNAL OF NANOMATERIALS AND BIOSTRUCTURES, Vol. 13, No. 2, 01.05.2018, p. 439-450.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Siddiqi, SA, Azhar, U, Manzoor, F, Jamal, A, Tariq, M, Saleem, M, Chaudhry, AA & Rehman, IU 2018, 'Fabrication of biocompatible nano-carbonated hydroxyapatite/polymer spongy scaffolds', DIGEST JOURNAL OF NANOMATERIALS AND BIOSTRUCTURES, vol. 13, no. 2, pp. 439-450.

APA

Siddiqi, S. A., Azhar, U., Manzoor, F., Jamal, A., Tariq, M., Saleem, M., Chaudhry, A. A., & Rehman, I. U. (2018). Fabrication of biocompatible nano-carbonated hydroxyapatite/polymer spongy scaffolds. DIGEST JOURNAL OF NANOMATERIALS AND BIOSTRUCTURES, 13(2), 439-450.

Vancouver

Siddiqi SA, Azhar U, Manzoor F, Jamal A, Tariq M, Saleem M et al. Fabrication of biocompatible nano-carbonated hydroxyapatite/polymer spongy scaffolds. DIGEST JOURNAL OF NANOMATERIALS AND BIOSTRUCTURES. 2018 May 1;13(2):439-450.

Author

Siddiqi, S. A. ; Azhar, U. ; Manzoor, F. et al. / Fabrication of biocompatible nano-carbonated hydroxyapatite/polymer spongy scaffolds. In: DIGEST JOURNAL OF NANOMATERIALS AND BIOSTRUCTURES. 2018 ; Vol. 13, No. 2. pp. 439-450.

Bibtex

@article{287461abffd24785b982848666eb567b,
title = "Fabrication of biocompatible nano-carbonated hydroxyapatite/polymer spongy scaffolds",
abstract = "Spongy scaffolds containing nano-carbonated hydroxyapatite (nCHA), with compositions Ca10(PO4)6-y(CO3)y(OH)2, with y=0,2,4, were prepared by the lyophilization method using different polymers such as natural gelatin (GE), chitosan (CS) and polyvinyl alcohol (PVA), alone or in their combinations. The samples were characterized by using XRD, SEM, and FTIR techniques. All the scaffolds were found to have porosities above 70% and their morphology changed significantly for one nCHA/polymer combination to the other. The nCHA containing scaffolds mediated cytotoxicity (MTT assay) and cell attachment studies were carried out on rat bone marrow derived mesenchymal stem cells (rMSC). Evident cell attachment and no significant cytotoxicity was observed. The preparation of spongy scaffolds and their biocompatibility augment their potential use in tissue engineering and biomedical applications",
keywords = "Nano-carbonated hydroxyapatite, Spongy scaffolds, Mesenchymal stem cells, Hydroxyapatite/polymer scaffolds, MTT Assay, Biocompatibility",
author = "Siddiqi, {S. A.} and U. Azhar and F. Manzoor and A. Jamal and M. Tariq and M. Saleem and Chaudhry, {A. A.} and Rehman, {I. U.}",
year = "2018",
month = may,
day = "1",
language = "English",
volume = "13",
pages = "439--450",
journal = "DIGEST JOURNAL OF NANOMATERIALS AND BIOSTRUCTURES",
issn = "1842-3582",
publisher = "National Institute R and D of Materials Physics",
number = "2",

}

RIS

TY - JOUR

T1 - Fabrication of biocompatible nano-carbonated hydroxyapatite/polymer spongy scaffolds

AU - Siddiqi, S. A.

AU - Azhar, U.

AU - Manzoor, F.

AU - Jamal, A.

AU - Tariq, M.

AU - Saleem, M.

AU - Chaudhry, A. A.

AU - Rehman, I. U.

PY - 2018/5/1

Y1 - 2018/5/1

N2 - Spongy scaffolds containing nano-carbonated hydroxyapatite (nCHA), with compositions Ca10(PO4)6-y(CO3)y(OH)2, with y=0,2,4, were prepared by the lyophilization method using different polymers such as natural gelatin (GE), chitosan (CS) and polyvinyl alcohol (PVA), alone or in their combinations. The samples were characterized by using XRD, SEM, and FTIR techniques. All the scaffolds were found to have porosities above 70% and their morphology changed significantly for one nCHA/polymer combination to the other. The nCHA containing scaffolds mediated cytotoxicity (MTT assay) and cell attachment studies were carried out on rat bone marrow derived mesenchymal stem cells (rMSC). Evident cell attachment and no significant cytotoxicity was observed. The preparation of spongy scaffolds and their biocompatibility augment their potential use in tissue engineering and biomedical applications

AB - Spongy scaffolds containing nano-carbonated hydroxyapatite (nCHA), with compositions Ca10(PO4)6-y(CO3)y(OH)2, with y=0,2,4, were prepared by the lyophilization method using different polymers such as natural gelatin (GE), chitosan (CS) and polyvinyl alcohol (PVA), alone or in their combinations. The samples were characterized by using XRD, SEM, and FTIR techniques. All the scaffolds were found to have porosities above 70% and their morphology changed significantly for one nCHA/polymer combination to the other. The nCHA containing scaffolds mediated cytotoxicity (MTT assay) and cell attachment studies were carried out on rat bone marrow derived mesenchymal stem cells (rMSC). Evident cell attachment and no significant cytotoxicity was observed. The preparation of spongy scaffolds and their biocompatibility augment their potential use in tissue engineering and biomedical applications

KW - Nano-carbonated hydroxyapatite

KW - Spongy scaffolds

KW - Mesenchymal stem cells

KW - Hydroxyapatite/polymer scaffolds

KW - MTT Assay

KW - Biocompatibility

M3 - Journal article

VL - 13

SP - 439

EP - 450

JO - DIGEST JOURNAL OF NANOMATERIALS AND BIOSTRUCTURES

JF - DIGEST JOURNAL OF NANOMATERIALS AND BIOSTRUCTURES

SN - 1842-3582

IS - 2

ER -