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  • Kwakye-Nuako et al 2015

    Rights statement: This is the author’s version of a work that was accepted for publication in International Journal for Parasitology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in International Joural for Parasitology, 45, 11, 2015 DOI: 10.1016/j.ijpara.2015.05.001

    Accepted author manuscript, 1.54 MB, PDF document

    Available under license: CC BY-NC-ND: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License

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First isolation of a new species of Leishmania responsible for human cutaneous leishmaniasis in Ghana and classification in the Leishmania enriettii complex

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Published
  • Godwin Kwakye-Nuako
  • Mba-Tihssommah Mosore
  • Christopher Duplessis
  • Michelle Bates
  • Naiki Puplampu
  • Israel Mensah-Attipoe
  • Kwame Desewu
  • Godwin Afegbe
  • Richard Asmah
  • Manal Jamjoom
  • Patrick Ayeh-Kumi
  • Daniel Boakye
  • Paul Bates
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<mark>Journal publication date</mark>09/2015
<mark>Journal</mark>International Journal for Parasitology
Issue number11
Volume45
Number of pages6
Pages (from-to)679-684
Publication StatusPublished
Early online date19/06/15
<mark>Original language</mark>English

Abstract

An active case detection approach with PCR diagnosis was used in the Ho District of the Volta Region, Ghana that identified individuals with active cutaneous leishmaniasis. Three isolates were successfully cultured and DNA sequences from these were analysed (ribosomal RNA internal transcribed spacer 1; ribosomal protein L23a intergenic spacer; RNA polymerase II large subunit), showing them to be Leishmania, identical to each other but different from all other known Leishmania spp. Phylogenetic analysis showed the parasites to be new members of the Leishmania enriettii complex, which is emerging as a possible new subgenus of Leishmania parasites containing human pathogens.

Bibliographic note

This is the author’s version of a work that was accepted for publication in International Journal for Parasitology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in International Joural for Parasitology, 45, 11, 2015 DOI: 10.1016/j.ijpara.2015.05.001