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Flagellum function and assembly during the Leishmania life cycle.

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Flagellum function and assembly during the Leishmania life cycle. / Gluenz, Eva; Ginger, Michael L.; McKean, Paul G.

In: Current Opinion in Microbiology, Vol. 13, No. 4, 08.2010, p. 473-479.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Gluenz, E, Ginger, ML & McKean, PG 2010, 'Flagellum function and assembly during the Leishmania life cycle.', Current Opinion in Microbiology, vol. 13, no. 4, pp. 473-479. https://doi.org/10.1016/j.mib.2010.05.008

APA

Gluenz, E., Ginger, M. L., & McKean, P. G. (2010). Flagellum function and assembly during the Leishmania life cycle. Current Opinion in Microbiology, 13(4), 473-479. https://doi.org/10.1016/j.mib.2010.05.008

Vancouver

Gluenz E, Ginger ML, McKean PG. Flagellum function and assembly during the Leishmania life cycle. Current Opinion in Microbiology. 2010 Aug;13(4):473-479. https://doi.org/10.1016/j.mib.2010.05.008

Author

Gluenz, Eva ; Ginger, Michael L. ; McKean, Paul G. / Flagellum function and assembly during the Leishmania life cycle. In: Current Opinion in Microbiology. 2010 ; Vol. 13, No. 4. pp. 473-479.

Bibtex

@article{01916991e7d24e369d6cc9e3a3eff492,
title = "Flagellum function and assembly during the Leishmania life cycle.",
abstract = "During a complex digenetic life cycle flagellated Leishmania parasites alternate between promastigote and amastigote forms which differ significantly in cellular morphology and flagellum length. Recent studies have provided important new insights into mechanisms by which Leishmania regulate expression of genes required for flagellum assembly, and mechanisms used to modify flagellum length. While the critical role of the promastigote flagellum in parasite biology has long been appreciated, the importance of the amastigote flagellum has often been disregarded. However, recent work suggests that the 'rudimentary' amastigote flagellum may serve indispensable roles in cellular organisation, and/or sensory perception, which are critical for intracellular survival of Leishmania within host macrophages.",
author = "Eva Gluenz and Ginger, {Michael L.} and McKean, {Paul G.}",
year = "2010",
month = aug,
doi = "10.1016/j.mib.2010.05.008",
language = "English",
volume = "13",
pages = "473--479",
journal = "Current Opinion in Microbiology",
issn = "1369-5274",
publisher = "Elsevier Limited",
number = "4",

}

RIS

TY - JOUR

T1 - Flagellum function and assembly during the Leishmania life cycle.

AU - Gluenz, Eva

AU - Ginger, Michael L.

AU - McKean, Paul G.

PY - 2010/8

Y1 - 2010/8

N2 - During a complex digenetic life cycle flagellated Leishmania parasites alternate between promastigote and amastigote forms which differ significantly in cellular morphology and flagellum length. Recent studies have provided important new insights into mechanisms by which Leishmania regulate expression of genes required for flagellum assembly, and mechanisms used to modify flagellum length. While the critical role of the promastigote flagellum in parasite biology has long been appreciated, the importance of the amastigote flagellum has often been disregarded. However, recent work suggests that the 'rudimentary' amastigote flagellum may serve indispensable roles in cellular organisation, and/or sensory perception, which are critical for intracellular survival of Leishmania within host macrophages.

AB - During a complex digenetic life cycle flagellated Leishmania parasites alternate between promastigote and amastigote forms which differ significantly in cellular morphology and flagellum length. Recent studies have provided important new insights into mechanisms by which Leishmania regulate expression of genes required for flagellum assembly, and mechanisms used to modify flagellum length. While the critical role of the promastigote flagellum in parasite biology has long been appreciated, the importance of the amastigote flagellum has often been disregarded. However, recent work suggests that the 'rudimentary' amastigote flagellum may serve indispensable roles in cellular organisation, and/or sensory perception, which are critical for intracellular survival of Leishmania within host macrophages.

U2 - 10.1016/j.mib.2010.05.008

DO - 10.1016/j.mib.2010.05.008

M3 - Journal article

VL - 13

SP - 473

EP - 479

JO - Current Opinion in Microbiology

JF - Current Opinion in Microbiology

SN - 1369-5274

IS - 4

ER -