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Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance

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Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance. / Porter, D. W.; Kerr, B. D.; Flatt, P. R. et al.
In: Diabetes, Obesity and Metabolism, Vol. 12, No. 10, 10.2010, p. 891-899.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

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Porter DW, Kerr BD, Flatt PR, Hölscher C, Gault VA. Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance. Diabetes, Obesity and Metabolism. 2010 Oct;12(10):891-899. doi: 10.1111/j.1463-1326.2010.01259.x

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Porter, D. W. ; Kerr, B. D. ; Flatt, P. R. et al. / Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance. In: Diabetes, Obesity and Metabolism. 2010 ; Vol. 12, No. 10. pp. 891-899.

Bibtex

@article{c1ec0b24b7a04703950087eb4e5592fa,
title = "Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance",
abstract = "Liraglutide is a long-acting glucagon-like peptide-1 (GLP-1) mimetic which is a treatment option for type 2 diabetes. GLP-1 peptides, including Liraglutide, cross the blood-brain barrier and may additionally act to improve brain function. The present study tested the hypothesis that, in addition to its antihyperglycaemic actions, peripheral administration of Liraglutide exerts positive actions on cognitive function in mice with high fat dietary-induced obesity and insulin resistance.",
keywords = "Animals, Blood Glucose, Cognition, Diabetes Mellitus, Type 2, Glucagon-Like Peptide 1, Hypoglycemic Agents, Insulin Resistance, Male, Memory, Mice, Obesity",
author = "Porter, {D. W.} and Kerr, {B. D.} and Flatt, {P. R.} and Christian H{\"o}lscher and Gault, {V. A.}",
note = "{\textcopyright} 2010 Blackwell Publishing Ltd.",
year = "2010",
month = oct,
doi = "10.1111/j.1463-1326.2010.01259.x",
language = "English",
volume = "12",
pages = "891--899",
journal = "Diabetes, Obesity and Metabolism",
issn = "1463-1326",
publisher = "Wiley-Blackwell",
number = "10",

}

RIS

TY - JOUR

T1 - Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance

AU - Porter, D. W.

AU - Kerr, B. D.

AU - Flatt, P. R.

AU - Hölscher, Christian

AU - Gault, V. A.

N1 - © 2010 Blackwell Publishing Ltd.

PY - 2010/10

Y1 - 2010/10

N2 - Liraglutide is a long-acting glucagon-like peptide-1 (GLP-1) mimetic which is a treatment option for type 2 diabetes. GLP-1 peptides, including Liraglutide, cross the blood-brain barrier and may additionally act to improve brain function. The present study tested the hypothesis that, in addition to its antihyperglycaemic actions, peripheral administration of Liraglutide exerts positive actions on cognitive function in mice with high fat dietary-induced obesity and insulin resistance.

AB - Liraglutide is a long-acting glucagon-like peptide-1 (GLP-1) mimetic which is a treatment option for type 2 diabetes. GLP-1 peptides, including Liraglutide, cross the blood-brain barrier and may additionally act to improve brain function. The present study tested the hypothesis that, in addition to its antihyperglycaemic actions, peripheral administration of Liraglutide exerts positive actions on cognitive function in mice with high fat dietary-induced obesity and insulin resistance.

KW - Animals

KW - Blood Glucose

KW - Cognition

KW - Diabetes Mellitus, Type 2

KW - Glucagon-Like Peptide 1

KW - Hypoglycemic Agents

KW - Insulin Resistance

KW - Male

KW - Memory

KW - Mice

KW - Obesity

U2 - 10.1111/j.1463-1326.2010.01259.x

DO - 10.1111/j.1463-1326.2010.01259.x

M3 - Journal article

C2 - 20920042

VL - 12

SP - 891

EP - 899

JO - Diabetes, Obesity and Metabolism

JF - Diabetes, Obesity and Metabolism

SN - 1463-1326

IS - 10

ER -