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Research output: Contribution to Journal/Magazine › Literature review › peer-review
Research output: Contribution to Journal/Magazine › Literature review › peer-review
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TY - JOUR
T1 - Gene delivery with organic electronic biomaterials
AU - Clancy, Kathryn
AU - Hardy, John George
N1 - © 2017 Bentham Science Publishers
PY - 2017/9
Y1 - 2017/9
N2 - Gene therapy may be capable of treating a variety of diseases, a prerequisite of which is the successful delivery of polynucleic acids (e.g., DNA, RNA) to a patient’s cells. Delivery can be achieved technologically (e.g., using electroporation), using viruses (natural gene delivery vectors) or non-viral vectors (e.g., lipids, nanoparticles, polymers). This article aims to give the reader an overview of the use of organic electronic materials (i.e., fullerenes, graphenes and conjugated polymers) as non-viral gene delivery vectors.
AB - Gene therapy may be capable of treating a variety of diseases, a prerequisite of which is the successful delivery of polynucleic acids (e.g., DNA, RNA) to a patient’s cells. Delivery can be achieved technologically (e.g., using electroporation), using viruses (natural gene delivery vectors) or non-viral vectors (e.g., lipids, nanoparticles, polymers). This article aims to give the reader an overview of the use of organic electronic materials (i.e., fullerenes, graphenes and conjugated polymers) as non-viral gene delivery vectors.
KW - Organic electronics
KW - carbon nanotubes
KW - fullerene
KW - graphene
KW - conjugated polymer
KW - gene delivery
KW - gene therapy
KW - biodegradable
U2 - 10.2174/1381612823666170710124137
DO - 10.2174/1381612823666170710124137
M3 - Literature review
VL - 23
SP - 3614
EP - 3625
JO - Current Pharmaceutical Design
JF - Current Pharmaceutical Design
SN - 1873-4286
IS - 24
ER -