Rights statement: The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-642-13214-8_29
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Final published version
Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review
Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review
}
TY - GEN
T1 - Genome visualization in space
AU - Soriano Marcolino, Leandro
AU - Couto, Bráulio R. G. M.
AU - dos Santos, Marcos A.
N1 - The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-642-13214-8_29
PY - 2010
Y1 - 2010
N2 - Phylogeny is an important field to understand evolution and the organization of life. However, most methods depend highly on manual study and analysis, making the construction of phylogeny error prone. Linear Algebra methods are known to be efficient to deal with the semantic relationships between a large number of elements in spaces of high dimensionality. Therefore, they can be useful to help the construction of phylogenetic trees. The ability to visualize the relationships between genomes is crucial in this process. In this paper, a linear algebra method, followed by optimization, is used to generate a visualization of a set of complete genomes. Using the proposed method we were able to visualize the relationships of 64 complete mitochondrial genomes, organized as six different groups, and of 31 complete mitochondrial genomes of mammals, organized as nine different groups. The prespecified groups could be seen clustered together in the visualization, and similar species were represented close together. Besides, there seems to be an evolutionary influence in the organization of the graph.
AB - Phylogeny is an important field to understand evolution and the organization of life. However, most methods depend highly on manual study and analysis, making the construction of phylogeny error prone. Linear Algebra methods are known to be efficient to deal with the semantic relationships between a large number of elements in spaces of high dimensionality. Therefore, they can be useful to help the construction of phylogenetic trees. The ability to visualize the relationships between genomes is crucial in this process. In this paper, a linear algebra method, followed by optimization, is used to generate a visualization of a set of complete genomes. Using the proposed method we were able to visualize the relationships of 64 complete mitochondrial genomes, organized as six different groups, and of 31 complete mitochondrial genomes of mammals, organized as nine different groups. The prespecified groups could be seen clustered together in the visualization, and similar species were represented close together. Besides, there seems to be an evolutionary influence in the organization of the graph.
U2 - 10.1007/978-3-642-13214-8_29
DO - 10.1007/978-3-642-13214-8_29
M3 - Conference contribution/Paper
SN - 9783642132131
T3 - Advances in Intelligent and Soft Computing
SP - 225
EP - 232
BT - Advances in Bioinformatics
A2 - Rocha, Miguel P.
A2 - Riverola , Florentino Fernández
A2 - Shatkay, Hagit
A2 - Corchado, Juan Manuel
PB - Springer
ER -