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  • Za_rate_Potes_and_Dierking_2021

    Rights statement: This is the author’s version of a work that was accepted for publication in Immunity. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Immunity, 54, 7, 2021 DOI: 10.1016/j.immuni.2021.06.004

    Accepted author manuscript, 324 KB, PDF document

    Embargo ends: 13/07/22

    Available under license: CC BY-NC-ND

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Guard proteins keep watch at epithelial walls

Research output: Contribution to Journal/MagazineJournal article

Published
<mark>Journal publication date</mark>13/07/2021
<mark>Journal</mark>Immunity
Issue number7
Volume54
Number of pages3
Pages (from-to)1366-1368
Publication StatusPublished
<mark>Original language</mark>English

Abstract

Cells can detect pathogens through guard proteins that sense disturbances in core cellular processes, but the exact mechanisms often remain elusive. In this issue of Immunity, Orzalli et al. identify Bcl-2 family members as guard proteins that detect virus-induced translational inhibition and induce pyroptosis in human keratinocytes.

Bibliographic note

This is the author’s version of a work that was accepted for publication in Immunity. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Immunity, 54, 7, 2021 DOI: 10.1016/j.immuni.2021.06.004