To predict the class label from a partially observable activity sequence can be quite challenging due to the high degree of similarity existing in early segments of different activities. In this paper, an innovative HARDness-Guided Discrimination Network (HARDer-Net) is proposed to evaluate the relationship between similar activity pairs that are extremely hard to discriminate. To train our HARDer-Net, an innovative adversarial learning scheme has been designed, providing our network with the strength to extract subtle discrimination information for the prediction of 3D early activities. Moreover, to enhance the adversarial learning scheme efficacy of our model for 3D early action prediction, we construct a Hardness-Guided bank that dynamically records the hard similar samples and conducts reward-guided selections of these recorded hard samples using a deep reinforcement learning scheme. The proposed method significantly enhances the capability of the model to discern fine-grained differences in early activity sequences. Several widely-used activity datasets are used to evaluate our proposed HARDer-Net, and we achieve state-of-the-art performance across all the evaluated datasets.